GPKOW and WDR83

Number of citations of the paper that reports this interaction (PubMedID 22365833)
0

Data Source:
BioGRID (two hybrid, two hybrid)

		GPKOW	WDR83
Description		G-patch domain and KOW motifs	WD repeat domain 83
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex	Nucleus Spliceosomal Complex Cytoplasm Lysosome Endosome Membrane Catalytic Step 2 Spliceosome
	Molecular Function	Nucleic Acid Binding RNA Binding Protein Binding	Protein Binding
	Biological Process	MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing	RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome Response To Hypoxia Neural Tube Closure MRNA Processing RNA Splicing Response To Wounding Response To Lipopolysaccharide Regulation Of Canonical NF-kappaB Signal Transduction Placenta Blood Vessel Development Inflammatory Response To Wounding
Pathways		mRNA Splicing - Major Pathway	MAP2K and MAPK activation
Drugs
Diseases
GWAS
Interacting Genes		47 interacting genes: APP ARMCX1 BUD13 CCDC57 CNKSR3 DDIT4L EFHC2 FBXO7 GMPPA GOLGA2 GSTM5 HOOK2 HSF2BP IKBKG KANK2 LNX1 LRP2BP LZTS1 MAD1L1 MEOX2 MESD MID2 MTUS2 NINL OGT PHF1 PIBF1 PICK1 POLR2G PPP1CA PRKAR1B PRPF4 PRPF8 REL ROPN1 SH3GL1 SORBS3 SPDYE4 TCEA1 TCEA2 TRAF2 TRIM23 TRIM27 VPS52 WDR77 WDR83 ZMYND12	36 interacting genes: BAG2 BCAS2 BCL6 CRB3 CRK CRYAA EGLN3 EXOSC1 FAM124B FRS3 GNE GPKOW GTSE1 HNRNPH2 HOXA1 HSPB1 KCTD9 KDM1A KEAP1 LONRF1 LSM3 NOXA1 PARD6A PARD6B PCBP2 PRKAB2 RACK1 SAP30BP SF1 SRSF8 TLX3 TOE1 VAC14 WBP4 ZC3H7A ZNF76
Entrez ID		27238	84292
HPRD ID		06737	14730
Ensembl ID		ENSG00000068394	ENSG00000123154
Uniprot IDs		Q92917	Q9BRX9
PDB IDs		7DVQ 7QTT 8CH6
Enriched GO Terms of Interacting Partners?		Cytoplasm Protein Binding Identical Protein Binding Regulation Of Autophagy Positive Regulation Of Autophagy	Nucleoplasm Nucleus Identical Protein Binding RNA Binding Nucleic Acid Binding Spliceosomal Complex MRNA Splicing, Via Spliceosome RNA Processing PAR Polarity Complex RNA Splicing, Via Transesterification Reactions RNA Splicing Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Protein Binding Establishment Or Maintenance Of Apical/basal Cell Polarity MRNA Metabolic Process MRNA Processing Establishment Or Maintenance Of Cell Polarity RNA Metabolic Process MRNA Cis Splicing, Via Spliceosome Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Precatalytic Spliceosome
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