GPKOW and PRPF4

Number of citations of the paper that reports this interaction (PubMedID 22365833)
0

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		GPKOW	PRPF4
Description		G-patch domain and KOW motifs	pre-mRNA splicing tri-snRNP complex factor PRPF4
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex	Nucleus Nucleoplasm Spliceosomal Complex Cajal Body Nuclear Speck U4/U6 X U5 Tri-snRNP Complex U4/U6 SnRNP U2-type Precatalytic Spliceosome Spliceosomal SnRNP Complex
	Molecular Function	Nucleic Acid Binding RNA Binding Protein Binding	Protein Binding U6 SnRNA Binding U4 SnRNA Binding
	Biological Process	MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing	RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome RNA Processing MRNA Processing RNA Splicing
Pathways		mRNA Splicing - Major Pathway	mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS			White matter growth ( 29682794)
Interacting Genes		47 interacting genes: APP ARMCX1 BUD13 CCDC57 CNKSR3 DDIT4L EFHC2 FBXO7 GMPPA GOLGA2 GSTM5 HOOK2 HSF2BP IKBKG KANK2 LNX1 LRP2BP LZTS1 MAD1L1 MEOX2 MESD MID2 MTUS2 NINL OGT PHF1 PIBF1 PICK1 POLR2G PPP1CA PRKAR1B PRPF4 PRPF8 REL ROPN1 SH3GL1 SORBS3 SPDYE4 TCEA1 TCEA2 TRAF2 TRIM23 TRIM27 VPS52 WDR77 WDR83 ZMYND12	10 interacting genes: APP ATP5MF CEBPA CLK1 GPKOW PPIH SRSF1 TGFBR1 U2AF1 WBP4
Entrez ID		27238	9128
HPRD ID		06737	08479
Ensembl ID		ENSG00000068394	ENSG00000136875
Uniprot IDs		Q92917	O43172 Q5T1M7
PDB IDs		7DVQ 7QTT 8CH6	1MZW 3JCR 5O9Z 6AH0 6AHD 6QW6 6QX9 8H6E 8H6J 8H6K 8H6L 8Q7N 8QO9 8QOZ 8QPA 8QPB 8QPE 8QXD 8QZS 8R08 8R09 8R0A 8R0B 8RM5 8Y6O
Enriched GO Terms of Interacting Partners?		Cytoplasm Protein Binding Identical Protein Binding Regulation Of Autophagy Positive Regulation Of Autophagy	Spliceosomal Complex RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome RNA Splicing MRNA Processing RS Domain Binding MRNA Metabolic Process RNA Metabolic Process RNA Processing Nuclear Speck Nucleobase-containing Compound Metabolic Process Nucleic Acid Binding Nucleic Acid Metabolic Process Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Gland Development Animal Organ Regeneration RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Acetylcholine Receptor Activator Activity Macromolecule Metabolic Process Lipoprotein Particle Positive Regulation Of Protein Import Nucleus Regulation Of Stem Cell Proliferation Response To Vitamin B2 C/EBP Complex Protein Localization To P-body Catalytic Step 2 Spliceosome Vascular Endothelial Cell Proliferation Epicardium Morphogenesis PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization CHOP-C/EBP Complex Liver Development Proepicardium Development Angiogenesis Involved In Coronary Vascular Morphogenesis Transforming Growth Factor Beta Ligand-receptor Complex U4/U6 SnRNP Notch Signaling Pathway Response To Norepinephrine
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