FERMT3 and LSM8

Number of citations of the paper that reports this interaction (PMID 15231747)
44

Data Source:
HPRD (two hybrid)

		FERMT3	LSM8
Gene Name		fermitin family member 3	LSM8 homolog, U6 small nuclear RNA associated (S. cerevisiae)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Podosome Membrane Cell Junction Cell Projection Extracellular Vesicular Exosome	Spliceosomal Complex U4/U6 X U5 Tri-snRNP Complex
	Molecular Function	Integrin Binding	Protein Binding U6 SnRNA Binding U6 SnRNA 3'-end Binding Poly(A) RNA Binding
	Biological Process	Leukocyte Cell-cell Adhesion Integrin-mediated Signaling Pathway Integrin Activation Regulation Of Cell-cell Adhesion Mediated By Integrin Substrate Adhesion-dependent Cell Spreading Platelet Aggregation	MRNA Splicing, Via Spliceosome
Pathways
Drugs
Diseases
GWAS		Attention deficit hyperactivity disorder ( 21784300)
Protein-Protein Interactions		4 interactors: APP EXOSC10 LSM8 TINF2	49 interactors: ARNT BCKDK COL23A1 DBF4 DCP1A DCP1B DPAGT1 ECHDC2 EFTUD2 EXOSC10 EXOSC6 FAM63A FERMT3 GMPPA GTF2I HSPA9 IFNLR1 IGHMBP2 ISOC2 ITSN2 KCTD3 LSM2 LSM3 LSM4 LSM5 LSM6 LSM7 MGA MPRIP MRPL48 MTHFR NAGK NME4 PDCD2 PGD PHF11 RBM5 RPL24 RSC1A1 RSL24D1 SEPT10 SEPT5 SMU1 SNRNP200 SNRPB SNRPD1 TALDO1 THUMPD3 UPF1
Entrez ID		83706	51691
HPRD ID		07440	06288
Ensembl ID		ENSG00000149781
Uniprot IDs		Q86UX7	A4D0W0 O95777
PDB IDs		2YS3
Enriched GO Terms of Interacting Partners?		MRNA Metabolic Process RNA Processing Negative Regulation Of Protein ADP-ribosylation Nuclear Retention Of Unspliced Pre-mRNA At The Site Of Transcription Regulation Of Protein ADP-ribosylation Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Negative Regulation Of Protein Glycosylation Nuclear Polyadenylation-dependent RRNA Catabolic Process CUT Catabolic Process Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Protein Localization To Chromosome, Telomeric Region Negative Regulation Of Telomere Maintenance Via Telomerase Axon Choice Point Recognition Nuclear MRNA Surveillance Telomere Assembly RNA Surveillance Nucleobase-containing Compound Metabolic Process Neuron Remodeling Histone MRNA Catabolic Process Negative Regulation Of Telomere Maintenance Dosage Compensation By Inactivation Of X Chromosome Regulation Of Protein Glycosylation Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Intracellular MRNA Localization Positive Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase MRNA Processing Dosage Compensation RRNA Catabolic Process Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Glycoprotein Metabolic Process Maturation Of 5.8S RRNA Nitrogen Compound Metabolic Process Regulation Of Telomere Maintenance Cellular Copper Ion Homeostasis Histone MRNA Metabolic Process Copper Ion Homeostasis Suckling Behavior Cellular Localization Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Glycoprotein Biosynthetic Process Protein Localization To Chromosome Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity RNA Phosphodiester Bond Hydrolysis, Exonucleolytic	Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic Nuclear-transcribed MRNA Catabolic Process MRNA Metabolic Process MRNA Catabolic Process Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay RNA Catabolic Process Nucleobase-containing Compound Metabolic Process Aromatic Compound Catabolic Process RNA Splicing Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process MRNA Processing RNA Processing Catabolic Process Gene Expression RNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Cellular Macromolecule Catabolic Process Ribonucleoprotein Complex Biogenesis Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Cellular Metabolic Process Histone MRNA Metabolic Process Pentose Biosynthetic Process Metabolic Process Histone MRNA Catabolic Process Dosage Compensation By Inactivation Of X Chromosome Spliceosomal Complex Assembly Dosage Compensation Ribonucleoprotein Complex Assembly Ribosome Biogenesis Pentose-phosphate Shunt Glyceraldehyde-3-phosphate Metabolic Process Nucleobase-containing Small Molecule Metabolic Process Glucose 6-phosphate Metabolic Process RRNA Processing NcRNA Metabolic Process Starch Catabolic Process Nuclear Retention Of Unspliced Pre-mRNA At The Site Of Transcription Response To Type III Interferon Dolichol Biosynthetic Process NADP Metabolic Process RRNA Metabolic Process Spliceosomal SnRNP Assembly Carbohydrate Biosynthetic Process D-gluconate Metabolic Process Response To Vitamin B2
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