FERMT3 and EXOSC10

Number of citations of the paper that reports this interaction (PMID 15231747)
44

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		FERMT3	EXOSC10
Gene Name		fermitin family member 3	exosome component 10
Image
Gene Ontology Annotations	Cellular Component	Podosome Membrane Cell Junction Cell Projection Extracellular Vesicular Exosome	Nuclear Exosome (RNase Complex) Exosome (RNase Complex) Nucleus Nucleoplasm Nucleolus Cytoplasm Membrane Transcriptionally Active Chromatin
	Molecular Function	Integrin Binding	Nucleotide Binding Exoribonuclease Activity Protein Binding 3'-5' Exonuclease Activity Poly(A) RNA Binding
	Biological Process	Leukocyte Cell-cell Adhesion Integrin-mediated Signaling Pathway Integrin Activation Regulation Of Cell-cell Adhesion Mediated By Integrin Substrate Adhesion-dependent Cell Spreading Platelet Aggregation	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Maturation Of 5.8S RRNA Nuclear-transcribed MRNA Catabolic Process Dosage Compensation By Inactivation Of X Chromosome Nuclear MRNA Surveillance CUT Catabolic Process Nuclear Polyadenylation-dependent RRNA Catabolic Process Histone MRNA Catabolic Process Nuclear Retention Of Unspliced Pre-mRNA At The Site Of Transcription RNA Phosphodiester Bond Hydrolysis, Exonucleolytic
Pathways
Drugs
Diseases
GWAS		Attention deficit hyperactivity disorder ( 21784300)
Protein-Protein Interactions		4 interactors: APP EXOSC10 LSM8 TINF2	35 interactors: ALDH1B1 B9D1 CHPF CIB1 DIS3 DXO EIF3M EXOSC4 EXOSC5 EXOSC6 EXOSC7 EXOSC8 FERMT3 FOXRED1 IMMT LCAT LSM2 LSM8 MPHOSPH6 MPP6 NOMO1 NOMO2 PTGES2 RPE RUVBL2 SCRIB SKIV2L SSRP1 TARDBP TOX4 UPF2 USP16 USP21 XRN1 XRN2
Entrez ID		83706	5394
HPRD ID		07440	16180
Ensembl ID		ENSG00000149781	ENSG00000171824
Uniprot IDs		Q86UX7	Q01780 Q96G78
PDB IDs		2YS3	2CPR 3SAF 3SAG 3SAH
Enriched GO Terms of Interacting Partners?		MRNA Metabolic Process RNA Processing Negative Regulation Of Protein ADP-ribosylation Nuclear Retention Of Unspliced Pre-mRNA At The Site Of Transcription Regulation Of Protein ADP-ribosylation Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Negative Regulation Of Protein Glycosylation Nuclear Polyadenylation-dependent RRNA Catabolic Process CUT Catabolic Process Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Protein Localization To Chromosome, Telomeric Region Negative Regulation Of Telomere Maintenance Via Telomerase Axon Choice Point Recognition Nuclear MRNA Surveillance Telomere Assembly RNA Surveillance Nucleobase-containing Compound Metabolic Process Neuron Remodeling Histone MRNA Catabolic Process Negative Regulation Of Telomere Maintenance Dosage Compensation By Inactivation Of X Chromosome Regulation Of Protein Glycosylation Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Intracellular MRNA Localization Positive Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase MRNA Processing Dosage Compensation RRNA Catabolic Process Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Glycoprotein Metabolic Process Maturation Of 5.8S RRNA Nitrogen Compound Metabolic Process Regulation Of Telomere Maintenance Cellular Copper Ion Homeostasis Histone MRNA Metabolic Process Copper Ion Homeostasis Suckling Behavior Cellular Localization Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Glycoprotein Biosynthetic Process Protein Localization To Chromosome Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity RNA Phosphodiester Bond Hydrolysis, Exonucleolytic	Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic RNA Catabolic Process Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Nuclear-transcribed MRNA Catabolic Process MRNA Catabolic Process MRNA Metabolic Process RRNA Metabolic Process RRNA Processing Aromatic Compound Catabolic Process Cellular Macromolecule Catabolic Process Ribosome Biogenesis Ribonucleoprotein Complex Biogenesis RNA Phosphodiester Bond Hydrolysis, Exonucleolytic Catabolic Process RNA Metabolic Process NcRNA Metabolic Process Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Nuclear MRNA Surveillance Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process DNA Deamination RNA Surveillance Nucleic Acid Phosphodiester Bond Hydrolysis RNA Phosphodiester Bond Hydrolysis Gene Expression Maturation Of 5.8S RRNA Histone MRNA Catabolic Process RRNA Catabolic Process Cellular Metabolic Process DNA Modification Protein K63-linked Deubiquitination Histone Deubiquitination Histone MRNA Metabolic Process DNA Metabolic Process Chromatin Modification Regulation Of Cell Adhesion Mediated By Integrin Positive Regulation Of Male Germ Cell Proliferation Metabolic Process Chromatin Remodeling MRNA Processing Regulation Of RNA Stability Chromatin Organization Thrombopoietin-mediated Signaling Pathway Posttranscriptional Regulation Of Gene Expression Histone H2A K63-linked Deubiquitination Regulation Of Male Germ Cell Proliferation Endomitotic Cell Cycle
Tagcloud ?			18s adopt assumed candidates carry defects exosome extensively functionally fundamental hela homolog its2 itss nucleolar polycistronic posing precede precursors processing recruit ribosomopathies rnas rrna rrnas rrp6 spacers transcribed yeast
Tagcloud (Difference) ?			18s adopt assumed candidates carry defects exosome extensively functionally fundamental hela homolog its2 itss nucleolar polycistronic posing precede precursors processing recruit ribosomopathies rnas rrna rrnas rrp6 spacers transcribed yeast
Tagcloud (Intersection) ?