PTPN22 and ZAP70

  • Number of citations of the paper that reports this interaction (PMID 16461343)
  • 57
  • Data Source:
  • HPRD (in vivo)

PTPN22

ZAP70

Gene Name protein tyrosine phosphatase, non-receptor type 22 (lymphoid) zeta-chain (TCR) associated protein kinase 70kDa
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 9 interactors: CBL CD247 CD3E CSK GRB2 LCK PRKCD VAV1 ZAP70 58 interactors: ABL1 ACP1 ANAPC11 APP ASB3 CARD11 CBL CBLB CBLC CD247 CD3E CD5 CD79B CRK CSK DBNL DEF6 DUSP3 EGFR ERBB3 FCGR3A FCRL3 FYN GAB2 GRB2 IFNAR1 LAT LAX1 LCK LCP2 MUC1 NDUFB8 NFAM1 NR0B2 PAG1 PLCG1 PRLR PTK2B PTPN22 PTPN3 PTPN6 PTPRC RASA1 SH2B3 SH3BP2 SHB SHC1 SIT1 SLA SLA2 SLAMF6 SOS1 TUBA1A TUBA4A TUBB TYROBP VAV1 WIPF1
Entrez ID 26191 7535
HPRD ID 06100 01495
Ensembl ID ENSG00000134242 ENSG00000115085
Uniprot IDs B4DZW8 Q9Y2R2 P43403
PDB IDs 2P6X 2QCJ 2QCT 3BRH 3H2X 3OLR 3OMH 4J51 1FBV 1M61 1U59 2CBL 2OQ1 2OZO 2Y1N 3ZNI 4A4B 4A4C 4K2R
Enriched GO Terms of Interacting Partners?
Tagcloud ?
aitd  antigens  autoimmunity  breakdown  cd28  cd40  ctla4  develops  discrepancy  fcrl3  happen  hashimoto  humoral  hyperthyroidism  hypothyroidism  il2ra  immunogenicity  immunoregulatory  infiltrating  insults  iodine  multifactorial  parity  preponderance  thymus  thyroglobulin  thyroid  thyrotropin  wrong 
cd3  coimmunoprecipitated  compartment  cytosol  detergent  failing  grb2  hsos1  insoluble  jurkat  localize  nonidet  p145  p21ras  p36  p95  participates  particulate  phospholipase  phosphoprotein  plc  redistributed  shc  tcr  vav  vicinity  zeta 
Tagcloud (Difference) ?
aitd  antigens  autoimmunity  breakdown  cd28  cd40  ctla4  develops  discrepancy  fcrl3  happen  hashimoto  humoral  hyperthyroidism  hypothyroidism  il2ra  immunogenicity  immunoregulatory  infiltrating  insults  iodine  multifactorial  parity  preponderance  thymus  thyroglobulin  thyroid  thyrotropin  wrong 
cd3  coimmunoprecipitated  compartment  cytosol  detergent  failing  grb2  hsos1  insoluble  jurkat  localize  nonidet  p145  p21ras  p36  p95  participates  particulate  phospholipase  phosphoprotein  plc  redistributed  shc  tcr  vav  vicinity  zeta 
Tagcloud (Intersection) ?