PRPF31 and PDE4DIP

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		PRPF31	PDE4DIP
Gene Name		pre-mRNA processing factor 31	phosphodiesterase 4D interacting protein
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus U2-type Spliceosomal Complex U4 SnRNP U4atac SnRNP Cajal Body Nuclear Speck U4/U6 X U5 Tri-snRNP Complex MLL1 Complex	Nucleus Cytoplasm Golgi Apparatus Centrosome Myofibril
	Molecular Function	Protein Binding Ribonucleoprotein Complex Binding Poly(A) RNA Binding SnRNP Binding	Protein Binding Enzyme Binding
	Biological Process	Spliceosomal Tri-snRNP Complex Assembly MRNA Splicing, Via Spliceosome	Cellular Protein Complex Assembly
Pathways
Drugs
Diseases
GWAS			Capecitabine sensitivity ( 22864933)
Protein-Protein Interactions		55 interactors: AES C1QTNF1 CALCOCO2 CCDC136 CCDC57 CDCA7L CEP70 FANCA GNB2L1 GOLGA2 HNRNPH2 HNRNPK JAKMIP2 KCTD6 KHDRBS2 KHDRBS3 KRT15 KRT40 KRTAP10-1 KRTAP10-3 KRTAP10-8 KRTAP10-9 LDOC1 LURAP1 MID2 MIPOL1 MKRN3 MTUS2 NHP2L1 NOTCH2NL PDE4DIP PHC2 PHF5A PNMA1 PNMA2 PPIH PRICKLE1 PRPF3 PRPF4 PSTPIP1 RBM25 RBM4 RBMY1A1 RBMY1F SIAH1 SSX2IP STX11 TADA2A TFIP11 TMCC2 TP53BP2 TRIM27 TSGA10 ZNF250 ZNF587	64 interactors: ADH1B AEN ANKRD11 ARNT2 BYSL C14orf105 C19orf66 C1orf109 CCDC146 CDC5L CDKN1A CHCHD3 FAM161A FAM74A4 FCHSD2 FES FHL1 GADD45G GFI1B GOLGA8EP GOLGA8F HAUS1 IMMT ITSN2 KDM1A KLC3 KLC4 KRAS KRT18 KRT31 LAMTOR3 LENG1 LMO4 MAPRE1 MIF4GD MTUS2 NAA10 NEFL NEK2 OSGEP PDE4D PFDN1 PIAS4 PPP1R18 PRNP PRPF31 RTP5 SCNM1 SDCBP SH2D4A SMN1 SNCA TFIP11 TK1 TNIK TRAF4 UTP14C VAC14 ZBTB38 ZFYVE21 ZNF408 ZNF512B ZNF581 ZSCAN26
Entrez ID		26121	9659
HPRD ID		05917	10482
Ensembl ID		ENSG00000105618	ENSG00000178104
Uniprot IDs		E7ESA8 F1T0A4 F1T0A5 Q8WWY3	F8WAP3 Q5VU43
PDB IDs		2OZB 3SIU 3SIV
Enriched GO Terms of Interacting Partners?		RNA Splicing MRNA Processing MRNA Metabolic Process RNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Regulation Of Alternative MRNA Splicing, Via Spliceosome Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Regulation Of MRNA Splicing, Via Spliceosome Spermatogenesis Male Gamete Generation Negative Regulation Of Viral Release From Host Cell Regulation Of Gene Expression Regulation Of MRNA Processing Negative Regulation Of Viral Transcription Regulation Of Viral Release From Host Cell Regulation Of RNA Splicing Gamete Generation Protein Trimerization Spliceosomal Complex Disassembly Negative Regulation Of Cardiac Muscle Cell Myoblast Differentiation Reproduction Sexual Reproduction Regulation Of Viral Process Multicellular Organismal Reproductive Process Regulation Of RNA Metabolic Process Multicellular Organism Reproduction Regulation Of Nitrogen Compound Metabolic Process Regulation Of Lipid Transport By Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Interleukin-2 Secretion Positive Regulation Of Aldosterone Secretion Positive Regulation Of CAMP Catabolic Process Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Negative Regulation Of Protein Binding Positive Regulation Of Cell Death Single Organism Reproductive Process Negative Regulation Of Wnt Signaling Pathway Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Hydrogen Peroxide-induced Neuron Death Cellular Component Assembly	Developmental Process Response To Copper Ion RNA Metabolic Process Anatomical Structure Development Nucleobase-containing Compound Metabolic Process Regulation Of Microtubule Polymerization Multicellular Organismal Development Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Response To Copper Ion Response To Mineralocorticoid Cellular Nitrogen Compound Metabolic Process Positive Regulation Of JNK Cascade Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Regulation Of Apoptotic Process Regulation Of Phosphorus Metabolic Process Regulation Of Microtubule Cytoskeleton Organization Regulation Of Cell Death Regulation Of Phosphorylation Response To Glucocorticoid Regulation Of JNK Cascade Activation Of MAPKK Activity Positive Regulation Of Protein Kinase Activity Nitrogen Compound Metabolic Process Response To Corticosteroid Regulation Of Metabolic Process Regulation Of Microtubule-based Process Negative Regulation Of Microtubule Polymerization Negative Regulation Of Protein Phosphorylation Positive Regulation Of Kinase Activity Regulation Of Microtubule Polymerization Or Depolymerization Cellular Response To Epinephrine Stimulus Regulation Of Cellular Component Organization System Development Regulation Of Stress-activated MAPK Cascade Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Regulation Of Cellular Protein Metabolic Process Response To Epinephrine RNA Splicing Regulation Of Intracellular Signal Transduction Negative Regulation Of Cell Death Positive Regulation Of Transferase Activity Regulation Of Histone H3-K4 Methylation Regulation Of Kinase Activity Embryo Development Ending In Birth Or Egg Hatching MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Positive Regulation Of Intracellular Signal Transduction
Tagcloud ?		ala78leufsx99 amplified autosomal chinese exons families frequencies harbor heterozygous hong kong missense modify nonpathogenic phe262serfsx59 pigmentosa pro347leu prph2 retina retinitis rho screen screened simplex stranded thirteen truncating woman
Tagcloud (Difference) ?		ala78leufsx99 amplified autosomal chinese exons families frequencies harbor heterozygous hong kong missense modify nonpathogenic phe262serfsx59 pigmentosa pro347leu prph2 retina retinitis rho screen screened simplex stranded thirteen truncating woman
Tagcloud (Intersection) ?