PRPF31 and KHDRBS2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		PRPF31	KHDRBS2
Gene Name		pre-mRNA processing factor 31	KH domain containing, RNA binding, signal transduction associated 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus U2-type Spliceosomal Complex U4 SnRNP U4atac SnRNP Cajal Body Nuclear Speck U4/U6 X U5 Tri-snRNP Complex MLL1 Complex	Nucleus
	Molecular Function	Protein Binding Ribonucleoprotein Complex Binding Poly(A) RNA Binding SnRNP Binding	Protein Binding Poly(A) Binding Poly(U) RNA Binding SH3 Domain Binding SH2 Domain Binding Protein Heterodimerization Activity
	Biological Process	Spliceosomal Tri-snRNP Complex Assembly MRNA Splicing, Via Spliceosome	Transcription, DNA-templated Regulation Of Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS			Protein quantitative trait loci ( 18464913)
Protein-Protein Interactions		55 interactors: AES C1QTNF1 CALCOCO2 CCDC136 CCDC57 CDCA7L CEP70 FANCA GNB2L1 GOLGA2 HNRNPH2 HNRNPK JAKMIP2 KCTD6 KHDRBS2 KHDRBS3 KRT15 KRT40 KRTAP10-1 KRTAP10-3 KRTAP10-8 KRTAP10-9 LDOC1 LURAP1 MID2 MIPOL1 MKRN3 MTUS2 NHP2L1 NOTCH2NL PDE4DIP PHC2 PHF5A PNMA1 PNMA2 PPIH PRICKLE1 PRPF3 PRPF4 PSTPIP1 RBM25 RBM4 RBMY1A1 RBMY1F SIAH1 SSX2IP STX11 TADA2A TFIP11 TMCC2 TP53BP2 TRIM27 TSGA10 ZNF250 ZNF587	29 interactors: AEN CATSPER1 CHTOP CIRBP DOCK2 EWSR1 GRB2 HBZ HNRNPK HNRNPR KHDRBS3 LINC01018 MTA1 NABP1 NCOA5 NPDC1 PRMT1 PRPF31 PRR3 PTK6 RBM3 RBMX SDCBP SPG7 SULT1A3 TYK2 TYMSOS YTHDC1 ZFC3H1
Entrez ID		26121	202559
HPRD ID		05917	13775
Ensembl ID		ENSG00000105618	ENSG00000112232
Uniprot IDs		E7ESA8 F1T0A4 F1T0A5 Q8WWY3	Q5VWX1
PDB IDs		2OZB 3SIU 3SIV
Enriched GO Terms of Interacting Partners?		RNA Splicing MRNA Processing MRNA Metabolic Process RNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Regulation Of Alternative MRNA Splicing, Via Spliceosome Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Regulation Of MRNA Splicing, Via Spliceosome Spermatogenesis Male Gamete Generation Negative Regulation Of Viral Release From Host Cell Regulation Of Gene Expression Regulation Of MRNA Processing Negative Regulation Of Viral Transcription Regulation Of Viral Release From Host Cell Regulation Of RNA Splicing Gamete Generation Protein Trimerization Spliceosomal Complex Disassembly Negative Regulation Of Cardiac Muscle Cell Myoblast Differentiation Reproduction Sexual Reproduction Regulation Of Viral Process Multicellular Organismal Reproductive Process Regulation Of RNA Metabolic Process Multicellular Organism Reproduction Regulation Of Nitrogen Compound Metabolic Process Regulation Of Lipid Transport By Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Interleukin-2 Secretion Positive Regulation Of Aldosterone Secretion Positive Regulation Of CAMP Catabolic Process Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Negative Regulation Of Protein Binding Positive Regulation Of Cell Death Single Organism Reproductive Process Negative Regulation Of Wnt Signaling Pathway Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Hydrogen Peroxide-induced Neuron Death Cellular Component Assembly	RNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Nucleobase-containing Compound Metabolic Process Response To Ionizing Radiation Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA Splicing Cellular Nitrogen Compound Metabolic Process RNA Metabolic Process MRNA Processing Gene Expression Response To Radiation Nitrogen Compound Metabolic Process MRNA Metabolic Process Cellular Process Ribonucleoprotein Complex Assembly Peptidyl-tyrosine Autophosphorylation Response To Abiotic Stimulus Regulation Of Metabolic Process Cellular Metabolic Process Response To Cold Locomotion Positive Regulation Of Metabolic Process Myeloid Dendritic Cell Activation Involved In Immune Response Regulation Of Lipid Transport By Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Protein Autoubiquitination Cell Motility Cell-cell Recognition Cellular Component Assembly Positive Regulation Of Translation Regulation Of Protein Autoubiquitination Membrane Raft Polarization Movement Of Cell Or Subcellular Component Regulation Of Cellular Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Extracellular Vesicular Exosome Assembly Positive Regulation Of Low-density Lipoprotein Particle Receptor Biosynthetic Process Alpha-beta T Cell Proliferation Tyrosine Phosphorylation Of Stat5 Protein Ribonucleoprotein Complex Biogenesis
Tagcloud ?		ala78leufsx99 amplified autosomal chinese exons families frequencies harbor heterozygous hong kong missense modify nonpathogenic phe262serfsx59 pigmentosa pro347leu prph2 retina retinitis rho screen screened simplex stranded thirteen truncating woman
Tagcloud (Difference) ?		ala78leufsx99 amplified autosomal chinese exons families frequencies harbor heterozygous hong kong missense modify nonpathogenic phe262serfsx59 pigmentosa pro347leu prph2 retina retinitis rho screen screened simplex stranded thirteen truncating woman
Tagcloud (Intersection) ?