PRPF31 and CDCA7L

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		PRPF31	CDCA7L
Gene Name		pre-mRNA processing factor 31	cell division cycle associated 7-like
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus U2-type Spliceosomal Complex U4 SnRNP U4atac SnRNP Cajal Body Nuclear Speck U4/U6 X U5 Tri-snRNP Complex MLL1 Complex	Nucleus Nucleolus Cytoplasm
	Molecular Function	Protein Binding Ribonucleoprotein Complex Binding Poly(A) RNA Binding SnRNP Binding	Protein Binding
	Biological Process	Spliceosomal Tri-snRNP Complex Assembly MRNA Splicing, Via Spliceosome	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Positive Regulation Of Cell Proliferation
Pathways
Drugs
Diseases
GWAS			Height ( 20189936)
Protein-Protein Interactions		55 interactors: AES C1QTNF1 CALCOCO2 CCDC136 CCDC57 CDCA7L CEP70 FANCA GNB2L1 GOLGA2 HNRNPH2 HNRNPK JAKMIP2 KCTD6 KHDRBS2 KHDRBS3 KRT15 KRT40 KRTAP10-1 KRTAP10-3 KRTAP10-8 KRTAP10-9 LDOC1 LURAP1 MID2 MIPOL1 MKRN3 MTUS2 NHP2L1 NOTCH2NL PDE4DIP PHC2 PHF5A PNMA1 PNMA2 PPIH PRICKLE1 PRPF3 PRPF4 PSTPIP1 RBM25 RBM4 RBMY1A1 RBMY1F SIAH1 SSX2IP STX11 TADA2A TFIP11 TMCC2 TP53BP2 TRIM27 TSGA10 ZNF250 ZNF587	35 interactors: ABT1 ANKRD11 BEND7 BYSL CARD9 CCDC33 CEP70 CTNNBL1 DAXX DEDD2 EIF4A3 FAM9B ING5 KRTAP10-7 LMO1 MDFI MFAP1 MORN3 MYC NOP2 PPP1R16B PRDM14 PRPF31 SSX2IP STX11 SUV39H1 TADA2A TFPT TRAF3IP3 TRIM42 UBL4A UTP3 VDR ZNF250 ZNF821
Entrez ID		26121	55536
HPRD ID		05917	11481
Ensembl ID		ENSG00000105618	ENSG00000164649
Uniprot IDs		E7ESA8 F1T0A4 F1T0A5 Q8WWY3	A8K8X5 Q96GN5
PDB IDs		2OZB 3SIU 3SIV
Enriched GO Terms of Interacting Partners?		RNA Splicing MRNA Processing MRNA Metabolic Process RNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Regulation Of Alternative MRNA Splicing, Via Spliceosome Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Regulation Of MRNA Splicing, Via Spliceosome Spermatogenesis Male Gamete Generation Negative Regulation Of Viral Release From Host Cell Regulation Of Gene Expression Regulation Of MRNA Processing Negative Regulation Of Viral Transcription Regulation Of Viral Release From Host Cell Regulation Of RNA Splicing Gamete Generation Protein Trimerization Spliceosomal Complex Disassembly Negative Regulation Of Cardiac Muscle Cell Myoblast Differentiation Reproduction Sexual Reproduction Regulation Of Viral Process Multicellular Organismal Reproductive Process Regulation Of RNA Metabolic Process Multicellular Organism Reproduction Regulation Of Nitrogen Compound Metabolic Process Regulation Of Lipid Transport By Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Interleukin-2 Secretion Positive Regulation Of Aldosterone Secretion Positive Regulation Of CAMP Catabolic Process Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Negative Regulation Of Protein Binding Positive Regulation Of Cell Death Single Organism Reproductive Process Negative Regulation Of Wnt Signaling Pathway Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Hydrogen Peroxide-induced Neuron Death Cellular Component Assembly	RNA Metabolic Process RRNA Metabolic Process Nucleobase-containing Compound Metabolic Process RRNA Processing Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Gene Expression Ribonucleoprotein Complex Biogenesis Ribosome Biogenesis Nitrogen Compound Metabolic Process Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Transcription, DNA-templated Chromatin Modification Positive Regulation Of Cell Death RNA Biosynthetic Process Chromatin Organization NcRNA Metabolic Process Regulation Of Stress-activated MAPK Cascade Negative Regulation Of Gene Expression Regulation Of Gene Expression Regulation Of Transcription, DNA-templated Negative Regulation Of Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Chromosome Organization Regulation Of RNA Metabolic Process Regulation Of Apoptotic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Cell Death Cellular Macromolecule Biosynthetic Process Positive Regulation Of JNK Cascade Maturation Of SSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Negative Regulation Of Cellular Metabolic Process Macromolecule Biosynthetic Process Organelle Organization Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Maturation Of SSU-rRNA Activation Of JUN Kinase Activity Regulation Of JNK Cascade Blastocyst Formation Histone Modification Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Ribosomal Small Subunit Biogenesis Regulation Of Metabolic Process
Tagcloud ?		ala78leufsx99 amplified autosomal chinese exons families frequencies harbor heterozygous hong kong missense modify nonpathogenic phe262serfsx59 pigmentosa pro347leu prph2 retina retinitis rho screen screened simplex stranded thirteen truncating woman	able accelerate activate collectively colony constitute conversely division ectopic erk1 hcc hepatocellular inhibits interact knockdown malignant mechanistic myc nude overexpression phenotypes promotes promoting regulate strongly subcutaneous transplantation unclear upregulated
Tagcloud (Difference) ?		ala78leufsx99 amplified autosomal chinese exons families frequencies harbor heterozygous hong kong missense modify nonpathogenic phe262serfsx59 pigmentosa pro347leu prph2 retina retinitis rho screen screened simplex stranded thirteen truncating woman	able accelerate activate collectively colony constitute conversely division ectopic erk1 hcc hepatocellular inhibits interact knockdown malignant mechanistic myc nude overexpression phenotypes promotes promoting regulate strongly subcutaneous transplantation unclear upregulated
Tagcloud (Intersection) ?