PRPF31 and ZNF250

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		PRPF31	ZNF250
Gene Name		pre-mRNA processing factor 31	zinc finger protein 250
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus U2-type Spliceosomal Complex U4 SnRNP U4atac SnRNP Cajal Body Nuclear Speck U4/U6 X U5 Tri-snRNP Complex MLL1 Complex	Nucleus
	Molecular Function	Protein Binding Ribonucleoprotein Complex Binding Poly(A) RNA Binding SnRNP Binding	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Metal Ion Binding
	Biological Process	Spliceosomal Tri-snRNP Complex Assembly MRNA Splicing, Via Spliceosome	Transcription, DNA-templated Regulation Of Transcription, DNA-templated
Pathways			Generic Transcription Pathway
Drugs
Diseases
GWAS
Protein-Protein Interactions		55 interactors: AES C1QTNF1 CALCOCO2 CCDC136 CCDC57 CDCA7L CEP70 FANCA GNB2L1 GOLGA2 HNRNPH2 HNRNPK JAKMIP2 KCTD6 KHDRBS2 KHDRBS3 KRT15 KRT40 KRTAP10-1 KRTAP10-3 KRTAP10-8 KRTAP10-9 LDOC1 LURAP1 MID2 MIPOL1 MKRN3 MTUS2 NHP2L1 NOTCH2NL PDE4DIP PHC2 PHF5A PNMA1 PNMA2 PPIH PRICKLE1 PRPF3 PRPF4 PSTPIP1 RBM25 RBM4 RBMY1A1 RBMY1F SIAH1 SSX2IP STX11 TADA2A TFIP11 TMCC2 TP53BP2 TRIM27 TSGA10 ZNF250 ZNF587	44 interactors: BEGAIN CARD9 CCDC102B CCDC136 CCDC155 CCDC85B CDCA7L CEP44 DPPA2 DVL2 FAM124A GMCL1 GNPTAB GOLGA2 HOOK1 HOOK2 KRT40 KRTAP10-3 KRTAP10-7 KRTAP4-12 LDOC1 LZTS2 MAGOHB MID2 MTUS2 NINL PLEKHF2 PRPF31 SSX2IP SYNE4 TFF1 TMCC2 TNNT1 TNS2 TRIM23 TRIM27 TRIM41 TRIM54 ZBTB8A ZC4H2 ZNF165 ZNF175 ZNF460 ZNF473
Entrez ID		26121	58500
HPRD ID		05917	15758
Ensembl ID		ENSG00000105618	ENSG00000196150
Uniprot IDs		E7ESA8 F1T0A4 F1T0A5 Q8WWY3	B3KNS9 P15622
PDB IDs		2OZB 3SIU 3SIV
Enriched GO Terms of Interacting Partners?		RNA Splicing MRNA Processing MRNA Metabolic Process RNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Regulation Of Alternative MRNA Splicing, Via Spliceosome Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Regulation Of MRNA Splicing, Via Spliceosome Spermatogenesis Male Gamete Generation Negative Regulation Of Viral Release From Host Cell Regulation Of Gene Expression Regulation Of MRNA Processing Negative Regulation Of Viral Transcription Regulation Of Viral Release From Host Cell Regulation Of RNA Splicing Gamete Generation Protein Trimerization Spliceosomal Complex Disassembly Negative Regulation Of Cardiac Muscle Cell Myoblast Differentiation Reproduction Sexual Reproduction Regulation Of Viral Process Multicellular Organismal Reproductive Process Regulation Of RNA Metabolic Process Multicellular Organism Reproduction Regulation Of Nitrogen Compound Metabolic Process Regulation Of Lipid Transport By Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Interleukin-2 Secretion Positive Regulation Of Aldosterone Secretion Positive Regulation Of CAMP Catabolic Process Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Negative Regulation Of Protein Binding Positive Regulation Of Cell Death Single Organism Reproductive Process Negative Regulation Of Wnt Signaling Pathway Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Hydrogen Peroxide-induced Neuron Death Cellular Component Assembly	Lysosome Organization Negative Regulation Of Viral Release From Host Cell Early Endosome To Late Endosome Transport Vacuole Organization Negative Regulation Of Viral Transcription Regulation Of Viral Release From Host Cell Transcription, DNA-templated Endosome To Lysosome Transport RNA Metabolic Process Endosome Organization RNA Biosynthetic Process Chromosome Localization To Nuclear Envelope Involved In Synapsis Gene Expression Lysosomal Transport
Tagcloud ?		ala78leufsx99 amplified autosomal chinese exons families frequencies harbor heterozygous hong kong missense modify nonpathogenic phe262serfsx59 pigmentosa pro347leu prph2 retina retinitis rho screen screened simplex stranded thirteen truncating woman	automated calcein cloned fluorescence genomics initially integrated integrates jun lab luciferase modulating mtt opportunity plasmid prl profiling renilla reporter rnai screen sgol1 stain technologies throughput traf3 traf3ip3 znf306 znf434
Tagcloud (Difference) ?		ala78leufsx99 amplified autosomal chinese exons families frequencies harbor heterozygous hong kong missense modify nonpathogenic phe262serfsx59 pigmentosa pro347leu prph2 retina retinitis rho screened simplex stranded thirteen truncating woman	automated calcein cloned fluorescence genomics initially integrated integrates jun lab luciferase modulating mtt opportunity plasmid prl profiling renilla reporter rnai sgol1 stain technologies throughput traf3 traf3ip3 znf306 znf434
Tagcloud (Intersection) ?		screen