SETBP1 and SET

Number of citations of the paper that reports this interaction (PMID 11231286)
13

Data Source:
HPRD (two hybrid, in vivo)

		SETBP1	SET
Gene Name		SET binding protein 1	SET nuclear proto-oncogene
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Nucleus Nucleoplasm Cytoplasm Endoplasmic Reticulum Cytosol Protein Complex Perinuclear Region Of Cytoplasm
	Molecular Function	DNA Binding	DNA Binding Protein Phosphatase Inhibitor Activity Protein Binding Protein Phosphatase Type 2A Regulator Activity Histone Binding
	Biological Process		Mitotic Cell Cycle DNA Replication Nucleosome Assembly Nucleosome Disassembly Nucleocytoplasmic Transport Gene Expression Negative Regulation Of Histone Acetylation Negative Regulation Of Catalytic Activity Negative Regulation Of Neuron Apoptotic Process Negative Regulation Of Transcription, DNA-templated Regulation Of Catalytic Activity
Pathways			Regulation of mRNA stability by proteins that bind AU-rich elements Mitotic Prophase Condensation of Prophase Chromosomes HuR stabilizes mRNA Cell Cycle, Mitotic M Phase
Drugs
Diseases
GWAS		Male-pattern baldness ( 22693459) Ventricular conduction ( 21076409)	Eating disorders (purging via substances) ( 23568457)
Protein-Protein Interactions		11 interactors: APP KIAA1147 LRRC37A11P PLEKHF2 SET SPANXA1 SPANXC SPANXD SUMO1P1 UBE2I YAF2	51 interactors: ANP32A APEX1 APP CALM1 CDK5 CDK5R1 CDKN1A CHAF1A CHRM2 CHRM3 ELAVL1 ELF4 EP300 FAM111B FOS GZMA GZMK HDAC1 HIST1H2BA HIST1H3A HIST2H4A HIST3H3 HIST4H4 HMGB2 IRF1 JUNB KLF5 KMT2A MDM2 MEOX2 MTERF1 NME1 NUCB1 NUPR1 PIK3CG PPP2CA PPP2R1B PRKAR1A PTMA RAC1 SDCBP SETBP1 SGOL1 TAF1A TERF1 TERF2 TERF2IP THAP7 TP53 TREX1 UCHL5
Entrez ID		26040	6418
HPRD ID		10224	09023
Ensembl ID		ENSG00000152217	ENSG00000119335
Uniprot IDs		Q9Y6X0	Q01105 Q5VXV3
PDB IDs			2E50
Enriched GO Terms of Interacting Partners?		Positive Regulation Of SUMO Transferase Activity Regulation Of Receptor Activity Synaptic Growth At Neuromuscular Junction	Negative Regulation Of Cellular Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process DNA Metabolic Process Regulation Of Cell Cycle Cellular Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Negative Regulation Of Biosynthetic Process Nitrogen Compound Metabolic Process Regulation Of Gene Expression Chromosome Organization Regulation Of Transcription, DNA-templated Cell Death Death Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Metabolic Process Gene Expression Telomere Maintenance Developmental Process Regulation Of RNA Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Apoptotic Process Programmed Cell Death Regulation Of Cell Cycle Process Cellular Metabolic Process DNA Replication-dependent Nucleosome Assembly Cell Cycle Transcription, DNA-templated Organelle Organization Regulation Of Gene Expression, Epigenetic Blood Coagulation Positive Regulation Of Protein Metabolic Process Chromatin Assembly RNA Biosynthetic Process Cellular Component Assembly Hemostasis Chromatin Organization Negative Regulation Of Cell Cycle Anatomical Structure Development Cellular Response To Growth Factor Stimulus Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Body Fluid Levels Negative Regulation Of Transcription, DNA-templated Response To Growth Factor Negative Regulation Of Gene Expression
Tagcloud ?		1155insttgtc accuracy allele asxl1 calr carried cml cnl criteria csf3r diagnostic differential gammopathy jak2 leukocytosis mgus monoclonal mutations neutrophilic observe protocol retrospectively reviewed sequenced significance suspected twelve uncertain v617f	already assessing cognition cognitive cogs computation correlating costs cps deterioration easy estimate exam global inasmuch mds meaningful mental mini minimum msd quite residents scale scales simple slightly straightforward substantially utility
Tagcloud (Difference) ?		1155insttgtc accuracy allele asxl1 calr carried cml cnl criteria csf3r diagnostic differential gammopathy jak2 leukocytosis mgus monoclonal mutations neutrophilic observe protocol retrospectively reviewed sequenced significance suspected twelve uncertain v617f	already assessing cognition cognitive cogs computation correlating costs cps deterioration easy estimate exam global inasmuch mds meaningful mental mini minimum msd quite residents scale scales simple slightly straightforward substantially utility
Tagcloud (Intersection) ?