UPF2 and UPF1

  • Number of citations of the paper that reports this interaction (PMID 11073994)
  • 47
  • Data Source:
  • HPRD (in vivo, two hybrid, in vitro)

UPF2

UPF1

Gene Name UPF2 regulator of nonsense transcripts homolog (yeast) UPF1 regulator of nonsense transcripts homolog (yeast)
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Prostate cancer (gene x gene interaction) ( 22219177)
Protein-Protein Interactions 75 interactors: ABCF2 AGPAT1 ART4 ATP1B3 BLM CALR CENPU CIZ1 COMTD1 CYBA DCP1B DCP2 DPF2 E4F1 EIF1 EIF4A1 EIF4G1 ENO1 EXOSC1 EXOSC10 EXOSC4 EXOSC6 EXOSC8 GADD45GIP1 GLTSCR2 HBZ HMGA1 HS3ST3A1 HSF2BP ITGB1 KRT18 LDHA LSM1 MAP1A MAP1LC3B MIF MRPL40 MTERF3 MYB NDUFA7 NOB1 NOMO1 PHB2 PITX1 PUF60 RNPS1 RPL13 RPL5 RPL8 RPS15 RPS25 RPS6 RPS7 RRP7A RSRC2 SERBP1 SERF2 SKIV2L2 SMG1 SUMO3 TK1 TNNI2 TOP3B TUBB2A TYMS UPF1 UPF3B WNK1 XRN1 XRN2 ZBTB48 ZFP36 ZGPAT ZNF408 ZNF44 31 interactors: ABHD16A ACSS2 ATR CSNK2B DCP1A DCP2 DXO EIF3A EIF3B EIF4A3 EXOSC2 EXOSC4 GNPTG GSPT2 HIRA LSM8 NADSYN1 NDRG1 NDUFB10 PLEKHA5 PLEKHB2 POLR2A RHOXF2 RPRD2 SMG1 SMG5 STAU1 UPF2 UPF3A UPF3B XRN1
Entrez ID 26019 5976
HPRD ID 10405 03254
Ensembl ID ENSG00000151461 ENSG00000005007
Uniprot IDs Q9HAU5 Q92900
PDB IDs 1UW4 2WJV 2GJK 2GK6 2GK7 2IYK 2WJV 2WJY 2XZO 2XZP
Enriched GO Terms of Interacting Partners?
Tagcloud ?
achieves  bridge  cenp  centromere  centromeres  counteracted  decay  delocalization  dispensable  ebs1  extragenic  fission  interphase  massive  mis16  mis18  mis19  mis20  missegregation  pombe  recruiting  schizosaccharomyces  segregation  sense  snf  snf22  snf5  sol1  swi 
aav9  adeno  als  amyotrophic  cord  decay  empty  exerts  forelimb  green  helps  implicate  mycupf1  nmd  nonsense  otherwise  paralysis  quadriplegic  recapitulate  reproducible  respective  spinal  tdp  titrated  transactive  twofold  upframeshift  validate  vector 
Tagcloud (Difference) ?
achieves  bridge  cenp  centromere  centromeres  counteracted  delocalization  dispensable  ebs1  extragenic  fission  interphase  massive  mis16  mis18  mis19  mis20  missegregation  pombe  recruiting  schizosaccharomyces  segregation  sense  snf  snf22  snf5  sol1  swi 
aav9  adeno  als  amyotrophic  cord  empty  exerts  forelimb  green  helps  implicate  mycupf1  nmd  nonsense  otherwise  paralysis  quadriplegic  recapitulate  reproducible  respective  spinal  tdp  titrated  transactive  twofold  upframeshift  validate  vector 
Tagcloud (Intersection) ?
decay