UPF2 and ATP1B3

Number of citations of the paper that reports this interaction (PMID 15231747)
44

Data Source:
BioGRID (two hybrid)

		UPF2	ATP1B3
Gene Name		UPF2 regulator of nonsense transcripts homolog (yeast)	ATPase, Na+/K+ transporting, beta 3 polypeptide
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Exon-exon Junction Complex Perinuclear Region Of Cytoplasm	Plasma Membrane Sodium:potassium-exchanging ATPase Complex Caveola Melanosome Extracellular Vesicular Exosome
	Molecular Function	RNA Binding Protein Binding	ATPase Activator Activity Sodium:potassium-exchanging ATPase Activity ATPase Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Liver Development MRNA Export From Nucleus Gene Expression Organ Regeneration	Transport Cellular Sodium Ion Homeostasis Blood Coagulation Potassium Ion Import Cellular Potassium Ion Homeostasis Positive Regulation Of ATPase Activity Ion Transmembrane Transport Sodium Ion Export From Cell Protein Stabilization Leukocyte Migration Transmembrane Transport Protein Localization To Plasma Membrane Membrane Repolarization Positive Regulation Of Potassium Ion Transmembrane Transporter Activity Positive Regulation Of Sodium Ion Export From Cell Positive Regulation Of Potassium Ion Import
Pathways		Nonsense-Mediated Decay (NMD) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)	Ion transport by P-type ATPases Ion channel transport Basigin interactions Cell surface interactions at the vascular wall
Drugs
Diseases
GWAS		Prostate cancer (gene x gene interaction) ( 22219177)
Protein-Protein Interactions		75 interactors: ABCF2 AGPAT1 ART4 ATP1B3 BLM CALR CENPU CIZ1 COMTD1 CYBA DCP1B DCP2 DPF2 E4F1 EIF1 EIF4A1 EIF4G1 ENO1 EXOSC1 EXOSC10 EXOSC4 EXOSC6 EXOSC8 GADD45GIP1 GLTSCR2 HBZ HMGA1 HS3ST3A1 HSF2BP ITGB1 KRT18 LDHA LSM1 MAP1A MAP1LC3B MIF MRPL40 MTERF3 MYB NDUFA7 NOB1 NOMO1 PHB2 PITX1 PUF60 RNPS1 RPL13 RPL5 RPL8 RPS15 RPS25 RPS6 RPS7 RRP7A RSRC2 SERBP1 SERF2 SKIV2L2 SMG1 SUMO3 TK1 TNNI2 TOP3B TUBB2A TYMS UPF1 UPF3B WNK1 XRN1 XRN2 ZBTB48 ZFP36 ZGPAT ZNF408 ZNF44	5 interactors: BARD1 BRCA1 PAXIP1 UPF2 USP4
Entrez ID		26019	483
HPRD ID		10405	03521
Ensembl ID		ENSG00000151461	ENSG00000069849
Uniprot IDs		Q9HAU5	B7Z1N7 P54709
PDB IDs		1UW4 2WJV
Enriched GO Terms of Interacting Partners?		Nuclear-transcribed MRNA Catabolic Process RNA Catabolic Process MRNA Catabolic Process Aromatic Compound Catabolic Process MRNA Metabolic Process Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Cellular Macromolecule Catabolic Process Gene Expression Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay RRNA Metabolic Process Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Catabolic Process Histone MRNA Catabolic Process RRNA Processing Macromolecule Biosynthetic Process Cellular Macromolecule Biosynthetic Process Translational Initiation Viral Process Ribosome Biogenesis Biosynthetic Process Histone MRNA Metabolic Process Cellular Metabolic Process Translational Termination Protein Complex Disassembly Translational Elongation RNA Biosynthetic Process Ribonucleoprotein Complex Biogenesis Cellular Protein Complex Disassembly Viral Transcription NcRNA Metabolic Process SRP-dependent Cotranslational Protein Targeting To Membrane Cotranslational Protein Targeting To Membrane Protein Targeting To ER Establishment Of Protein Localization To Endoplasmic Reticulum Protein Localization To Endoplasmic Reticulum Viral Life Cycle Cytoplasmic Transport Metabolic Process Establishment Of Protein Localization To Membrane Translation Protein Targeting To Membrane Nuclear MRNA Surveillance Protein Localization To Membrane	Protein K6-linked Ubiquitination Positive Regulation Of Histone H3-K4 Methylation Positive Regulation Of Histone Acetylation Regulation Of Histone H3-K4 Methylation Regulation Of Protein Ubiquitination Positive Regulation Of Peptidyl-lysine Acetylation Positive Regulation Of Protein Acetylation Positive Regulation Of Histone Methylation Regulation Of Histone Acetylation Regulation Of Histone Methylation Positive Regulation Of Histone Modification DNA Damage Response, Signal Transduction By P53 Class Mediator DNA Repair Signal Transduction In Response To DNA Damage Positive Regulation Of Histone H4-K20 Methylation Positive Regulation Of Histone H3-K36 Methylation Positive Regulation Of Histone H4-K16 Acetylation Signal Transduction By P53 Class Mediator Regulation Of Histone Modification Nucleobase-containing Compound Metabolic Process Positive Regulation Of Protein Ubiquitination Regulation Of Protein Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Response To Ionizing Radiation Positive Regulation Of DNA Metabolic Process Negative Regulation Of MRNA 3'-end Processing Positive Regulation Of Histone H3-K9 Acetylation Cellular Response To DNA Damage Stimulus Cellular Nitrogen Compound Metabolic Process Protein Polyubiquitination Positive Regulation Of Histone H4 Acetylation Negative Regulation Of Histone H3-K4 Methylation Nitrogen Compound Metabolic Process Regulation Of Chromosome Organization DNA Metabolic Process DNA Recombination Cellular Response To Indole-3-methanol Negative Regulation Of Centriole Replication Positive Regulation Of Protein Metabolic Process Negative Regulation Of Protein Export From Nucleus Dosage Compensation By Inactivation Of X Chromosome Cellular Protein Modification Process Negative Regulation Of Histone H3-K9 Methylation Positive Regulation Of Histone H3-K9 Methylation Dosage Compensation Chorion Development Regulation Of Histone H3-K9 Acetylation Cellular Response To Stress Regulation Of Centriole Replication
Tagcloud ?		achieves bridge cenp centromere centromeres counteracted decay delocalization dispensable ebs1 extragenic fission interphase massive mis16 mis18 mis19 mis20 missegregation pombe recruiting schizosaccharomyces segregation sense snf snf22 snf5 sol1 swi	a2ld1 aide art assisted bioinformatics blotting diagnoses discussion fbxo2 identity idiopathic infertility isobaric men plex pregnancy proteomic proteomics reproductive select semen spectrometry sperm spermatozoa tag tandem tmt unsuccessful whose
Tagcloud (Difference) ?		achieves bridge cenp centromere centromeres counteracted decay delocalization dispensable ebs1 extragenic fission interphase massive mis16 mis18 mis19 mis20 missegregation pombe recruiting schizosaccharomyces segregation sense snf snf22 snf5 sol1 swi	a2ld1 aide art assisted bioinformatics blotting diagnoses discussion fbxo2 identity idiopathic infertility isobaric men plex pregnancy proteomic proteomics reproductive select semen spectrometry sperm spermatozoa tag tandem tmt unsuccessful whose
Tagcloud (Intersection) ?