UPF2 and ART4

Number of citations of the paper that reports this interaction (PMID 15231747)
44

Data Source:
BioGRID (two hybrid)

		UPF2	ART4
Gene Name		UPF2 regulator of nonsense transcripts homolog (yeast)	ADP-ribosyltransferase 4 (Dombrock blood group)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Exon-exon Junction Complex Perinuclear Region Of Cytoplasm	Plasma Membrane Membrane Anchored Component Of Membrane
	Molecular Function	RNA Binding Protein Binding	NAD(P)+-protein-arginine ADP-ribosyltransferase Activity
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Liver Development MRNA Export From Nucleus Gene Expression Organ Regeneration	Protein ADP-ribosylation Arginine Metabolic Process
Pathways		Nonsense-Mediated Decay (NMD) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS		Prostate cancer (gene x gene interaction) ( 22219177)
Protein-Protein Interactions		75 interactors: ABCF2 AGPAT1 ART4 ATP1B3 BLM CALR CENPU CIZ1 COMTD1 CYBA DCP1B DCP2 DPF2 E4F1 EIF1 EIF4A1 EIF4G1 ENO1 EXOSC1 EXOSC10 EXOSC4 EXOSC6 EXOSC8 GADD45GIP1 GLTSCR2 HBZ HMGA1 HS3ST3A1 HSF2BP ITGB1 KRT18 LDHA LSM1 MAP1A MAP1LC3B MIF MRPL40 MTERF3 MYB NDUFA7 NOB1 NOMO1 PHB2 PITX1 PUF60 RNPS1 RPL13 RPL5 RPL8 RPS15 RPS25 RPS6 RPS7 RRP7A RSRC2 SERBP1 SERF2 SKIV2L2 SMG1 SUMO3 TK1 TNNI2 TOP3B TUBB2A TYMS UPF1 UPF3B WNK1 XRN1 XRN2 ZBTB48 ZFP36 ZGPAT ZNF408 ZNF44	2 interactors: APP UPF2
Entrez ID		26019	420
HPRD ID		10405	04364
Ensembl ID		ENSG00000151461
Uniprot IDs		Q9HAU5	Q93070
PDB IDs		1UW4 2WJV
Enriched GO Terms of Interacting Partners?		Nuclear-transcribed MRNA Catabolic Process RNA Catabolic Process MRNA Catabolic Process Aromatic Compound Catabolic Process MRNA Metabolic Process Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Cellular Macromolecule Catabolic Process Gene Expression Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay RRNA Metabolic Process Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Catabolic Process Histone MRNA Catabolic Process RRNA Processing Macromolecule Biosynthetic Process Cellular Macromolecule Biosynthetic Process Translational Initiation Viral Process Ribosome Biogenesis Biosynthetic Process Histone MRNA Metabolic Process Cellular Metabolic Process Translational Termination Protein Complex Disassembly Translational Elongation RNA Biosynthetic Process Ribonucleoprotein Complex Biogenesis Cellular Protein Complex Disassembly Viral Transcription NcRNA Metabolic Process SRP-dependent Cotranslational Protein Targeting To Membrane Cotranslational Protein Targeting To Membrane Protein Targeting To ER Establishment Of Protein Localization To Endoplasmic Reticulum Protein Localization To Endoplasmic Reticulum Viral Life Cycle Cytoplasmic Transport Metabolic Process Establishment Of Protein Localization To Membrane Translation Protein Targeting To Membrane Nuclear MRNA Surveillance Protein Localization To Membrane	Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition MRNA Metabolic Process Neuron Remodeling Cellular Copper Ion Homeostasis Copper Ion Homeostasis Suckling Behavior Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Mating Behavior Endoplasmic Reticulum Calcium Ion Homeostasis Neuron Recognition RNA Polyadenylation Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Ionotropic Glutamate Receptor Signaling Pathway Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G2/M Phase Transition Intracellular Transport Axon Cargo Transport Mating Neuromuscular Junction Development Positive Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Phase Transition Neuron Apoptotic Process Regulation Of Protein Tyrosine Kinase Activity Visual Learning Glutamate Receptor Signaling Pathway Visual Behavior Neuron Death MRNA Export From Nucleus Platelet Degranulation RNA Export From Nucleus Organ Regeneration Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Neuromuscular Process Controlling Balance Synapse Assembly MRNA 3'-end Processing Regulation Of ERBB Signaling Pathway Associative Learning Developmental Cell Growth Establishment Of Localization In Cell Regulation Of Synapse Structure Or Activity Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Feeding Behavior
Tagcloud ?		achieves bridge cenp centromere centromeres counteracted decay delocalization dispensable ebs1 extragenic fission interphase massive mis16 mis18 mis19 mis20 missegregation pombe recruiting schizosaccharomyces segregation sense snf snf22 snf5 sol1 swi	arrestin art1 art7 bar1 cognate degrading detrimental galpha gbetagamma gpa1 gpcr gpcrs heterotrimeric initiates internalization ldb19 pheromone ppxy recruit rod1 rog3 rsp5 sst2 ste18 ste2 ste4 ubiquitinylation yck1 yck2
Tagcloud (Difference) ?		achieves bridge cenp centromere centromeres counteracted decay delocalization dispensable ebs1 extragenic fission interphase massive mis16 mis18 mis19 mis20 missegregation pombe recruiting schizosaccharomyces segregation sense snf snf22 snf5 sol1 swi	arrestin art1 art7 bar1 cognate degrading detrimental galpha gbetagamma gpa1 gpcr gpcrs heterotrimeric initiates internalization ldb19 pheromone ppxy recruit rod1 rog3 rsp5 sst2 ste18 ste2 ste4 ubiquitinylation yck1 yck2
Tagcloud (Intersection) ?