UPF2 and DPF2

Number of citations of the paper that reports this interaction (PMID 15231747)
44

Data Source:
BioGRID (two hybrid)

		UPF2	DPF2
Gene Name		UPF2 regulator of nonsense transcripts homolog (yeast)	D4, zinc and double PHD fingers family 2
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Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Exon-exon Junction Complex Perinuclear Region Of Cytoplasm	Nuclear Chromatin Nucleoplasm Cytoplasm Centrosome Intracellular Membrane-bounded Organelle
	Molecular Function	RNA Binding Protein Binding	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Zinc Ion Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Liver Development MRNA Export From Nucleus Gene Expression Organ Regeneration	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Apoptotic Process Apoptotic Signaling Pathway
Pathways		Nonsense-Mediated Decay (NMD) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS		Prostate cancer (gene x gene interaction) ( 22219177)
Protein-Protein Interactions		75 interactors: ABCF2 AGPAT1 ART4 ATP1B3 BLM CALR CENPU CIZ1 COMTD1 CYBA DCP1B DCP2 DPF2 E4F1 EIF1 EIF4A1 EIF4G1 ENO1 EXOSC1 EXOSC10 EXOSC4 EXOSC6 EXOSC8 GADD45GIP1 GLTSCR2 HBZ HMGA1 HS3ST3A1 HSF2BP ITGB1 KRT18 LDHA LSM1 MAP1A MAP1LC3B MIF MRPL40 MTERF3 MYB NDUFA7 NOB1 NOMO1 PHB2 PITX1 PUF60 RNPS1 RPL13 RPL5 RPL8 RPS15 RPS25 RPS6 RPS7 RRP7A RSRC2 SERBP1 SERF2 SKIV2L2 SMG1 SUMO3 TK1 TNNI2 TOP3B TUBB2A TYMS UPF1 UPF3B WNK1 XRN1 XRN2 ZBTB48 ZFP36 ZGPAT ZNF408 ZNF44	14 interactors: ESRRA ESRRB ESRRG FHL2 HIST1H3A HIST3H3 LDOC1 LNX1 NFKB2 REL RELB SMARCB1 UPF2 ZNF212
Entrez ID		26019	5977
HPRD ID		10405	03394
Ensembl ID		ENSG00000151461	ENSG00000133884
Uniprot IDs		Q9HAU5	B4DT58 J3KMZ8 Q92785
PDB IDs		1UW4 2WJV	3IUF
Enriched GO Terms of Interacting Partners?		Nuclear-transcribed MRNA Catabolic Process RNA Catabolic Process MRNA Catabolic Process Aromatic Compound Catabolic Process MRNA Metabolic Process Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Cellular Macromolecule Catabolic Process Gene Expression Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay RRNA Metabolic Process Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Catabolic Process Histone MRNA Catabolic Process RRNA Processing Macromolecule Biosynthetic Process Cellular Macromolecule Biosynthetic Process Translational Initiation Viral Process Ribosome Biogenesis Biosynthetic Process Histone MRNA Metabolic Process Cellular Metabolic Process Translational Termination Protein Complex Disassembly Translational Elongation RNA Biosynthetic Process Ribonucleoprotein Complex Biogenesis Cellular Protein Complex Disassembly Viral Transcription NcRNA Metabolic Process SRP-dependent Cotranslational Protein Targeting To Membrane Cotranslational Protein Targeting To Membrane Protein Targeting To ER Establishment Of Protein Localization To Endoplasmic Reticulum Protein Localization To Endoplasmic Reticulum Viral Life Cycle Cytoplasmic Transport Metabolic Process Establishment Of Protein Localization To Membrane Translation Protein Targeting To Membrane Nuclear MRNA Surveillance Protein Localization To Membrane	Regulation Of Transcription From RNA Polymerase II Promoter Gene Expression Nucleobase-containing Compound Metabolic Process Positive Regulation Of Transcription, DNA-templated Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Biosynthetic Process Transcription, DNA-templated RNA Metabolic Process RNA Biosynthetic Process Nitrogen Compound Metabolic Process NIK/NF-kappaB Signaling Intracellular Receptor Signaling Pathway I-kappaB Kinase/NF-kappaB Signaling Transcription From RNA Polymerase II Promoter Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Transcription, DNA-templated Regulation Of RNA Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Steroid Hormone Mediated Signaling Pathway Positive Regulation Of Cellular Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Gene Expression Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Hormone-mediated Signaling Pathway Transcription Initiation From RNA Polymerase II Promoter Cellular Metabolic Process Cellular Response To Steroid Hormone Stimulus Positive Regulation Of Metabolic Process Response To Organic Substance DNA-templated Transcription, Initiation Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Follicular Dendritic Cell Differentiation Trophectodermal Cell Proliferation Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Cellular Response To Organic Cyclic Compound Cellular Response To Lipid Blastocyst Development
Tagcloud ?		achieves bridge cenp centromere centromeres counteracted decay delocalization dispensable ebs1 extragenic fission interphase massive mis16 mis18 mis19 mis20 missegregation pombe recruiting schizosaccharomyces segregation sense snf snf22 snf5 sol1 swi	1alpha acetylated androgen associating baf45d biogenesis coactivator coactivators converted derepressed enhances err erralpha fingers hdac1 hela myoblast peroxisome pgc phd proliferator purification recognizing repressive repressor stably steroid superfamily transactivation
Tagcloud (Difference) ?		achieves bridge cenp centromere centromeres counteracted decay delocalization dispensable ebs1 extragenic fission interphase massive mis16 mis18 mis19 mis20 missegregation pombe recruiting schizosaccharomyces segregation sense snf snf22 snf5 sol1 swi	1alpha acetylated androgen associating baf45d biogenesis coactivator coactivators converted derepressed enhances err erralpha fingers hdac1 hela myoblast peroxisome pgc phd proliferator purification recognizing repressive repressor stably steroid superfamily transactivation
Tagcloud (Intersection) ?