MCM9 and MESD

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MCM9	MESD
Description		minichromosome maintenance 9 homologous recombination repair factor	mesoderm development LRP chaperone
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Chromosome MCM Complex MCM8-MCM9 Complex	Endoplasmic Reticulum Plasma Membrane
	Molecular Function	Nucleotide Binding DNA Binding DNA Helicase Activity Chromatin Binding Single-stranded DNA Binding Helicase Activity Protein Binding ATP Binding Hydrolase Activity ATP Hydrolysis Activity Single-stranded DNA Helicase Activity Enzyme Binding MutLbeta Complex Binding MutSalpha Complex Binding MutSbeta Complex Binding Protein-containing Complex Binding	Protein Binding Identical Protein Binding Protein Folding Chaperone Low-density Lipoprotein Particle Receptor Binding
	Biological Process	Double-strand Break Repair Via Homologous Recombination DNA Replication DNA Repair DNA Damage Response Gamete Generation Female Gamete Generation Recombinational Interstrand Cross-link Repair Mismatch Repair Involved In Maintenance Of Fidelity Involved In DNA-dependent DNA Replication Protein Localization To Chromatin	Ossification Protein Folding Phagocytosis Mesoderm Development Wnt Signaling Pathway Positive Regulation Of Wnt Signaling Pathway Protein Localization To Cell Surface Protein Localization To Plasma Membrane Positive Regulation Of Skeletal Muscle Acetylcholine-gated Channel Clustering
Pathways
Drugs
Diseases
GWAS		Depression in smokers ( 30219690) Homeostasis model assessment of insulin resistance ( 33381925) Household income (MTAG) ( 31844048) Mean platelet volume ( 32888494) Metabolite levels ( 23823483) Systolic blood pressure ( 30224653) Working memory ( 31598132)
Interacting Genes		1 interacting genes: MESD	78 interacting genes: - ABCG8 ABITRAM ACBD7 AKIRIN2 AKNAD1 AKT1 APP ARB2A ASH2L ATP6V1E1 ATP6V1E2 BORCS8 BORCS8-MEF2B BRD4 C17orf75 CDR2L CENATAC CENPH CHCHD1 CLP1 CNOT9 COL10A1 COL1A2 COX14 COX5A CUTC CYP4F11 DDX6 ENKD1 FAM13C FARS2 FCER1A GEM GOLGA7 GPKOW GTPBP3 H2AB2 H2AB3 HSBP1L1 IGF1 KLHL20 KPNB1 LCE1A LRP5 LY96 MAGEB4 MAP1LC3B MAPDA MCM9 MELTF MKNK2 MRM1 MTNR1A NAA35 NRDE2 PMF1 PSMA5 QARS1 RCOR3 RFC3 SLC6A20 SMARCB1 SNX5 SNX7 TEKTL1 TEX12 TEX48 TPM2 TREX2 TRMT2A TTC21A TTC23 TYMP UBQLN1 ZNF493 ZNF827 ZNF844
Entrez ID		254394	23184
HPRD ID		17472	12129
Ensembl ID		ENSG00000111877	ENSG00000117899
Uniprot IDs		A0A0S2Z662 Q9NXL9	Q14696
PDB IDs		7DPD 7WI7 7YOX 8S91 8S92 8S94
Enriched GO Terms of Interacting Partners?		Regulation Of Skeletal Muscle Acetylcholine-gated Channel Clustering Positive Regulation Of Skeletal Muscle Acetylcholine-gated Channel Clustering Positive Regulation Of Receptor Clustering Regulation Of Receptor Clustering Protein Localization To Cell Surface Low-density Lipoprotein Particle Receptor Binding Mesoderm Development Protein Folding Chaperone Positive Regulation Of Protein Localization To Membrane Phagocytosis Ossification Positive Regulation Of Wnt Signaling Pathway Regulation Of Protein Localization To Membrane Protein Localization To Plasma Membrane Protein Folding Protein Localization To Cell Periphery	Protein Binding Proton-transporting Two-sector ATPase Complex, Catalytic Domain
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