ABL1 and GRB10

  • Number of citations of the paper that reports this interaction (PMID 9006901)
  • 17
  • Data Source:
  • BioGRID (affinity chromatography technology, pull down)

ABL1

GRB10

Gene Name ABL proto-oncogene 1, non-receptor tyrosine kinase growth factor receptor-bound protein 10
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Acute lymphoblastic leukemia (childhood) ( 23512250)
  • Bone mineral density ( 22504420)
  • Fasting glucose-related traits (interaction with BMI) ( 22581228)
  • Systemic sclerosis ( 21779181)
Protein-Protein Interactions 145 interactors: ABI1 ABI2 ABL2 ACTA1 ADAM15 ANKRA2 APBB1 APP ARHGAP17 ATM ATR BCAR1 BCR BIN1 BRCA1 BTK C3 CABLES1 CABLES2 CASP9 CAT CAV1 CBL CCND2 CD19 CDK1 CDK5 CDKN1B CDON CREB1 CRK CRKL CTNND2 DDB1 DDB2 DOK1 DOK2 DOK3 EGFR ENAH EP300 EPHA3 EPHB2 ERBB2 ERBB3 ERBB4 EVL GPX1 GRB10 GRB2 GRIN2D GTF2F1 HCK HUWE1 INPPL1 JAK1 JAK2 JUN KIT LATS2 MAP4K1 MAP4K5 MAPT MAVS MBP MDM2 MICAL1 MUC1 NCK1 NCOA3 NCSTN NEDD4 NEDD4L NEDD9 NFKBIA NTRK1 PAG1 PAK2 PDE4D PIK3R1 PLCG1 PLSCR1 POLR2A PRDX1 PRKD1 PRKDC PSMA7 PSTPIP1 PTPN12 PTPN18 PTPN6 PXN RAD51 RAD52 RAD9A RAN RAPGEF1 RASA1 RB1 RFX1 RIN1 ROBO1 ROS1 RYBP SFN SH3BP1 SH3BP2 SHD SHE SLC9A2 SORBS1 SORBS2 SORBS3 SOS2 SPRR2A SPTA1 SPTAN1 SRC SRPK2 ST5 STUB1 TERT TOPBP1 TP53 TP73 TRAF6 TUB UBC VAV1 WASF1 WASF2 WASL WRNIP1 XPO1 XRCC6 YAP1 YTHDC1 YWHAB YWHAE YWHAG YWHAH YWHAQ YWHAZ ZAP70 ZDHHC16 30 interactors: ABL1 AKT1 APP BCR DOK1 EGFR ELK1 EPHB1 FYN GHR GIGYF1 GIGYF2 IGF1R INSR IRS1 JAK2 KDR KIT MAP2K1 MAP3K14 MAPK1 MEGF10 NEDD4 NOA1 PDGFRB RAF1 RET RQCD1 SRC ZDHHC17
Entrez ID 25 2887
HPRD ID 01809 03312
Ensembl ID ENSG00000097007 ENSG00000106070
Uniprot IDs P00519 Q59FK4 Q13322
PDB IDs 1AB2 1ABL 1AWO 1BBZ 1JU5 1OPL 1ZZP 2ABL 2E2B 2F4J 2FO0 2G1T 2G2F 2G2H 2G2I 2GQG 2HIW 2HYY 2HZ0 2HZ4 2HZI 2O88 2V7A 3CS9 3EG0 3EG1 3EG2 3EG3 3EGU 3K2M 3PYY 3QRI 3QRJ 3QRK 3T04 3UE4 3UYO 1NRV 3HK0
Enriched GO Terms of Interacting Partners?
Tagcloud ?
aba  abi1  abscisic  advantage  arabidopsis  assayed  character  contrary  copies  defense  dormancy  drought  implicates  lap  le25  meja  mrnas  pin2  proteinase  requisite  seed  signalling  tas14  tomato  transcripts  transformants  wilty  wound  wounding 
becomes  carries  cytokine  driven  effector  emerging  exert  fashion  fos  grbir  homology  hybrid  insights  interacting  looked  member  nonreceptor  obscure  phosphorylated  pleckstrin  profoundly  ptks  subfamily  subset  suppresses  syk  tec  tips  turned 
Tagcloud (Difference) ?
aba  abi1  abscisic  advantage  arabidopsis  assayed  character  contrary  copies  defense  dormancy  drought  implicates  lap  le25  meja  mrnas  pin2  proteinase  requisite  seed  signalling  tas14  tomato  transcripts  transformants  wilty  wound  wounding 
becomes  carries  cytokine  driven  effector  emerging  exert  fashion  fos  grbir  homology  hybrid  insights  interacting  looked  member  nonreceptor  obscure  phosphorylated  pleckstrin  profoundly  ptks  subfamily  subset  suppresses  syk  tec  tips  turned 
Tagcloud (Intersection) ?