GRB10 and NOA1

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		GRB10	NOA1
Gene Name		growth factor receptor-bound protein 10	nitric oxide associated 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane	Mitochondrion Extrinsic Component Of Mitochondrial Inner Membrane
	Molecular Function	SH3/SH2 Adaptor Activity Insulin Receptor Binding Protein Binding	GTPase Activity Protein Binding GTP Binding Poly(A) RNA Binding
	Biological Process	Insulin Receptor Signaling Pathway Negative Regulation Of Wnt Signaling Pathway Positive Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Response To Insulin Negative Regulation Of Phosphorylation Positive Regulation Of Phosphorylation Negative Regulation Of Glycogen Biosynthetic Process Negative Regulation Of Glucose Import Negative Regulation Of Insulin Receptor Signaling Pathway Insulin-like Growth Factor Receptor Signaling Pathway	Apoptotic Process Regulation Of Cell Death Mitochondrial Translation Ribosome Biogenesis Regulation Of Cellular Respiration
Pathways		Signaling by SCF-KIT Insulin receptor signalling cascade IRS activation Signal attenuation IRS-related events SHC-related events SHC activation Signaling by Insulin receptor
Drugs
Diseases
GWAS		Acute lymphoblastic leukemia (childhood) ( 23512250) Bone mineral density ( 22504420) Fasting glucose-related traits (interaction with BMI) ( 22581228) Systemic sclerosis ( 21779181)
Protein-Protein Interactions		30 interactors: ABL1 AKT1 APP BCR DOK1 EGFR ELK1 EPHB1 FYN GHR GIGYF1 GIGYF2 IGF1R INSR IRS1 JAK2 KDR KIT MAP2K1 MAP3K14 MAPK1 MEGF10 NEDD4 NOA1 PDGFRB RAF1 RET RQCD1 SRC ZDHHC17	13 interactors: ABCB8 ABCF3 AIFM1 ARF1 BOK COL9A2 DCTPP1 GRB10 H1F0 HSPA8 MPP3 NFU1 WDR18
Entrez ID		2887	84273
HPRD ID		03312	12823
Ensembl ID		ENSG00000106070
Uniprot IDs		Q13322	Q8NC60
PDB IDs		1NRV 3HK0
Enriched GO Terms of Interacting Partners?		Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Peptidyl-tyrosine Phosphorylation Protein Autophosphorylation Cell Surface Receptor Signaling Pathway Positive Regulation Of Signal Transduction Protein Phosphorylation Regulation Of MAPK Cascade Regulation Of Cell Motility Positive Regulation Of Intracellular Signal Transduction Regulation Of Signal Transduction Regulation Of Locomotion Regulation Of Cellular Component Movement Phosphorylation Cellular Response To Organic Substance Intracellular Signal Transduction Cellular Response To Hormone Stimulus Epidermal Growth Factor Receptor Signaling Pathway Positive Regulation Of MAPK Cascade Positive Regulation Of Cell Migration ERBB Signaling Pathway Positive Regulation Of Cell Motility Peptidyl-amino Acid Modification Cellular Response To Organonitrogen Compound Positive Regulation Of Cellular Component Movement Signal Transduction Positive Regulation Of Locomotion Regulation Of Signaling Regulation Of Kinase Activity Regulation Of Intracellular Signal Transduction Positive Regulation Of Phosphorylation Regulation Of Phosphorylation Response To Organic Substance Signaling Regulation Of Protein Metabolic Process Cellular Response To Peptide Hormone Stimulus Neurotrophin TRK Receptor Signaling Pathway Cell Communication Cellular Response To Peptide Neurotrophin Signaling Pathway Regulation Of Protein Kinase Activity Response To Hormone Regulation Of Cell Migration Fibroblast Growth Factor Receptor Signaling Pathway Insulin-like Growth Factor Receptor Signaling Pathway Regulation Of Phosphorus Metabolic Process Cellular Protein Modification Process Positive Regulation Of Protein Metabolic Process Positive Regulation Of Kinase Activity Fc Receptor Signaling Pathway	Apoptotic DNA Fragmentation Regulation Of Execution Phase Of Apoptosis Apoptotic Nuclear Changes Neuron Apoptotic Process Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Negative Regulation Of Fibril Organization Neuron Death Execution Phase Of Apoptosis Post-Golgi Vesicle-mediated Transport Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process DNA Catabolic Process, Endonucleolytic Activation Of Cysteine-type Endopeptidase Activity Zymogen Activation Regulation Of Fibril Organization Aromatic Compound Catabolic Process Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of Cysteine-type Endopeptidase Activity Positive Regulation Of Endopeptidase Activity DNA Catabolic Process Clathrin Coat Disassembly Positive Regulation Of Peptidase Activity Regulation Of Apoptotic DNA Fragmentation
Tagcloud ?		becomes carries cytokine driven effector emerging exert fashion fos grbir homology hybrid insights interacting looked member nonreceptor obscure phosphorylated pleckstrin profoundly ptks subfamily subset suppresses syk tec tips turned
Tagcloud (Difference) ?		becomes carries cytokine driven effector emerging exert fashion fos grbir homology hybrid insights interacting looked member nonreceptor obscure phosphorylated pleckstrin profoundly ptks subfamily subset suppresses syk tec tips turned
Tagcloud (Intersection) ?