GRB10 and MAP3K14

  • Number of citations of the paper that reports this interaction (PMID 12853971)
  • 13
  • Data Source:
  • HPRD (in vivo)

GRB10

MAP3K14

Gene Name growth factor receptor-bound protein 10 mitogen-activated protein kinase kinase kinase 14
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Acute lymphoblastic leukemia (childhood) ( 23512250)
  • Bone mineral density ( 22504420)
  • Fasting glucose-related traits (interaction with BMI) ( 22581228)
  • Systemic sclerosis ( 21779181)
Protein-Protein Interactions 30 interactors: ABL1 AKT1 APP BCR DOK1 EGFR ELK1 EPHB1 FYN GHR GIGYF1 GIGYF2 IGF1R INSR IRS1 JAK2 KDR KIT MAP2K1 MAP3K14 MAPK1 MEGF10 NEDD4 NOA1 PDGFRB RAF1 RET RQCD1 SRC ZDHHC17 39 interactors: ALPL BIRC3 BRCA1 CASP8 CDC37 CHUK EDAR EEF1A1 EGFR FBL GRB10 GRB14 GRB7 HSP90AA1 HSP90AB1 IKBKAP IKBKB IKBKG MAP2K4 MAP3K7 MAP3K8 MAPK3 NFKB2 NFKBIA PEBP1 PELI3 RIPK1 RPL30 RPL4 RPL5 RPL6 RPS11 RPS13 TRAF1 TRAF2 TRAF3 TRAF5 TRAF6 ZFP91
Entrez ID 2887 9020
HPRD ID 03312 05230
Ensembl ID ENSG00000106070
Uniprot IDs Q13322 Q99558
PDB IDs 1NRV 3HK0 4DN5 4G3D 4IDT 4IDV
Enriched GO Terms of Interacting Partners?
Tagcloud ?
becomes  carries  cytokine  driven  effector  emerging  exert  fashion  fos  grbir  homology  hybrid  insights  interacting  looked  member  nonreceptor  obscure  phosphorylated  pleckstrin  profoundly  ptks  subfamily  subset  suppresses  syk  tec  tips  turned 
alternative  bcr  birc3  called  classical  conferred  dependence  driven  exclusive  hematological  ibrutinib  insensitive  insensitivity  insights  kappab  lymphomas  malignancy  mantle  mcl  mutually  nf  nik  profiling  refractory  sequencing  sotrastaurin  stratification  traf2  transcriptome 
Tagcloud (Difference) ?
becomes  carries  cytokine  effector  emerging  exert  fashion  fos  grbir  homology  hybrid  interacting  looked  member  nonreceptor  obscure  phosphorylated  pleckstrin  profoundly  ptks  subfamily  subset  suppresses  syk  tec  tips  turned 
alternative  bcr  birc3  called  classical  conferred  dependence  exclusive  hematological  ibrutinib  insensitive  insensitivity  kappab  lymphomas  malignancy  mantle  mcl  mutually  nf  nik  profiling  refractory  sequencing  sotrastaurin  stratification  traf2  transcriptome 
Tagcloud (Intersection) ?
driven  insights