ALK and NPM1

  • Number of citations of the paper that reports this interaction (PMID 11888936)
  • 27
  • Data Source:
  • HPRD (in vitro, in vivo)

ALK

NPM1

Gene Name anaplastic lymphoma receptor tyrosine kinase nucleophosmin (nucleolar phosphoprotein B23, numatrin)
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 13 interactors: IKBKG IRS1 JAK3 MDK NPM1 PIK3R1 PLCG1 PTN PTPRZ1 SHC1 SHC3 TNFRSF8 ZC3HC1 53 interactors: ABCC1 ACY1 ALK APP ARF1 CDK1 CDK2 CDKN1A CDT1 COX8A CSNK2A1 EIF2AK2 EIF3E ELF4 EP300 ERG GADD45A GNAI2 GRB2 GZMM HAND2 HIST1H3A HIST1H4A HIST2H2AC HIST2H2BE HIST3H3 HMGA1 HMGA2 HOXA7 IRF1 IRS1 MDM2 NCL NOP2 NPM2 PADI4 PARP1 PLCG1 PLCG2 PLK1 PSMC4 RELA RPGR SENP3 SHC1 SREK1 TCERG1 TFAP2A TP53 UQCRH USP36 XPO1 YY1
Entrez ID 238 4869
HPRD ID 00104 01246
Ensembl ID ENSG00000171094 ENSG00000181163
Uniprot IDs B6D4Y2 Q9UM73 P06748
PDB IDs 2KUP 2KUQ 2XB7 2XBA 2XP2 2YFX 2YHV 2YJR 2YJS 2YS5 2YT2 3AOX 3L9P 3LCS 3LCT 4ANL 4ANQ 4ANS 4DCE 4FNW 4FNX 4FNY 4FNZ 4FOB 4FOC 4FOD 4JOA 2LLH 2P1B 2VXD
Enriched GO Terms of Interacting Partners?
Tagcloud ?
2d  accelerate  alkaline  chi2  depressed  dihydroxyvitamin  disuse  forces  fractures  hydroxyvitamin  hyperparathyroidism  immobilization  inclined  oh  osteopenia  osteoporotic  parathyroid  pg  phosphorus  po4  pth  regionally  resorption  sci  serum  skeleton  subgroup  subjects  twelve 
aggressive  aml  amplicon  consecutive  counterparts  covering  de  expands  flt3  frequent  heterogeneous  hotspots  illumina  mds  mutated  myeloid  neoplasms  next  novo  panel  prevalent  profile  profiling  ptpn11  similarly  summary  syndromes  tp53  truseq 
Tagcloud (Difference) ?
2d  accelerate  alkaline  chi2  depressed  dihydroxyvitamin  disuse  forces  fractures  hydroxyvitamin  hyperparathyroidism  immobilization  inclined  oh  osteopenia  osteoporotic  parathyroid  pg  phosphorus  po4  pth  regionally  resorption  sci  serum  skeleton  subgroup  subjects  twelve 
aggressive  aml  amplicon  consecutive  counterparts  covering  de  expands  flt3  frequent  heterogeneous  hotspots  illumina  mds  mutated  myeloid  neoplasms  next  novo  panel  prevalent  profile  profiling  ptpn11  similarly  summary  syndromes  tp53  truseq 
Tagcloud (Intersection) ?