ALK and IRS1

  • Number of citations of the paper that reports this interaction (PMID 9174053)
  • 67
  • Data Source:
  • HPRD (in vivo)

ALK

IRS1

Gene Name anaplastic lymphoma receptor tyrosine kinase insulin receptor substrate 1
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 13 interactors: IKBKG IRS1 JAK3 MDK NPM1 PIK3R1 PLCG1 PTN PTPRZ1 SHC1 SHC3 TNFRSF8 ZC3HC1 73 interactors: AKT1 ALK AP3S1 APP ATP2A1 ATP2A2 ATP2A3 BCL2L1 BCR CAV1 CDH1 CHUK CRK CSNK2A1 CSNK2B EGFR ERBB2 FBXO25 FBXW8 FER FES FYN GHR GRB10 GRB14 GRB2 IGF1R IKBKB IL4R INSR JAK1 JAK2 JAK3 MAPK1 MAPK8 MAPK9 MTOR NCK2 NEDD4 NPM1 NTRK1 PDPK1 PHIP PIK3R1 PIK3R2 PIK3R3 PLCG2 PRKCD PRKCG PRKCQ PRKCZ PTK2 PTPN1 PTPN11 PTPRC PTPRF PTPRU RAD51 ROCK1 RPS6KB1 RPTOR SH2B1 SHC1 SIK2 SOCS1 SOCS3 TUB TYK2 UBTF YWHAB YWHAE YWHAG YWHAZ
Entrez ID 238 3667
HPRD ID 00104 00943
Ensembl ID ENSG00000171094 ENSG00000169047
Uniprot IDs B6D4Y2 Q9UM73 P35568
PDB IDs 2KUP 2KUQ 2XB7 2XBA 2XP2 2YFX 2YHV 2YJR 2YJS 2YS5 2YT2 3AOX 3L9P 3LCS 3LCT 4ANL 4ANQ 4ANS 4DCE 4FNW 4FNX 4FNY 4FNZ 4FOB 4FOC 4FOD 4JOA 1IRS 1K3A 1QQG 2Z8C
Enriched GO Terms of Interacting Partners?
Tagcloud ?
2d  accelerate  alkaline  chi2  depressed  dihydroxyvitamin  disuse  forces  fractures  hydroxyvitamin  hyperparathyroidism  immobilization  inclined  oh  osteopenia  osteoporotic  parathyroid  pg  phosphorus  po4  pth  regionally  resorption  sci  serum  skeleton  subgroup  subjects  twelve 
action  adipocytes  biochem  biophys  coimmunoprecipitation  coincided  commun  docking  evidenced  extent  gh  initiating  insulin  involvement  kda  kinase  phosphatidylinositol  phosphorylated  pi  postreceptor  res  ridderstrale  seems  substrate  thereby  tornqvist  tyrosine  wortmannin 
Tagcloud (Difference) ?
2d  accelerate  alkaline  chi2  depressed  dihydroxyvitamin  disuse  forces  fractures  hydroxyvitamin  hyperparathyroidism  immobilization  inclined  oh  osteopenia  osteoporotic  parathyroid  pg  phosphorus  po4  pth  regionally  resorption  sci  serum  skeleton  subgroup  subjects  twelve 
action  adipocytes  biochem  biophys  coimmunoprecipitation  coincided  commun  docking  evidenced  extent  gh  initiating  insulin  involvement  kda  kinase  phosphatidylinositol  phosphorylated  pi  postreceptor  res  ridderstrale  seems  substrate  thereby  tornqvist  tyrosine  wortmannin 
Tagcloud (Intersection) ?