ATG4A and CDKL3

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		ATG4A	CDKL3
Gene Name		autophagy related 4A, cysteine peptidase	cyclin-dependent kinase-like 3
Image
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol	Nucleus Cytoplasm
	Molecular Function	Cysteine-type Endopeptidase Activity Cysteine-type Peptidase Activity	Protein Kinase Activity Cyclin-dependent Protein Serine/threonine Kinase Activity ATP Binding
	Biological Process	Autophagic Vacuole Assembly Mitochondrion Degradation C-terminal Protein Lipidation Proteolysis Protein Targeting To Membrane Cellular Response To Nitrogen Starvation Protein Processing Nucleophagy Protein Delipidation	Cellular Protein Modification Process Protein Phosphorylation Negative Regulation Of Axon Extension Positive Regulation Of Dendrite Morphogenesis Regulation Of Cell Cycle Dendrite Extension
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: ATG101 CDKL3 GABARAPL1 GABARAPL2 MAP1LC3B	17 interactors: APP ATG4A CCDC155 FXR2 GGA1 GOLGA2 KRTAP10-9 LZTS2 MDFI MTUS2 PIH1D3 SNRNP70 SRPK1 TRIM27 TTF2 ZBTB14 ZBTB8A
Entrez ID		115201	51265
HPRD ID		06455	09766
Ensembl ID		ENSG00000101844	ENSG00000006837
Uniprot IDs		F5H3G3 Q8WYN0	B4DX41 E7ET86 Q8IVW4
PDB IDs		2FUY 2P82	3ZDU
Enriched GO Terms of Interacting Partners?		Autophagic Vacuole Assembly Macroautophagy Vacuole Organization Cellular Response To Starvation Nucleophagy Autophagy Mitochondrion Degradation Cellular Response To Nutrient Levels Response To Starvation Cellular Response To Extracellular Stimulus Organelle Disassembly Response To Nutrient Levels Response To Extracellular Stimulus Organelle Assembly Membrane Fusion Cellular Response To Nitrogen Starvation Mitochondrion Organization Cellular Response To Stress Catabolic Process Response To External Stimulus Cellular Component Assembly Membrane Organization Dendrite Extension Organelle Organization Response To Stress Negative Regulation Of Axon Extension Positive Regulation Of ATPase Activity Positive Regulation Of Dendrite Morphogenesis Regulation Of ATPase Activity Intra-Golgi Vesicle-mediated Transport Positive Regulation Of Dendrite Development Negative Regulation Of Axonogenesis Neuron Projection Extension Cell Communication Negative Regulation Of Proteasomal Protein Catabolic Process Cellular Metabolic Process Regulation Of Axon Extension Regulation Of Dendrite Morphogenesis See more	MRNA Processing MRNA Metabolic Process Cellular Localization RNA Processing Regulation Of Binding Chromosome Localization To Nuclear Envelope Involved In Synapsis Regulation Of MRNA Splicing, Via Spliceosome Establishment Of Localization In Cell Regulation Of Gene Expression Reproductive Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Negative Regulation Of Viral Process Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Protein Localization To Nucleus Sexual Reproduction RNA Splicing Negative Regulation Of Interleukin-2 Secretion Synaptic Growth At Neuromuscular Junction Pharynx Development Regulation Of MRNA Processing Negative Regulation Of Binding Intracellular Transport Regulation Of RNA Splicing RNA Metabolic Process Collateral Sprouting In Absence Of Injury Protein Delipidation Regulation Of RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Collateral Sprouting Axon Midline Choice Point Recognition Reproduction Spermatogenesis Male Gamete Generation Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Negative Regulation Of Calcium Ion Import Regulation Of Protein Binding Negative Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Viral Process Axon Choice Point Recognition Soft Palate Development Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Cellular Component Assembly Regulation Of Metabolic Process See more
Tagcloud ?		activates atg9a autophagy bix bix01294 deficiency detailed discovered dor elusive emerged enhances h3k9 induces inducing lc3 lc3b methyltransferase profiled promotes promoting puma rapamycin repressed screen selectively smyd2 transcriptionally typical	10a autophagic autophagosome autophagosomes bub1 catabolic csnk1a1 dapk2 endolysosomal flux functioned immortalized kinome macroautophagy maintains manipulation mcf mtorc1 nek4 pacsin1 pklr possibilities protects scyl1 shed sirnas starvation stresses wnk2
Tagcloud (Difference) ?		activates atg9a autophagy bix bix01294 deficiency detailed discovered dor elusive emerged enhances h3k9 induces inducing lc3 lc3b methyltransferase profiled promotes promoting puma rapamycin repressed screen selectively smyd2 transcriptionally typical	10a autophagic autophagosome autophagosomes bub1 catabolic csnk1a1 dapk2 endolysosomal flux functioned immortalized kinome macroautophagy maintains manipulation mcf mtorc1 nek4 pacsin1 pklr possibilities protects scyl1 shed sirnas starvation stresses wnk2
Tagcloud (Intersection) ?