ATG4A and GABARAPL2

Number of citations of the paper that reports this interaction (PMID 12473658)
15

Data Source:
HPRD (in vitro, in vivo)

		ATG4A	GABARAPL2
Gene Name		autophagy related 4A, cysteine peptidase	GABA(A) receptor-associated protein-like 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol	Golgi Membrane Pre-autophagosomal Structure Autophagic Vacuole Membrane Intracellular Cytoplasm Autophagic Vacuole Golgi Apparatus Cytosol Extrinsic Component Of Membrane Cytoplasmic Vesicle
	Molecular Function	Cysteine-type Endopeptidase Activity Cysteine-type Peptidase Activity	SNARE Binding Protein Binding Microtubule Binding Beta-tubulin Binding GABA Receptor Binding ATPase Binding
	Biological Process	Autophagic Vacuole Assembly Mitochondrion Degradation C-terminal Protein Lipidation Proteolysis Protein Targeting To Membrane Cellular Response To Nitrogen Starvation Protein Processing Nucleophagy Protein Delipidation	Autophagic Vacuole Assembly Mitochondrion Degradation Intra-Golgi Vesicle-mediated Transport Autophagy Cellular Response To Nitrogen Starvation Protein Transport Positive Regulation Of ATPase Activity Nucleophagy Membrane Fusion Negative Regulation Of Proteasomal Protein Catabolic Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: ATG101 CDKL3 GABARAPL1 GABARAPL2 MAP1LC3B	50 interactors: AAMP AGTRAP AHNAK2 APP ARFGAP1 ATG13 ATG3 ATG4A ATG4B ATG4D ATG7 BCL2L13 CALCOCO1 CALCOCO2 CCDC155 CLN8 EGFR FUNDC1 GIMAP6 GOSR1 KBTBD7 KIAA1958 KLHL5 KRTAP10-7 KRTAP10-9 LRSAM1 MAP1LC3B MLX NBR1 NSF PTPRA RAP1A RAP2A RCN2 RPS2 SGTA SIK2 SQSTM1 TBC1D25 TBC1D5 TBC1D9 TBC1D9B TNIP1 TP53INP2 TSR2 UBA5 ULK1 ULK2 VDR YWHAZ
Entrez ID		115201	11345
HPRD ID		06455	16246
Ensembl ID		ENSG00000101844	ENSG00000034713
Uniprot IDs		F5H3G3 Q8WYN0	P60520
PDB IDs		2FUY 2P82
Enriched GO Terms of Interacting Partners?		Autophagic Vacuole Assembly Macroautophagy Vacuole Organization Cellular Response To Starvation Nucleophagy Autophagy Mitochondrion Degradation Cellular Response To Nutrient Levels Response To Starvation Cellular Response To Extracellular Stimulus Organelle Disassembly Response To Nutrient Levels Response To Extracellular Stimulus Organelle Assembly Membrane Fusion Cellular Response To Nitrogen Starvation Mitochondrion Organization Cellular Response To Stress Catabolic Process Response To External Stimulus Cellular Component Assembly Membrane Organization Dendrite Extension Organelle Organization Response To Stress Negative Regulation Of Axon Extension Positive Regulation Of ATPase Activity Positive Regulation Of Dendrite Morphogenesis Regulation Of ATPase Activity Intra-Golgi Vesicle-mediated Transport Positive Regulation Of Dendrite Development Negative Regulation Of Axonogenesis Neuron Projection Extension Cell Communication Negative Regulation Of Proteasomal Protein Catabolic Process Cellular Metabolic Process Regulation Of Axon Extension Regulation Of Dendrite Morphogenesis	Autophagy Macroautophagy Response To Starvation Cellular Response To Nutrient Levels Cellular Response To Starvation Autophagic Vacuole Assembly Cellular Response To Extracellular Stimulus Response To Nutrient Levels Response To Extracellular Stimulus Vacuole Organization Mitochondrion Degradation Organelle Disassembly Nucleophagy Membrane Organization Positive Regulation Of Autophagy Response To Stress Cellular Response To Nitrogen Starvation Catabolic Process Regulation Of Autophagy Response To External Stimulus Protein Localization Establishment Of Protein Localization Protein Delipidation Mitochondrion Organization Cellular Response To Stress Positive Regulation Of Metabolic Process Organelle Assembly C-terminal Protein Lipidation Establishment Of Protein Localization To Membrane Protein Localization To Membrane Protein Transport Positive Regulation Of Cellular Metabolic Process Intracellular Transport Cellular Localization Cell Communication Positive Regulation Of Macroautophagy Cellular Component Assembly Response To Stimulus Establishment Of Localization In Cell Cellular Response To Stimulus Protein Targeting To Membrane Regulation Of Signaling Regulation Of Signal Transduction Organelle Organization Cellular Metabolic Process Protein Lipidation Lipoprotein Biosynthetic Process Negative Regulation Of Collateral Sprouting Positive Regulation Of Catalytic Activity Positive Regulation Of Hydrolase Activity
Tagcloud ?		activates atg9a autophagy bix bix01294 deficiency detailed discovered dor elusive emerged enhances h3k9 induces inducing lc3 lc3b methyltransferase profiled promotes promoting puma rapamycin repressed screen selectively smyd2 transcriptionally typical
Tagcloud (Difference) ?		activates atg9a autophagy bix bix01294 deficiency detailed discovered dor elusive emerged enhances h3k9 induces inducing lc3 lc3b methyltransferase profiled promotes promoting puma rapamycin repressed screen selectively smyd2 transcriptionally typical
Tagcloud (Intersection) ?