CDC42EP4 and FAM9B

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		CDC42EP4	FAM9B
Description		CDC42 effector protein 4	family with sequence similarity 9 member B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Plasma Membrane Adherens Junction Endomembrane System Actin Cytoskeleton Microtubule Cytoskeleton Membrane Phagocytic Vesicle	Synaptonemal Complex Nucleus Nucleoplasm Chromosome Cytoplasm
	Molecular Function	RNA Binding Protein Binding Small GTPase Binding	Protein Binding
	Biological Process	Rho Protein Signal Transduction Regulation Of Cell Shape Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Pseudopodium Assembly Cellular Response To Type II Interferon	Spermatid Development Meiotic Cell Cycle
Pathways		CDC42 GTPase cycle RAC1 GTPase cycle RAC2 GTPase cycle RHOQ GTPase cycle
Drugs
Diseases
GWAS			Age at voice drop ( 27182965) Androgen levels ( 22936694) Creatinine levels ( 29403010) Glomerular filtration rate ( 29403010) Heel bone mineral density ( 28869591 30598549) Hematocrit ( 29403010) Hemoglobin ( 29403010) Male-pattern baldness ( 27182965 29146897) Metabolite levels ( 23823483)
Interacting Genes		8 interacting genes: APP CDC42 FAM9B LNX1 RHOQ SRPK2 TGFBR1 WDR6	140 interacting genes: ABT1 ACP6 ANKRD36B AP1M1 ASB6 ATF7 AURKAIP1 BAG6 BAIAP2L2 BARD1 BCL2A1 BET1 BLOC1S2 BRME1 BYSL C8orf33 CADPS CCDC106 CCDC116 CCDC198 CCDC70 CDC23 CDC37 CDC42EP4 CDCA7L CDSN CENPL CEP57L1 CEP95 CHRAC1 CLCN1 CMTM6 COL20A1 CSDE1 CWF19L2 DAPK2 DAXX DENND2D DGUOK DNAJC15 DNAJC4 EBNA1BP2 ECH1 EIF3G ELOA FAM161A FAM9A FASTKD3 FCHSD2 FERD3L FNDC11 GFOD1 GOPC GPX1 GRAMD4 GSTK1 HAPSTR1 HNRNPLL IBSP ISCU JAZF1 LBX1 LIN7A LINC02363 LMNA LNX1 LYRM2 MAB21L3 MFAP1 MOB1A MORF4L1 MORF4L2 MRPL10 MRPL28 MRPL9 MRRF MYG1 MYO15B NDE1 NDUFB10 NEBL NOL4 NOTO PAGE1 PAGE3 PHYH PIN4 POLL PPARA PPP1R18 PRPF3 PSMD14 PTRH1 RAB17 RAD51B RBM17 RBM23 RMND1 RNF8 RPL9 RSL24D1 RUBCN RUSC1 SDCBP SDCBP2 SERPINE2 SFN SLC16A3 SLPI SMARCB1 SMN1 SMN2 SNAP29 SNAP47 SNX20 SRRM4 STK3 SUCLA2 SURF6 SYT17 TBC1D25 TBRG4 TCEA2 TCEANC TGFBI TOM1L2 TRMT61B TSG101 TUFM TXN2 UBE2E2 URB1-AS1 WT1 YARS2 ZCCHC10 ZGPAT ZNF41 ZNF410 ZNF567 ZNF614
Entrez ID		23580	171483
HPRD ID		08383	15955
Ensembl ID		ENSG00000179604	ENSG00000177138
Uniprot IDs		B2R6D8 Q9H3Q1	Q8IZU0
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Filopodium Assembly GBD Domain Binding Regulation Of Filopodium Assembly Positive Regulation Of Plasma Membrane Bounded Cell Projection Assembly Filopodium Assembly Positive Regulation Of Supramolecular Fiber Organization Membrane Raft Regulation Of Plasma Membrane Bounded Cell Projection Organization Neuron Projection Organization Postsynapse Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Regulation Of Cell Projection Assembly Peptidyl-serine Phosphorylation Regulation Of Cell Projection Organization Positive Regulation Of Stress Fiber Assembly Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Positive Regulation Of Actin Filament Bundle Assembly Positive Regulation Of Cell Cycle Positive Regulation Of Neuron Apoptotic Process Regulation Of Actin Cytoskeleton Organization Acetylcholine Receptor Activator Activity PTB Domain Binding Cellular Developmental Process Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Intracellular Signal Transduction System Development Intracellular Signaling Cassette Regulation Of Cell Population Proliferation Endosome To Plasma Membrane Transport Vesicle Regulation Of Supramolecular Fiber Organization Positive Regulation Of Endothelin Production Growth Cone Filopodium Endocytosis Lipoprotein Particle Cell Junction Organization Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Regulation Of Cell Cycle Endothelin Receptor Signaling Pathway Involved In Heart Process Regulation Of Actin Filament-based Process Regulation Of Stress Fiber Assembly Establishment Of Cell Polarity	Protein Binding Mitochondrial Matrix RNA Binding
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