CDC42EP4 and FAM9B

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		CDC42EP4	FAM9B
Gene Name		CDC42 effector protein (Rho GTPase binding) 4	family with sequence similarity 9, member B
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Plasma Membrane Endomembrane System Actin Cytoskeleton Microtubule Cytoskeleton	Nucleoplasm
	Molecular Function	Rho GTPase Activator Activity GTP-Rho Binding Poly(A) RNA Binding
	Biological Process	Rho Protein Signal Transduction Regulation Of Cell Shape Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Pseudopodium Assembly Positive Regulation Of Rho GTPase Activity
Pathways
Drugs
Diseases
GWAS			Androgen levels ( 22936694)
Protein-Protein Interactions		8 interactors: APP CDC42 FAM9B LNX1 RHOQ SRPK2 TGFBR1 WDR6	118 interactors: ABT1 ACP6 ANKRD36B AP1M1 ASB6 ATF7 AURKAIP1 BAG6 BARD1 BCL2A1 BET1 BLOC1S2 BYSL C12orf10 C14orf105 C16orf72 C19orf57 C20orf195 C8orf33 CADPS CCDC106 CCDC116 CCDC70 CDC23 CDC42EP4 CDCA7L CENPL CEP57L1 CEP95 CHRAC1 CLCN1 CMTM6 COL20A1 CSDE1 CWF19L2 DAPK2 DAXX DENND2D DNAJC15 DNAJC4 EBNA1BP2 ECH1 EIF3G FAM161A FASTKD3 FCHSD2 FERD3L GFOD1 GOPC GPX1 GSTK1 ISCU LIN7A LNX1 LOC728175 LYRM2 MAB21L3 MFAP1 MOB1A MORF4L1 MORF4L2 MRPL10 MRPL28 MRPL9 MYO15B NDE1 NDUFB10 NEBL NOL4 PAGE1 PAGE3 PHYH PIN4 POLL PPP1R18 PRPF3 PSMD14 PTRH1 RAB17 RAD51B RBM17 RBM23 RMND1 RPL9 RSL24D1 RUSC1 SDCBP SDCBP2 SERPINE2 SFN SLC16A3 SLPI SMN2 SNAP29 SNAP47 SNX20 STK3 SUCLA2 SYT17 TBRG4 TCEA2 TCEANC TCEB3 TGFBI TRMT61B TSG101 TUFM TXN2 UBE2E2 URB1-AS1 XRCC4 YARS2 ZCCHC10 ZGPAT ZNF41 ZNF410 ZNF567 ZNF614
Entrez ID		23580	171483
HPRD ID		08383	15955
Ensembl ID		ENSG00000179604	ENSG00000177138
Uniprot IDs		B2R6D8 B3KUS7 Q9H3Q1	Q8IZU0 Q8N7Z8
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Filopodium Assembly Regulation Of Cell Cycle Regulation Of Cell Projection Assembly Regulation Of Protein Binding Positive Regulation Of Gene Expression Positive Regulation Of Filopodium Assembly Regulation Of Binding Positive Regulation Of Cell Projection Organization Positive Regulation Of Cell Cycle Positive Regulation Of Cellular Component Biogenesis Angiogenesis Positive Regulation Of Neuron Apoptotic Process Blood Vessel Morphogenesis Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Positive Regulation Of Neuron Death Neuron Fate Commitment Regulation Of ERBB Signaling Pathway Regulation Of Cell Morphogenesis Regulation Of Cell Projection Organization Nuclear Speck Organization Regulation Of Synapse Structure Or Activity Blood Vessel Development Vasculature Development Regulation Of Cell Proliferation Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Wound Healing Positive Regulation Of Cell Death Synaptic Growth At Neuromuscular Junction Positive Regulation Of Hair Follicle Cell Proliferation Positive Regulation Of Cellular Biosynthetic Process Microtubule-based Transport Cytoskeleton-dependent Intracellular Transport Regulation Of Establishment Of Protein Localization Cell Cycle Arrest Response To Wounding Submandibular Salivary Gland Formation Collateral Sprouting In Absence Of Injury Actin Filament Branching Cell Morphogenesis Involved In Differentiation Positive Regulation Of Intracellular Protein Transport Positive Regulation Of Transport Regulation Of Protein Kinase Activity Positive Regulation Of Metabolic Process Intracellular Signal Transduction Regulation Of Hair Follicle Cell Proliferation Positive Regulation Of Synapse Structural Plasticity Regulation Of Protein Localization Regulation Of Kinase Activity	Mitochondrial Translation Organelle Organization Translational Elongation Vesicle Organization Gene Expression Mitochondrion Organization Synaptic Vesicle Priming Mitochondrial Translational Elongation Translation Establishment Of Vesicle Localization Vesicle Localization Ribonucleoprotein Complex Biogenesis Establishment Of Organelle Localization Cellular Component Assembly Cellular Metabolic Process Synaptic Vesicle Transport Mitochondrial Translational Initiation Mitochondrial Translational Termination Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Extracellular Vesicular Exosome Assembly Cellular Macromolecular Complex Assembly Organelle Localization Translational Termination RNA Metabolic Process Translational Initiation Cellular Response To Stress Apoptotic Signaling Pathway Cellular Response To DNA Damage Stimulus Membrane Organization Protein Polyubiquitination Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Synaptic Vesicle Fusion To Presynaptic Membrane Cellular Process Cellular Protein Complex Disassembly Intrinsic Apoptotic Signaling Pathway Ribosome Biogenesis Neurotransmitter Secretion Macromolecule Biosynthetic Process Vesicle Fusion Pigmentation Protein Complex Disassembly Synaptic Vesicle Exocytosis Viral Process Cellular Pigmentation
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