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CDC42EP4 and WDR6
Number of citations of the paper that reports this interaction (PMID
16189514
)
699
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
CDC42EP4
WDR6
Gene Name
CDC42 effector protein (Rho GTPase binding) 4
WD repeat domain 6
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytoplasm
Plasma Membrane
Endomembrane System
Actin Cytoskeleton
Microtubule Cytoskeleton
Cytoplasm
Plasma Membrane
COP9 Signalosome
Molecular Function
Rho GTPase Activator Activity
GTP-Rho Binding
Poly(A) RNA Binding
Protein Binding
Poly(A) RNA Binding
Biological Process
Rho Protein Signal Transduction
Regulation Of Cell Shape
Positive Regulation Of Actin Filament Polymerization
Positive Regulation Of Pseudopodium Assembly
Positive Regulation Of Rho GTPase Activity
Cell Cycle Arrest
Negative Regulation Of Cell Proliferation
Negative Regulation Of Autophagy
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions
8 interactors:
APP
CDC42
FAM9B
LNX1
RHOQ
SRPK2
TGFBR1
WDR6
4 interactors:
BRCA1
CDC42EP4
G2E3
PTPN3
Entrez ID
23580
11180
HPRD ID
08383
06912
Ensembl ID
ENSG00000179604
ENSG00000178252
Uniprot IDs
B2R6D8
B3KUS7
Q9H3Q1
B3KRR8
E9PDU5
Q9H9M3
Q9NNW5
PDB IDs
Enriched GO Terms of Interacting Partners
?
Regulation Of Filopodium Assembly
Regulation Of Cell Cycle
Regulation Of Cell Projection Assembly
Regulation Of Protein Binding
Positive Regulation Of Gene Expression
Positive Regulation Of Filopodium Assembly
Regulation Of Binding
Positive Regulation Of Cell Projection Organization
Positive Regulation Of Cell Cycle
Positive Regulation Of Cellular Component Biogenesis
Angiogenesis
Positive Regulation Of Neuron Apoptotic Process
Blood Vessel Morphogenesis
Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Positive Regulation Of Neuron Death
Neuron Fate Commitment
Regulation Of ERBB Signaling Pathway
Regulation Of Cell Morphogenesis
Regulation Of Cell Projection Organization
Nuclear Speck Organization
Regulation Of Synapse Structure Or Activity
Blood Vessel Development
Vasculature Development
Regulation Of Cell Proliferation
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Apoptotic Process
Positive Regulation Of Programmed Cell Death
Wound Healing
Positive Regulation Of Cell Death
Synaptic Growth At Neuromuscular Junction
Positive Regulation Of Hair Follicle Cell Proliferation
Positive Regulation Of Cellular Biosynthetic Process
Microtubule-based Transport
Cytoskeleton-dependent Intracellular Transport
Regulation Of Establishment Of Protein Localization
Cell Cycle Arrest
Response To Wounding
Submandibular Salivary Gland Formation
Collateral Sprouting In Absence Of Injury
Actin Filament Branching
Cell Morphogenesis Involved In Differentiation
Positive Regulation Of Intracellular Protein Transport
Positive Regulation Of Transport
Regulation Of Protein Kinase Activity
Positive Regulation Of Metabolic Process
Intracellular Signal Transduction
Regulation Of Hair Follicle Cell Proliferation
Positive Regulation Of Synapse Structural Plasticity
Regulation Of Protein Localization
Regulation Of Kinase Activity
Positive Regulation Of Histone H4-K20 Methylation
Positive Regulation Of Histone H4-K16 Acetylation
Protein Polyubiquitination
Positive Regulation Of Histone H3-K9 Acetylation
Positive Regulation Of Histone H4 Acetylation
Negative Regulation Of Histone H3-K4 Methylation
Liver Regeneration
Negative Regulation Of Apoptotic Signaling Pathway
Regulation Of Membrane Depolarization During Action Potential
Cellular Response To Indole-3-methanol
Negative Regulation Of Centriole Replication
Negative Regulation Of Membrane Protein Ectodomain Proteolysis
Dosage Compensation By Inactivation Of X Chromosome
Protein K6-linked Ubiquitination
Negative Regulation Of Histone H3-K9 Methylation
Positive Regulation Of Histone H3-K9 Methylation
Dosage Compensation
Regulation Of Histone H3-K9 Acetylation
Positive Regulation Of Organelle Organization
Regulation Of Centriole Replication
Positive Regulation Of Histone H3-K4 Methylation
Regulation Of Histone H4 Acetylation
Negative Regulation Of Fatty Acid Biosynthetic Process
Positive Regulation Of Pseudopodium Assembly
DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator
Negative Regulation Of Cell Cycle
DNA Damage Response, Signal Transduction Resulting In Transcription
Negative Regulation Of Histone Methylation
Regulation Of Cytoskeleton Organization
Negative Regulation Of Centrosome Duplication
Regulation Of DNA Methylation
Negative Regulation Of Histone Acetylation
Positive Regulation Of Histone Acetylation
Negative Regulation Of Peptidyl-lysine Acetylation
Regulation Of Histone H3-K4 Methylation
Protein Ubiquitination
Negative Regulation Of Protein Acetylation
Positive Regulation Of Peptidyl-lysine Acetylation
Postreplication Repair
Positive Regulation Of Protein Acetylation
Protein Modification By Small Protein Conjugation
Regulation Of Transcription From RNA Polymerase III Promoter
Negative Regulation Of Fatty Acid Metabolic Process
Regulation Of Gene Expression By Genetic Imprinting
Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Regulation Of Sodium Ion Transmembrane Transporter Activity
Genetic Imprinting
Regulation Of Fatty Acid Biosynthetic Process
Positive Regulation Vascular Endothelial Growth Factor Production
G2 DNA Damage Checkpoint
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