CDC42EP4

Description		CDC42 effector protein 4
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Plasma Membrane Adherens Junction Endomembrane System Actin Cytoskeleton Microtubule Cytoskeleton Membrane Phagocytic Vesicle
	Molecular Function	RNA Binding Protein Binding Small GTPase Binding
	Biological Process	Rho Protein Signal Transduction Regulation Of Cell Shape Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Pseudopodium Assembly Cellular Response To Type II Interferon
Pathways		CDC42 GTPase cycle RAC1 GTPase cycle RAC2 GTPase cycle RHOQ GTPase cycle
Drugs
Diseases
GWAS
Novel Interacting Genes		1 novel interacting genes: BRD2
Interacting Genes		8 interacting genes: APP CDC42 FAM9B LNX1 RHOQ SRPK2 TGFBR1 WDR6
Entrez ID		23580
HPRD ID		08383
Ensembl ID		ENSG00000179604
Uniprot IDs		B2R6D8 Q9H3Q1
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Filopodium Assembly GBD Domain Binding Regulation Of Filopodium Assembly Positive Regulation Of Plasma Membrane Bounded Cell Projection Assembly Filopodium Assembly Positive Regulation Of Supramolecular Fiber Organization Membrane Raft Regulation Of Plasma Membrane Bounded Cell Projection Organization Neuron Projection Organization Postsynapse Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Regulation Of Cell Projection Assembly Peptidyl-serine Phosphorylation Regulation Of Cell Projection Organization Positive Regulation Of Stress Fiber Assembly Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Positive Regulation Of Actin Filament Bundle Assembly Positive Regulation Of Cell Cycle Positive Regulation Of Neuron Apoptotic Process Regulation Of Actin Cytoskeleton Organization Acetylcholine Receptor Activator Activity PTB Domain Binding Cellular Developmental Process Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Intracellular Signal Transduction System Development Intracellular Signaling Cassette Regulation Of Cell Population Proliferation Endosome To Plasma Membrane Transport Vesicle Regulation Of Supramolecular Fiber Organization Positive Regulation Of Endothelin Production Growth Cone Filopodium Endocytosis Lipoprotein Particle Cell Junction Organization Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Regulation Of Cell Cycle Endothelin Receptor Signaling Pathway Involved In Heart Process Regulation Of Actin Filament-based Process Regulation Of Stress Fiber Assembly Establishment Of Cell Polarity
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