Wiki-Pi
Answer Survey
Home
About
Help
Advanced Search
ECT2 and C2orf42
Number of citations of the paper that reports this interaction (PMID
22990118
)
7
Data Source:
BioGRID
(two hybrid)
ECT2
C2orf42
Gene Name
epithelial cell transforming 2
chromosome 2 open reading frame 42
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Cytoplasm
Cytosol
Cell-cell Junction
Tight Junction
Midbody
Nuclear Membrane
Cleavage Furrow
Intracellular Membrane-bounded Organelle
Mitotic Spindle
Centralspindlin Complex
Nucleus
Nucleoplasm
Nuclear Membrane
Molecular Function
Signal Transducer Activity
Rho Guanyl-nucleotide Exchange Factor Activity
GTPase Activator Activity
Protein Binding
Rho GTPase Binding
Protein Homodimerization Activity
Biological Process
Cell Morphogenesis
Cytokinesis
Small GTPase Mediated Signal Transduction
Protein Transport
Activation Of Protein Kinase Activity
Positive Regulation Of Rho GTPase Activity
Positive Regulation Of Cytokinesis
Activation Of Rho GTPase Activity
Activation Of Rac GTPase Activity
Positive Regulation Of Protein Import Into Nucleus
Positive Regulation Of Apoptotic Process
Positive Regulation Of Cdc42 GTPase Activity
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Positive Regulation Of Neuron Differentiation
Regulation Of Protein Kinase Activity
Neurotrophin TRK Receptor Signaling Pathway
Regulation Of Small GTPase Mediated Signal Transduction
Protein Homooligomerization
Regulation Of Attachment Of Spindle Microtubules To Kinetochore
Cellular Response To Hydrogen Peroxide
Tight Junction Assembly
Cellular Response To Calcium Ion
Cellular Response To Ionizing Radiation
Apoptotic Signaling Pathway
Pathways
Rho GTPase cycle
Signaling by GPCR
GPCR downstream signaling
Signalling by NGF
Cell death signalling via NRAGE, NRIF and NADE
Signaling by Rho GTPases
NRAGE signals death through JNK
G alpha (12/13) signalling events
p75 NTR receptor-mediated signalling
Drugs
Diseases
GWAS
Obesity-related traits (
23251661
)
Obesity-related traits (
23251661
)
Protein-Protein Interactions
37 interactors:
ABR
C2orf42
CCDC91
CD19
CDK1
CHST10
COX2
CRIPAK
CSTB
EIF4A2
EIF5B
ERAL1
F2RL2
FANCM
GGN
ILVBL
KLHL20
MBD1
MT2A
NOMO1
NPC2
OOSP2
OTUB1
PARD6A
PCOLCE
PLK1
POMP
PSMA6
RACGAP1
RHOG
RPS20
SNRNP200
SPATA22
TCEB1
THAP11
UBB
VDAC2
3 interactors:
ALAS1
ECT2
PAXIP1
Entrez ID
1894
54980
HPRD ID
11860
07927
Ensembl ID
ENSG00000114346
ENSG00000115998
Uniprot IDs
G5E9L8
Q9H8V3
Q9NWW7
PDB IDs
3L46
Enriched GO Terms of Interacting Partners
?
Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition
Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Ubiquitin-protein Transferase Activity
Positive Regulation Of Ligase Activity
Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Regulation Of Ubiquitin-protein Transferase Activity
Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Regulation Of Protein Ubiquitination
Cellular Macromolecule Catabolic Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Proteasomal Protein Catabolic Process
Positive Regulation Of Protein Ubiquitination
Positive Regulation Of Cell Cycle
Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process
Positive Regulation Of Proteolysis
Negative Regulation Of Transferase Activity
Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Cellular Protein Catabolic Process
DNA Damage Checkpoint
Modification-dependent Protein Catabolic Process
Mitotic Cell Cycle Checkpoint
Proteolysis Involved In Cellular Protein Catabolic Process
Viral Process
Cellular Protein Catabolic Process
Response To Stress
Cellular Response To DNA Damage Stimulus
Regulation Of Apoptotic Process
Protein Catabolic Process
Cellular Response To Stress
Neurotrophin TRK Receptor Signaling Pathway
Regulation Of Cell Death
Positive Regulation Of Protein Catabolic Process
Negative Regulation Of Mitotic Cell Cycle
Positive Regulation Of Cell Cycle Process
Neurotrophin Signaling Pathway
Regulation Of Cell Cycle
Regulation Of Cellular Protein Metabolic Process
Cell Cycle Checkpoint
Regulation Of Proteolysis
Regulation Of Catalytic Activity
Mitotic DNA Damage Checkpoint
Cellular Response To Hypoxia
Cellular Response To Decreased Oxygen Levels
Mitotic DNA Integrity Checkpoint
Negative Regulation Of Cell Cycle
Negative Regulation Of Protein Ubiquitination
Mitotic Cell Cycle Phase Transition
Cell Cycle
Cell Cycle Phase Transition
Response To Ionizing Radiation
Positive Regulation Of Histone H3-K36 Methylation
Chorion Development
Response To Radiation
Protoporphyrinogen IX Biosynthetic Process
Protoporphyrinogen IX Metabolic Process
Activation Of Rac GTPase Activity
Positive Regulation Of Transcription Initiation From RNA Polymerase II Promoter
Positive Regulation Of Histone H3-K4 Methylation
Positive Regulation Of DNA-templated Transcription, Initiation
Positive Regulation Of Cdc42 GTPase Activity
Positive Regulation Of Histone Acetylation
Regulation Of DNA-templated Transcription, Initiation
Regulation Of Attachment Of Spindle Microtubules To Kinetochore
Regulation Of Histone H3-K4 Methylation
Positive Regulation Of Peptidyl-lysine Acetylation
Positive Regulation Of Isotype Switching
Positive Regulation Of Protein Acetylation
Regulation Of Cdc42 GTPase Activity
Heme Biosynthetic Process
Regulation Of Cdc42 Protein Signal Transduction
Histone H3-K4 Methylation
Regulation Of Isotype Switching
Positive Regulation Of Protein Modification Process
Regulation Of Organelle Organization
Positive Regulation Of Immunoglobulin Mediated Immune Response
Porphyrin-containing Compound Biosynthetic Process
Adipose Tissue Development
Positive Regulation Of Histone Methylation
Positive Regulation Of Immunoglobulin Production
Activation Of Rho GTPase Activity
Positive Regulation Of Cytokinesis
Heme Metabolic Process
Regulation Of Histone Acetylation
Tight Junction Assembly
Response To Abiotic Stimulus
Cellular Response To Calcium Ion
Positive Regulation Of Cellular Protein Metabolic Process
Porphyrin-containing Compound Metabolic Process
Regulation Of Histone Methylation
Activation Of Ras GTPase Activity
Positive Regulation Of Rac GTPase Activity
Regulation Of Cytokinesis
Cellular Response To Ionizing Radiation
Cellular Response To Hydrogen Peroxide
Pigment Biosynthetic Process
Positive Regulation Of Protein Metabolic Process
Regulation Of DNA Recombination
Positive Regulation Of Histone Modification
Apical Junction Assembly
Tagcloud
?
broader
correlate
correlates
cytoskeleton
dbl
dbs
deregulated
encodes
exchange
family
gtpases
guanine
jun
lfc
lsc
mpk2
nh2
oncogenes
panel
possess
rho
sets
specificities
structurally
transformed
transforming
utilization
versions
weakly
Tagcloud (Difference)
?
broader
correlate
correlates
cytoskeleton
dbl
dbs
deregulated
encodes
exchange
family
gtpases
guanine
jun
lfc
lsc
mpk2
nh2
oncogenes
panel
possess
rho
sets
specificities
structurally
transformed
transforming
utilization
versions
weakly
Tagcloud (Intersection)
?