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ECT2 and ERAL1
Number of citations of the paper that reports this interaction (PubMedID
22990118
)
93
Data Source:
BioGRID
(two hybrid)
ECT2
ERAL1
Description
epithelial cell transforming 2
Era like 12S mitochondrial rRNA chaperone 1
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Centrosome
Spindle
Cytosol
Cytoskeleton
Cell-cell Junction
Bicellular Tight Junction
Cell Cortex
Nuclear Body
Midbody
Cleavage Furrow
Anchoring Junction
Mitotic Spindle
Centralspindlin Complex
Mitochondrion
Mitochondrial Inner Membrane
Mitochondrial Matrix
Cytosol
Membrane
Molecular Function
Guanyl-nucleotide Exchange Factor Activity
GTPase Activator Activity
Protein Binding
Small GTPase Binding
Protein Homodimerization Activity
Nucleotide Binding
RNA Binding
Protein Binding
GTP Binding
RRNA Binding
Ribosomal Small Subunit Binding
Biological Process
Mitotic Cytokinesis
Cell Morphogenesis
Nervous System Development
Protein Transport
Cell Differentiation
Activation Of Protein Kinase Activity
Positive Regulation Of Cytokinesis
Intracellular Signal Transduction
Positive Regulation Of Protein Import Into Nucleus
Positive Regulation Of Apoptotic Process
Positive Regulation Of Canonical NF-kappaB Signal Transduction
Positive Regulation Of GTPase Activity
Positive Regulation Of Neuron Differentiation
Regulation Of Protein Kinase Activity
Regulation Of Small GTPase Mediated Signal Transduction
Protein Homooligomerization
Cell Division
Regulation Of Attachment Of Spindle Microtubules To Kinetochore
Cellular Response To Hydrogen Peroxide
Bicellular Tight Junction Assembly
Cellular Response To Calcium Ion
Cellular Response To Ionizing Radiation
Activation Of GTPase Activity
Positive Regulation Of Mitotic Cytokinetic Process
Regulation Of Cytokinesis, Actomyosin Contractile Ring Assembly
Ribosomal Small Subunit Assembly
Ribosome Biogenesis
Pathways
NRAGE signals death through JNK
G alpha (12/13) signalling events
RHOA GTPase cycle
RHOB GTPase cycle
CDC42 GTPase cycle
RAC1 GTPase cycle
Mitochondrial translation initiation
Mitochondrial translation elongation
Mitochondrial translation elongation
Mitochondrial translation termination
Mitochondrial ribosome-associated quality control
Drugs
Diseases
GWAS
Obesity-related traits (
23251661
)
Red cell distribution width (
32888494
)
Estimated glomerular filtration rate reduction (30%) (
30955190
)
Glycated hemoglobin levels (
28898252
34059833
)
High light scatter reticulocyte count (
27863252
)
High light scatter reticulocyte percentage of red cells (
27863252
)
Immature fraction of reticulocytes (
27863252
32888494
)
Mean corpuscular hemoglobin (
28017375
)
Mean corpuscular volume (
29403010
)
Pulse pressure (
30224653
)
Red cell distribution width (
32888494
)
Interacting Genes
39 interacting genes:
ABR
C2orf42
CCDC91
CD19
CDK1
CHST10
CSTB
EIF4A2
EIF5B
ELOC
ERAL1
F2RL2
FANCM
GGN
HACL2
KLHL20
LAMTOR5
MBD1
MT-CO2
MT2A
NOMO1
NPC2
OOSP2
OTUB1
PARD6A
PCOLCE
PLK1
POMP
PSMA6
RACGAP1
RHOG
RPS20
SNRNP200
SPATA22
SRPK2
THAP11
UBB
USP7
VDAC2
48 interacting genes:
CEP44
ECT2
EXOSC8
MIR1-1
MIR106A
MIR106B
MIR107
MIR122
MIR138-1
MIR141
MIR145
MIR155
MIR15A
MIR15B
MIR16-1
MIR16-2
MIR17
MIR199A1
MIR199A2
MIR19A
MIR19B1
MIR200A
MIR200B
MIR206
MIR20A
MIR20B
MIR21
MIR214
MIR221
MIR29B2
MIR34B
MIR451A
MIR7-2
MIR7-3
MIR9-1
MIR9-2
MIR9-3
MIRLET7A1
MIRLET7A2
MIRLET7A3
MIRLET7B
MIRLET7C
MIRLET7D
MIRLET7E
MIRLET7F1
MIRLET7I
SRSF4
SSX2IP
Entrez ID
1894
26284
HPRD ID
11860
08466
Ensembl ID
ENSG00000114346
ENSG00000132591
Uniprot IDs
Q9H8V3
O75616
PDB IDs
3L46
4N40
6L30
8CSP
8CSQ
Enriched GO Terms of Interacting Partners
?
Cytosol
Positive Regulation Of Protein Monoubiquitination
Regulation Of Protein Monoubiquitination
MiRNA-mediated Post-transcriptional Gene Silencing
RISC Complex
Regulatory NcRNA-mediated Post-transcriptional Gene Silencing
Post-transcriptional Gene Silencing
Regulatory NcRNA-mediated Gene Silencing
MRNA Base-pairing Post-transcriptional Repressor Activity
Post-transcriptional Regulation Of Gene Expression
Negative Regulation Of Gene Expression
MiRNA-mediated Gene Silencing By Inhibition Of Translation
MRNA 3'-UTR Binding
Extracellular Vesicle
Negative Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of Biosynthetic Process
MiRNA-mediated Gene Silencing By MRNA Destabilization
Negative Regulation Of Macromolecule Metabolic Process
Negative Regulation Of Metabolic Process
Negative Regulation Of Translation
MRNA Destabilization
RNA Destabilization
Positive Regulation Of MRNA Catabolic Process
Positive Regulation Of MRNA Metabolic Process
Negative Regulation Of Cytokine Production
Regulation Of MRNA Stability
Regulation Of Gene Expression
Regulation Of Macromolecule Biosynthetic Process
Regulation Of RNA Stability
Regulation Of Angiogenesis
Negative Regulation Of Vascular Endothelial Growth Factor Production
Negative Regulation Of Cell Migration
Negative Regulation Of Angiogenesis
Regulation Of Vasculature Development
Negative Regulation Of Vasculature Development
Negative Regulation Of Cell Motility
Regulation Of Translation
Regulation Of Macromolecule Metabolic Process
Negative Regulation Of Locomotion
Regulation Of MRNA Metabolic Process
Negative Regulation Of Endothelial Cell Migration
Negative Regulation Of Protein Metabolic Process
Negative Regulation Of Blood Vessel Endothelial Cell Migration
Regulation Of Metabolic Process
Regulation Of Blood Vessel Endothelial Cell Migration
Regulation Of Cellular Response To Growth Factor Stimulus
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Regulation Of Endothelial Cell Migration
Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Negative Regulation Of Signal Transduction
Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Negative Regulation Of Multicellular Organismal Process
Extracellular Space
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Tagcloud (Intersection)
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