RALA and RGL4

Number of citations of the paper that reports this interaction (PubMedID 12874025)
0

Data Source:
HPRD (in vitro)

		RALA	RGL4
Description		RAS like proto-oncogene A	ral guanine nucleotide dissociation stimulator like 4
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Plasma Membrane Focal Adhesion Cell Surface Membrane Endocytic Vesicle Cytoplasmic Vesicle Membrane Cleavage Furrow Extracellular Exosome Flemming Body Synaptic Membrane Schaffer Collateral - CA1 Synapse	Plasma Membrane Cytoplasmic Vesicle
	Molecular Function	Nucleotide Binding GTPase Activity G Protein Activity Protein Binding GTP Binding Hydrolase Activity Myosin Binding GDP Binding Ubiquitin Protein Ligase Binding Edg-2 Lysophosphatidic Acid Receptor Binding ATPase Binding	Guanyl-nucleotide Exchange Factor Activity
	Biological Process	Neural Tube Closure Exocytosis Chemotaxis Signal Transduction Ras Protein Signal Transduction Regulation Of Exocytosis Receptor Internalization Regulation Of Actin Cytoskeleton Organization Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Cell Division Positive Regulation Of Filopodium Assembly Membrane Raft Localization Establishment Of Protein Localization To Mitochondrion Positive Regulation Of Mitochondrial Fission Regulation Of Postsynaptic Neurotransmitter Receptor Internalization	Small GTPase-mediated Signal Transduction Ras Protein Signal Transduction
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane p38MAPK events Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
Drugs		Guanosine-5'-Diphosphate
Diseases
GWAS
Interacting Genes		31 interacting genes: ARF1 CALM1 CNKSR2 CTCF EXOC1 EXOC2 EXOC3 EXOC4 EXOC5 EXOC6B EXOC7 EXOC8 FLNA GLS2 HSPB1 LSM2 PIH1D2 PLCD1 PLD1 PPP2R1B RAB34 RAB8B RALBP1 RALGPS1 RASSF5 REPS1 RGL2 RGL4 SMAD4 SNCA YBX3	4 interacting genes: HRAS RALA RALB RAP1A
Entrez ID		5898	266747
HPRD ID		01549	11528
Ensembl ID		ENSG00000006451	ENSG00000159496
Uniprot IDs		P11233	Q3ZCN2 Q8IZJ4
PDB IDs		1UAD 1ZC3 1ZC4 2A78 2A9K 2BOV 6P0I 6P0J 6P0K 6P0L 6P0M 6P0N 6P0O 7NQC 8FJH 8FJI
Enriched GO Terms of Interacting Partners?		Vesicle Tethering Involved In Exocytosis Exocyst Vesicle Tethering Vesicle Docking Involved In Exocytosis Membrane Fission Organelle Localization By Membrane Tethering Membrane Docking Vesicle Docking Mitotic Cytokinesis Exocytosis Cytoskeleton-dependent Cytokinesis Golgi To Plasma Membrane Transport Vesicle-mediated Transport To The Plasma Membrane Secretion By Cell Organelle Localization Post-Golgi Vesicle-mediated Transport Vesicle-mediated Transport Small GTPase Binding Secretion Membrane Organization Intracellular Protein Localization Flemming Body Establishment Of Protein Localization Localization Within Membrane Protein Transport Perinuclear Region Of Cytoplasm Golgi Vesicle Transport Regulation Of Norepinephrine Uptake Regulation Of Ral Protein Signal Transduction Transporter Regulator Activity Ras Protein Signal Transduction Cellular Localization Intracellular Signaling Cassette Regulation Of Follicle-stimulating Hormone Secretion Positive Regulation Of Follicle-stimulating Hormone Secretion Cytoplasm Plasma Membrane Regulation Of Entry Of Bacterium Into Host Cell Negative Regulation Of Macrophage Differentiation Growth Cone Membrane Regulation Of Autophagy Platelet Aggregation Positive Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Growth Cone Small GTPase-mediated Signal Transduction Positive Regulation Of Hormone Secretion Homotypic Cell-cell Adhesion Cytosol Positive Regulation Of Secretion By Cell Positive Regulation Of Secretion	GDP Binding G Protein Activity Small GTPase-mediated Signal Transduction GTPase Activity GTP Binding Ras Protein Signal Transduction Intracellular Signaling Cassette Regulation Of Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane Regulation Of Protein Localization To Synapse Positive Regulation Of Cellular Component Organization Vesicle-mediated Transport Regulation Of Receptor Localization To Synapse Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Positive Regulation Of ERBB Signaling Pathway Positive Regulation Of Cell Projection Organization Positive Regulation Of Signal Transduction Endocytosis Hydrolase Activity Nucleotide Binding Positive Regulation Of Cellular Component Biogenesis Positive Regulation Of Cell Communication Intracellular Signal Transduction Positive Regulation Of Signaling Receptor Internalization Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of ERBB Signaling Pathway ATPase Binding Import Into Cell Positive Regulation Of Immune Response Regulation Of Plasma Membrane Bounded Cell Projection Organization Regulation Of Cell Projection Organization Regulation Of Exocyst Assembly Positive Regulation Of Plasma Membrane Bounded Cell Projection Assembly Regulation Of Cellular Component Organization GTPase Complex Edg-2 Lysophosphatidic Acid Receptor Binding Regulation Of Exocyst Localization Response To Antineoplastic Agent Regulation Of Protein Localization To Cell Periphery Regulation Of Protein Localization To Membrane Receptor-mediated Endocytosis Regulation Of Immune Response Phospholipase C Activator Activity Positive Regulation Of ERK1 And ERK2 Cascade Regulation Of Exocytosis Positive Regulation Of Immune System Process Exocytosis Regulation Of Signal Transduction Regulation Of Cell Projection Assembly Regulation Of Organelle Organization
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