RALA and CNKSR2

Number of citations of the paper that reports this interaction (PubMedID 14597674)
0

Data Source:
HPRD (in vivo)

		RALA	CNKSR2
Description		RAS like proto-oncogene A	connector enhancer of kinase suppressor of Ras 2
Image
GO Annotations	Cellular Component	Mitochondrion Plasma Membrane Focal Adhesion Cell Surface Membrane Endocytic Vesicle Cytoplasmic Vesicle Membrane Cleavage Furrow Extracellular Exosome Flemming Body Synaptic Membrane Schaffer Collateral - CA1 Synapse	Cytoplasm Plasma Membrane Postsynaptic Density Membrane Neuronal Cell Body Postsynaptic Membrane Extracellular Exosome Glutamatergic Synapse Extrinsic Component Of Postsynaptic Density Membrane
	Molecular Function	Nucleotide Binding GTPase Activity G Protein Activity Protein Binding GTP Binding Hydrolase Activity Myosin Binding GDP Binding Ubiquitin Protein Ligase Binding Edg-2 Lysophosphatidic Acid Receptor Binding ATPase Binding	Protein Binding Protein Kinase Binding Identical Protein Binding
	Biological Process	Neural Tube Closure Exocytosis Chemotaxis Signal Transduction Ras Protein Signal Transduction Regulation Of Exocytosis Receptor Internalization Regulation Of Actin Cytoskeleton Organization Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Cell Division Positive Regulation Of Filopodium Assembly Membrane Raft Localization Establishment Of Protein Localization To Mitochondrion Positive Regulation Of Mitochondrial Fission Regulation Of Postsynaptic Neurotransmitter Receptor Internalization	Regulation Of Signal Transduction Intracellular Signal Transduction Postsynaptic Specialization Organization Postsynapse Organization
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane p38MAPK events Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation	MAP2K and MAPK activation Signaling by moderate kinase activity BRAF mutants Signaling by high-kinase activity BRAF mutants Signaling by BRAF and RAF1 fusions Paradoxical activation of RAF signaling by kinase inactive BRAF Signaling downstream of RAS mutants Signaling by RAF1 mutants
Drugs		Guanosine-5'-Diphosphate
Diseases
GWAS			Bipolar disorder ( 31043756) Educational attainment (years of education) ( 30038396) Schizophrenia ( 25056061) Type 2 diabetes ( 30718926)
Interacting Genes		31 interacting genes: ARF1 CALM1 CNKSR2 CTCF EXOC1 EXOC2 EXOC3 EXOC4 EXOC5 EXOC6B EXOC7 EXOC8 FLNA GLS2 HSPB1 LSM2 PIH1D2 PLCD1 PLD1 PPP2R1B RAB34 RAB8B RALBP1 RALGPS1 RASSF5 REPS1 RGL2 RGL4 SMAD4 SNCA YBX3	14 interacting genes: DLG1 DLG2 DLG3 DLG4 LRRC7 PATJ RALA RGS3 SHANK3 SMURF2 SNTA1 TJP1 TNIK YAP1
Entrez ID		5898	22866
HPRD ID		01549	06473
Ensembl ID		ENSG00000006451	ENSG00000149970
Uniprot IDs		P11233	A0A2R8Y622 A0A2R8Y700 A0A2R8Y7A1 A0A2U3TZH5 B3KPN2 Q8WXI2
PDB IDs		1UAD 1ZC3 1ZC4 2A78 2A9K 2BOV 6P0I 6P0J 6P0K 6P0L 6P0M 6P0N 6P0O 7NQC 8FJH 8FJI	2EAN 3BS5
Enriched GO Terms of Interacting Partners?		Vesicle Tethering Involved In Exocytosis Exocyst Vesicle Tethering Vesicle Docking Involved In Exocytosis Membrane Fission Organelle Localization By Membrane Tethering Membrane Docking Vesicle Docking Mitotic Cytokinesis Exocytosis Cytoskeleton-dependent Cytokinesis Golgi To Plasma Membrane Transport Vesicle-mediated Transport To The Plasma Membrane Secretion By Cell Organelle Localization Post-Golgi Vesicle-mediated Transport Vesicle-mediated Transport Small GTPase Binding Secretion Membrane Organization Intracellular Protein Localization Flemming Body Establishment Of Protein Localization Localization Within Membrane Protein Transport Perinuclear Region Of Cytoplasm Golgi Vesicle Transport Regulation Of Norepinephrine Uptake Regulation Of Ral Protein Signal Transduction Transporter Regulator Activity Ras Protein Signal Transduction Cellular Localization Intracellular Signaling Cassette Regulation Of Follicle-stimulating Hormone Secretion Positive Regulation Of Follicle-stimulating Hormone Secretion Cytoplasm Plasma Membrane Regulation Of Entry Of Bacterium Into Host Cell Negative Regulation Of Macrophage Differentiation Growth Cone Membrane Regulation Of Autophagy Platelet Aggregation Positive Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Growth Cone Small GTPase-mediated Signal Transduction Positive Regulation Of Hormone Secretion Homotypic Cell-cell Adhesion Cytosol Positive Regulation Of Secretion By Cell Positive Regulation Of Secretion	Receptor Clustering Establishment Or Maintenance Of Apical/basal Cell Polarity Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Ionotropic Glutamate Receptor Binding Protein Localization To Cell Junction Receptor Localization To Synapse Protein Localization To Synapse Establishment Or Maintenance Of Cell Polarity Regulation Of Postsynaptic Membrane Neurotransmitter Receptor Levels Neuromuscular Junction Adherens Junction Bicellular Tight Junction Localization Within Membrane Protein Localization To Membrane Cell Junction Basolateral Plasma Membrane Postsynaptic Density Kinase Binding Postsynaptic Density Membrane Cell-cell Adhesion Protein Localization To Postsynaptic Membrane Protein Localization To Postsynapse Neuron Projection Plasma Membrane AMPA Glutamate Receptor Clustering Regulation Of Cell Projection Organization Anchoring Junction Neuron Spine Synaptic Membrane Protein Kinase Binding Protein-containing Complex Localization GMP Kinase Activity Regulation Of Anatomical Structure Morphogenesis Ribonucleoside Diphosphate Metabolic Process Cell Adhesion GDP Metabolic Process Nucleoside Diphosphate Metabolic Process Regulation Of Biological Quality Cytosol Juxtaparanode Region Of Axon Neurotransmitter-gated Ion Channel Clustering Cell Junction Assembly Cellular Response To Potassium Ion Nervous System Development Cellular Localization Chemical Synaptic Transmission Dendritic Spine Morphogenesis Postsynaptic Density Organization Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane Regulation Of Plasma Membrane Bounded Cell Projection Organization
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?