BORCS8 and P2RX5

Number of citations of the paper that reports this interaction (PubMedID 27107012)
72

Data Source:
BioGRID (two hybrid)

		BORCS8	P2RX5
Description		BLOC-1 related complex subunit 8	purinergic receptor P2X 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Lysosome Lysosomal Membrane Membrane Cytoplasmic Side Of Lysosomal Membrane BORC Complex	Plasma Membrane Membrane Postsynapse
	Molecular Function	Protein Binding	Purinergic Nucleotide Receptor Activity Transmembrane Signaling Receptor Activity Extracellularly ATP-gated Monoatomic Cation Channel Activity Monoatomic Ion Channel Activity Voltage-gated Monoatomic Ion Channel Activity ATP Binding Channel Activity ATP-gated Ion Channel Activity Identical Protein Binding Ligand-gated Monoatomic Anion Channel Activity
	Biological Process	Heart Development Lysosome Localization Regulation Of Endosome Size Regulation Of Lysosome Size Organelle Transport Along Microtubule	Monoatomic Ion Transport Chloride Transport Signal Transduction Nervous System Development Response To PH Response To Zinc Ion Positive Regulation Of Calcium Ion Transport Into Cytosol Response To ATP Monoatomic Ion Transmembrane Transport Purinergic Nucleotide Receptor Signaling Pathway Osteoclast Maturation Regulation Of Skeletal Muscle Tissue Regeneration Positive Regulation Of Calcium-mediated Signaling Response To Calcium Ion Excitatory Postsynaptic Potential Calcium Ion Transmembrane Transport Monoatomic Cation Transmembrane Transport Monoatomic Anion Transmembrane Transport Positive Regulation Of Calcium Ion Import Across Plasma Membrane
Pathways			Elevation of cytosolic Ca2+ levels Platelet homeostasis
Drugs			Promethazine
Diseases
GWAS		Height ( 28552196)
Interacting Genes		6 interacting genes: AGR2 CTAG1A CTAG1B MESD P2RX5 TEX11	1 interacting genes: BORCS8
Entrez ID		729991	5026
HPRD ID		19682	09110
Ensembl ID		ENSG00000254901	ENSG00000083454
Uniprot IDs		Q96FH0	Q93086
PDB IDs
Enriched GO Terms of Interacting Partners?		TRNA Threonylcarbamoyladenosine Metabolic Process Identical Protein Binding ATP-gated Ion Channel Activity Positive Regulation Of Protein Localization To Membrane Meiotic Gene Conversion Regulation Of Cellular Localization Osteoclast Maturation Gene Conversion Ligand-gated Monoatomic Anion Channel Activity Lung Goblet Cell Differentiation Male Meiosis Chromosome Segregation Regulation Of Protein Localization To Membrane Positive Regulation Of PERK-mediated Unfolded Protein Response TRNA Metabolic Process Regulation Of Skeletal Muscle Tissue Regeneration Purinergic Nucleotide Receptor Activity Extracellularly ATP-gated Monoatomic Cation Channel Activity Positive Regulation Of IRE1-mediated Unfolded Protein Response Positive Regulation Of Skeletal Muscle Acetylcholine-gated Channel Clustering Central Element Chiasma Assembly Regulation Of Skeletal Muscle Acetylcholine-gated Channel Clustering Positive Regulation Of Calcium Ion Import Across Plasma Membrane Dystroglycan Binding Voltage-gated Monoatomic Ion Channel Activity Positive Regulation Of Calcium Ion Transport Into Cytosol Regulation Of Developmental Growth Regulation Of Calcium Ion Import Across Plasma Membrane Positive Regulation Of Endoplasmic Reticulum Unfolded Protein Response Positive Regulation Of Receptor Clustering Meiotic Chromosome Segregation Mucus Secretion Regulation Of IRE1-mediated Unfolded Protein Response Regulation Of PERK-mediated Unfolded Protein Response Regulation Of Receptor Clustering Resolution Of Meiotic Recombination Intermediates Ectopic Germ Cell Programmed Cell Death Purinergic Nucleotide Receptor Signaling Pathway Regulation Of Calcium Ion Transport Into Cytosol Digestive Tract Morphogenesis Programmed Cell Death Involved In Cell Development Synaptonemal Complex Assembly	Regulation Of Lysosome Size Regulation Of Endosome Size Cytoplasmic Side Of Lysosomal Membrane BORC Complex Regulation Of Vesicle Size Lysosome Localization Organelle Transport Along Microtubule Transport Along Microtubule Microtubule-based Transport Establishment Of Organelle Localization Heart Development Regulation Of Cellular Component Size Cytoskeleton-dependent Intracellular Transport
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?