GGA3 and ARF1

Number of citations of the paper that reports this interaction (PMID 10747089)
101

Data Source:
HPRD (in vivo, in vitro, two hybrid)

		GGA3	ARF1
Gene Name		golgi-associated, gamma adaptin ear containing, ARF binding protein 3	ADP-ribosylation factor 1
Image
Gene Ontology Annotations	Cellular Component	Trans-Golgi Network Endosome Membrane Clathrin Adaptor Complex	Golgi Membrane Cytosol Plasma Membrane Focal Adhesion Postsynaptic Density Sarcomere Neuron Projection Postsynaptic Membrane Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	Protein Binding ADP-ribosylation Factor Binding	GTPase Activity Receptor Signaling Protein Activity Protein Binding GTP Binding Poly(A) RNA Binding
	Biological Process	Intracellular Protein Transport Vesicle-mediated Transport Positive Regulation Of Protein Catabolic Process	Regulation Of Receptor Internalization Phospholipid Metabolic Process Phosphatidylinositol Biosynthetic Process Cellular Copper Ion Homeostasis Retrograde Vesicle-mediated Transport, Golgi To ER Post-Golgi Vesicle-mediated Transport Small GTPase Mediated Signal Transduction Protein Transport Viral Process Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Regulation Of Arp2/3 Complex-mediated Actin Nucleation Small Molecule Metabolic Process COPI Coating Of Golgi Vesicle Regulation Of Defense Response To Virus By Virus Long Term Synaptic Depression Membrane Organization Dendritic Spine Organization
Pathways			Synthesis of PIPs at the Golgi membrane Metabolism of lipids and lipoproteins Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters HIV Infection Golgi Associated Vesicle Biogenesis Host Interactions of HIV factors The role of Nef in HIV-1 replication and disease pathogenesis Clathrin derived vesicle budding Lysosome Vesicle Biogenesis Golgi to ER Retrograde Transport MHC class II antigen presentation COPI Mediated Transport Phospholipid metabolism trans-Golgi Network Vesicle Budding Nef Mediated CD4 Down-regulation Adaptive Immune System PI Metabolism
Drugs
Diseases
GWAS
Protein-Protein Interactions		24 interactors: AFTPH AP1S2 ARF1 ARF3 BACE1 CDKN2A CLINT1 CLTC GGA1 GGA2 IGF2R M6PR PACS1 RAB5A RABEP1 RNF11 RPS27A STAB1 SYNRG TBC1D3 TSG101 UBC VPS11 VPS18	40 interactors: AP1B1 AP1G1 AP3B1 AP3D1 AP3S2 AP4E1 AP4M1 ARFGAP1 ARFIP1 ARFIP2 ARHGAP21 ASAP1 ASAP2 CHRM3 COPB1 COPE COPG1 CYTH1 CYTH2 EEF1G GGA1 GGA2 GGA3 GOSR2 INSR KDELR1 MDM4 NOA1 NPM1 PICK1 PIP5K1A PLD1 PLD2 PLEKHA8 PLIN2 RALA TMED10 TMED2 TMEM106A WBP11
Entrez ID		23163	375
HPRD ID		10443	00054
Ensembl ID		ENSG00000125447	ENSG00000143761
Uniprot IDs		A8K6I6 A8K6M0 Q9NZ52	P84077
PDB IDs		1JPL 1JUQ 1LF8 1P4U 1WR6 1YD8	1HUR 1RE0 1U81 3O47 4HMY
Enriched GO Terms of Interacting Partners?		Vesicle-mediated Transport Protein Transport Establishment Of Protein Localization Intracellular Transport Protein Localization Establishment Of Localization In Cell Transport Cellular Localization Intracellular Protein Transport Membrane Organization Viral Protein Processing Endocytosis Cellular Protein Localization Viral Process Virion Assembly Post-Golgi Vesicle-mediated Transport Endosomal Transport Regulation Of Defense Response To Virus By Virus Intracellular Transport Of Virus Antigen Processing And Presentation Of Peptide Antigen Golgi Vesicle Transport Antigen Processing And Presentation Receptor-mediated Endocytosis Viral Life Cycle Negative Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Cell Cycle Arrest Membrane Budding Regulation Of Defense Response To Virus Protein Processing Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Regulation Of Ubiquitin-protein Transferase Activity Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Regulation Of Cell Cycle Arrest Negative Regulation Of Protein Ubiquitination Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Notch Receptor Processing Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Glycogen Biosynthetic Process Regulation Of Vesicle-mediated Transport G1/S Transition Of Mitotic Cell Cycle Protein Polyubiquitination Cellular Polysaccharide Biosynthetic Process Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Polysaccharide Biosynthetic Process Receptor Internalization Negative Regulation Of Cell Cycle Negative Regulation Of Type I Interferon Production Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Protein Ubiquitination	Intracellular Protein Transport Intracellular Transport Establishment Of Localization In Cell Protein Transport Vesicle-mediated Transport Establishment Of Protein Localization Cellular Localization Cellular Protein Localization Protein Localization COPI-coated Vesicle Budding COPI Coating Of Golgi Vesicle Golgi Vesicle Budding Golgi Vesicle Transport Localization Within Membrane Establishment Of Vesicle Localization Vesicle Organization Vesicle Localization Transport Establishment Of Organelle Localization Vesicle Targeting, To, From Or Within Golgi Retrograde Vesicle-mediated Transport, Golgi To ER Organelle Localization Vesicle Targeting Membrane Organization Membrane Budding Organelle Organization Regulation Of ARF Protein Signal Transduction Cytoplasmic Transport Microtubule-based Transport Cytoskeleton-dependent Intracellular Transport Anterograde Synaptic Vesicle Transport Melanosome Organization Pigment Granule Organization Post-Golgi Vesicle-mediated Transport Anterograde Axon Cargo Transport ER To Golgi Vesicle-mediated Transport Regulation Of GTPase Activity Synaptic Vesicle Transport Antigen Processing And Presentation, Exogenous Lipid Antigen Via MHC Class Ib Positive Regulation Of NK T Cell Differentiation Establishment Of Golgi Localization Golgi To Vacuole Transport Regulation Of Ras Protein Signal Transduction Endosome To Melanosome Transport Cargo Loading Into Vesicle Pigment Granule Maturation Axon Cargo Transport Intra-Golgi Vesicle-mediated Transport Cellular Pigment Accumulation Cellular Pigmentation
Tagcloud ?		acylation adaptin adaptors anchored apart cargo catalytically dileucine doi endosome governing hyperubiquitinated implicate itch knocked ll localizes onc participating publication put really recruits ribosylation rnf11 traffic ubiquitination vhs	adp bulk close coated coatomer consumed contact copi dynamics endoplasmic exchange explored fission golgi governed gtpase interconnected maintain maintenance mitochondria mitochondrial powerhouse presumably produce proximity reticulum ribosylation thought vesicles
Tagcloud (Difference) ?		acylation adaptin adaptors anchored apart cargo catalytically dileucine doi endosome governing hyperubiquitinated implicate itch knocked ll localizes onc participating publication put really recruits rnf11 traffic ubiquitination vhs	adp bulk close coated coatomer consumed contact copi dynamics endoplasmic exchange explored fission golgi governed gtpase interconnected maintain maintenance mitochondria mitochondrial powerhouse presumably produce proximity reticulum thought vesicles
Tagcloud (Intersection) ?		ribosylation