GGA3 and CLINT1

Number of citations of the paper that reports this interaction (PubMedID 12858162)
0

Data Source:
BioGRID (unspecified method)

		GGA3	CLINT1
Description		golgi associated, gamma adaptin ear containing, ARF binding protein 3	clathrin interactor 1
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GO Annotations	Cellular Component	Lysosome Endosome Early Endosome Golgi Apparatus Trans-Golgi Network Endosome Membrane Membrane Early Endosome Membrane Protein-containing Complex Recycling Endosome Recycling Endosome Membrane	Nucleoplasm Cytoplasm Endosome Golgi Apparatus Cytosol Plasma Membrane Endomembrane System Membrane Clathrin Vesicle Coat Clathrin-coated Vesicle Cytoplasmic Vesicle Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Small GTPase Binding Phosphatidylinositol Binding Ubiquitin Binding Protein-containing Complex Binding Protein Transporter Activity	Protein Binding Phospholipid Binding Lipid Binding Clathrin Binding Cadherin Binding
	Biological Process	Protein Targeting To Lysosome Intracellular Protein Transport Golgi To Plasma Membrane Transport Protein Transport Vesicle-mediated Transport Protein Catabolic Process Regulation Of Protein Stability Protein Destabilization Endocytic Recycling Protein Localization To Cell Surface Golgi To Plasma Membrane Protein Transport Positive Regulation Of Protein Catabolic Process Protein Localization To Lysosome Negative Regulation Of Amyloid-beta Formation Positive Regulation Of Lysosomal Protein Catabolic Process	Endocytosis Clathrin Coat Assembly
Pathways		TBC/RABGAPs MET receptor recycling Amyloid fiber formation	Golgi Associated Vesicle Biogenesis
Drugs
Diseases
GWAS			Diastolic blood pressure ( 27841878) Pulse pressure ( 27841878) Systolic blood pressure ( 27841878)
Interacting Genes		45 interacting genes: ADRA2A ADRA2B AFTPH AP1G1 AP1S2 ARAP3 ARF1 ARF3 CDKN2A CLINT1 CLTC CYTH2 DAZAP2 EGFR ETS1 GGA1 GGA2 GTPBP4 IGF2R LITAF LRP10 M6PR NPM1 P4HA3 PACS1 PLEKHB2 PTGDR PTGDS RABEP1 RNF11 RNF214 RPS27A STAB1 SYNRG TBC1D3 TOLLIP TP53 TRAPPC6A TRIM23 TSG101 UBC UPRT VPS11 VPS18 ZNF497	14 interacting genes: AP1G1 AP2A1 AP2B1 CALM1 CEBPA CLTC DNM1 EPS15 GDPD5 GGA1 GGA2 GGA3 JUN YWHAG
Entrez ID		23163	9685
HPRD ID		10443	06273
Ensembl ID		ENSG00000125447	ENSG00000113282
Uniprot IDs		A8K6M0 B7Z456 Q9NZ52	A0A0S2Z4Y4 A0A0S2Z5H3 Q14677
PDB IDs		1JPL 1JUQ 1LF8 1P4U 1WR6 1YD8	1XGW 2QY7 2V8S
Enriched GO Terms of Interacting Partners?		Vesicle-mediated Transport Intracellular Protein Transport Cellular Localization Clathrin-coated Vesicle Endosome Establishment Of Localization In Cell Intracellular Transport Protein Transport Establishment Of Protein Localization Endosome Membrane Intracellular Protein Localization Early Endosome Golgi Apparatus AP-1 Adaptor Complex Endocytosis Trans-Golgi Network Membrane Trans-Golgi Network Lysosomal Transport Early Endosome Membrane Perinuclear Region Of Cytoplasm Import Into Cell Vacuolar Transport Autophagy Ubiquitin Protein Ligase Binding Endosome To Lysosome Transport Alpha2-adrenergic Receptor Activity Protein-containing Complex Golgi Membrane Protein Localization To Organelle Clathrin-coated Endocytic Vesicle Membrane Endocytic Vesicle Clathrin-coated Pit Disordered Domain Specific Binding Lysosomal Membrane Late Endosome Endomembrane System Negative Regulation Of Epinephrine Secretion Golgi Vesicle Transport Negative Regulation Of Norepinephrine Secretion Epinephrine Binding Clathrin Coat Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Clathrin Coat Of Trans-Golgi Network Vesicle CORVET Complex Ubiquitin Binding Post-Golgi Vesicle-mediated Transport Vesicle Organization Protein Localization To Ciliary Membrane Regulation Of Uterine Smooth Muscle Contraction Adrenergic Receptor Activity	Clathrin-coated Pit Post-Golgi Vesicle-mediated Transport Vesicle-mediated Transport Clathrin Coat Assembly Clathrin-coated Vesicle Vesicle-mediated Transport In Synapse Endocytosis Postsynaptic Neurotransmitter Receptor Internalization Presynaptic Endocytosis Postsynaptic Endocytic Zone Cytosolic Transport Golgi Vesicle Transport AP-2 Adaptor Complex Intracellular Protein Transport Establishment Of Protein Localization Receptor-mediated Endocytosis Import Into Cell Trans-Golgi Network Receptor Internalization Clathrin Adaptor Activity Endolysosome Membrane Establishment Of Localization In Cell Protein Transport Clathrin-coated Endocytic Vesicle Intracellular Transport Ubiquitin Binding Intracellular Protein Localization Membrane Coat Protein Localization To Cell Surface Clathrin-dependent Endocytosis Golgi To Plasma Membrane Protein Transport Vesicle-mediated Transport To The Plasma Membrane Negative Regulation Of Hyaluronan Biosynthetic Process Synaptic Vesicle Endocytosis Cellular Localization Clathrin Coat Clathrin Coat Of Trans-Golgi Network Vesicle Regulation Of Hyaluronan Biosynthetic Process Clathrin Coat Of Coated Pit Establishment Of Protein Localization To Plasma Membrane Golgi To Plasma Membrane Transport Protein-containing Complex Early Endosome Membrane Clathrin-coated Endocytic Vesicle Membrane Regulation Of Postsynaptic Membrane Neurotransmitter Receptor Levels Clathrin Adaptor Complex Endosomal Transport Golgi To Endosome Transport Small GTPase Binding Phosphatidylinositol Binding
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