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WDFY3 and PRMT1
Number of citations of the paper that reports this interaction (PubMedID
23455924
)
0
Data Source:
BioGRID
(two hybrid)
WDFY3
PRMT1
Description
WD repeat and FYVE domain containing 3
protein arginine methyltransferase 1
Image
GO Annotations
Cellular Component
Autophagosome Membrane
Nucleus
Nuclear Envelope
Nucleoplasm
Nucleolus
Cytoplasm
Autophagosome
Cytosol
Plasma Membrane
Membrane
Inclusion Body
PML Body
Axon
Nuclear Membrane
Atg12-Atg5-Atg16 Complex
Cell Projection
Perikaryon
Nucleus
Nucleoplasm
Cytoplasm
Lysosome
Lysosomal Membrane
Cytosol
Membrane
Methylosome
Molecular Function
Protein Binding
1-phosphatidylinositol Binding
Zinc Ion Binding
Lipid Binding
Metal Ion Binding
RNA Binding
Protein Binding
Methyltransferase Activity
N-methyltransferase Activity
Protein Methyltransferase Activity
Methyl-CpG Binding
Protein-arginine N-methyltransferase Activity
Transferase Activity
Enzyme Binding
Protein-arginine Omega-N Monomethyltransferase Activity
Protein-arginine Omega-N Asymmetric Methyltransferase Activity
Histone Methyltransferase Activity
Identical Protein Binding
Histone H4R3 Methyltransferase Activity
Mitogen-activated Protein Kinase P38 Binding
GATOR1 Complex Binding
Histone H4 Methyltransferase Activity
S-adenosyl-L-methionine Binding
Biological Process
Autophagy
Macroautophagy
Aggrephagy
Double-strand Break Repair Via Homologous Recombination
In Utero Embryonic Development
Chromatin Remodeling
Regulation Of DNA-templated Transcription
Protein Methylation
DNA Damage Response
Cell Surface Receptor Signaling Pathway
Positive Regulation Of Cell Population Proliferation
RNA Splicing
Negative Regulation Of Translation
Peptidyl-arginine Methylation
Viral Protein Processing
BMP Signaling Pathway
Regulation Of BMP Signaling Pathway
Negative Regulation Of BMP Signaling Pathway
Neuron Projection Development
Cellular Response To Nutrient Levels
Methylation
Cellular Response To Amino Acid Starvation
TORC1 Signaling
Positive Regulation Of Erythrocyte Differentiation
Regulation Of Megakaryocyte Differentiation
Negative Regulation Of Megakaryocyte Differentiation
Positive Regulation Of Translation
Negative Regulation Of Translational Initiation
Negative Regulation Of JNK Cascade
Positive Regulation Of Hemoglobin Biosynthetic Process
Cardiac Muscle Tissue Development
Protein Homooligomerization
Cellular Response To Methionine
Protein Localization To Lysosome
Membraneless Organelle Assembly
Positive Regulation Of P38MAPK Cascade
Negative Regulation Of TORC1 Signaling
Positive Regulation Of TORC1 Signaling
Positive Regulation Of Double-strand Break Repair Via Homologous Recombination
Negative Regulation Of Double-strand Break Repair Via Homologous Recombination
Pathways
RMTs methylate histone arginines
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
Extra-nuclear estrogen signaling
Estrogen-dependent gene expression
Maturation of nucleoprotein
Drugs
S-adenosyl-L-homocysteine
Diseases
GWAS
Cerebral amyloid deposition (PET imaging) (
26252872
)
Monocyte percentage of white cells (
32888494
)
Oropharynx cancer (
27749845
)
Schizophrenia (
29483656
)
Interacting Genes
16 interacting genes:
ATG5
BTG3
CEP76
GABARAPL1
GABARAPL2
GRB2
MAP1LC3C
MDFI
PRMT1
PRMT6
RABGAP1L
STAT3
SUV39H1
TNS2
TRIM39
ZBTB44
165 interacting genes:
AR
ARPC3
ASH2L
AXIN1
BRCA1
BTG1
BTG2
C4orf17
CAPRIN1
CDC37
CEBPA
CEP162
CIRBP
CNOT8
COIL
DAXX
DCAF16
DCAF8
DHX9
EP300
ESR1
EWSR1
FAM83D
FAM9A
FBL
FBXL17
FBXO7
FGF2
FLII
FUS
GLI1
GPATCH2L
GRHL3
GRIP1
H3C1
H4C1
H4C14
H4C16
HABP4
HNF4A
HNRNPA1
HNRNPA3
HNRNPK
HNRNPR
HNRNPU
HNRNPUL1
HROB
IDH3B
IFNAR1
IGSF21
ILF3
KHDRBS1
KHDRBS2
KHDRBS3
LRIF1
MAP3K5
MBD2
MBP
MECOM
MED31
MIR1-1
MIR1-2
MIR106A
MIR106B
MIR107
MIR10B
MIR122
MIR128-1
MIR138-1
MIR141
MIR143
MIR145
MIR155
MIR15A
MIR15B
MIR16-1
MIR16-2
MIR17
MIR18B
MIR199A1
MIR199A2
MIR19A
MIR19B1
MIR19B2
MIR200A
MIR200B
MIR206
MIR20A
MIR20B
MIR221
MIR222
MIR25
MIR29A
MIR29B1
MIR29B2
MIR29C
MIR34A
MIR34C
MIR363
MIR451A
MIR7-3
MIR9-1
MIR9-2
MIR9-3
MIR92A1
MIR92A2
MIRLET7A1
MIRLET7A2
MIRLET7A3
MIRLET7D
MIRLET7E
MIRLET7F1
MIRLET7F2
MLST8
NCOA1
NCOA2
NCOA3
NOL4
NRIP1
NTAQ1
OFCC1
PPARA
PPDPF
PRMT8
QKI
RBM15
RELA
RNF187
RPL37A
RPS29
RUNX1
S100A8
SAMD3
SHLD1
SIRT1
SPAG8
SPEG
SPSB1
SPSB2
SRSF1
STAT1
STAT5A
STUB1
SUPT5H
SYNCRIP
TBX6
TERF2
THRB
TK1
TOPORS
TP53
TRIM48
TUBB
UBE4B
USP11
VHL
VPS72
WDFY3
WDR33
YLPM1
YWHAG
ZBTB14
ZCCHC12
ZMYM5
ZNF451
Entrez ID
23001
3276
HPRD ID
10304
04257
Ensembl ID
ENSG00000163625
ENSG00000126457
Uniprot IDs
Q8IZQ1
Q99873
PDB IDs
3WIM
6W9N
6NT2
Enriched GO Terms of Interacting Partners
?
Cellular Response To Nitrogen Starvation
Cellular Response To Starvation
Response To Starvation
Cellular Response To Nutrient Levels
Mitophagy
Phosphatidylethanolamine Binding
Autophagy Of Mitochondrion
Autophagosome
Autophagosome Assembly
Autophagosome Organization
Cellular Response To Stress
Response To Nutrient Levels
Histone Methyltransferase Activity
Protein-arginine Omega-N Monomethyltransferase Activity
Histone H4R3 Methyltransferase Activity
Macroautophagy
Autophagosome Maturation
Protein-arginine Omega-N Asymmetric Methyltransferase Activity
Vacuole Organization
Autophagosome Membrane
Protein-arginine N-methyltransferase Activity
Negative Regulation Of Proteolysis Involved In Protein Catabolic Process
Aggrephagy
Response To Stress
GABA Receptor Binding
Autophagy
Negative Regulation Of Protein Metabolic Process
Phospholipid Binding
Histone H3 Methyltransferase Activity
Regulation Of Reactive Oxygen Species Metabolic Process
Negative Regulation Of Proteolysis
Protein-containing Complex Disassembly
Negative Regulation Of Catabolic Process
Organelle Assembly
Methyltransferase Activity
Positive Regulation Of Erythrocyte Differentiation
Regulation Of Megakaryocyte Differentiation
DNA Damage Response
Beta-tubulin Binding
Protein Sequestering Activity
Methylation
Cytoplasmic Vesicle
Guanyl-nucleotide Exchange Factor Adaptor Activity
GATOR1 Complex Binding
Histone H2AR3 Methyltransferase Activity
Regulation Of Erythrocyte Differentiation
Negative Regulation Of Macromolecule Metabolic Process
Regulation Of Myeloid Cell Differentiation
Cytoplasm
Negative Regulation Of Proteasomal Protein Catabolic Process
MiRNA-mediated Post-transcriptional Gene Silencing
Regulatory NcRNA-mediated Post-transcriptional Gene Silencing
RISC Complex
Post-transcriptional Gene Silencing
Regulatory NcRNA-mediated Gene Silencing
MRNA Base-pairing Post-transcriptional Repressor Activity
Post-transcriptional Regulation Of Gene Expression
Negative Regulation Of Gene Expression
Negative Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of Biosynthetic Process
MRNA 3'-UTR Binding
Negative Regulation Of Macromolecule Metabolic Process
Negative Regulation Of Metabolic Process
MiRNA-mediated Gene Silencing By Inhibition Of Translation
Regulation Of Gene Expression
Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of Translation
Regulation Of Macromolecule Metabolic Process
Regulation Of Metabolic Process
Extracellular Vesicle
Regulation Of Translation
MiRNA-mediated Gene Silencing By MRNA Destabilization
Regulation Of MRNA Metabolic Process
Negative Regulation Of Developmental Process
Regulation Of Angiogenesis
Negative Regulation Of Angiogenesis
Negative Regulation Of Vasculature Development
Regulation Of Vasculature Development
Negative Regulation Of Protein Metabolic Process
Regulation Of MRNA Stability
Regulation Of Blood Vessel Endothelial Cell Migration
Negative Regulation Of Vascular Endothelial Growth Factor Production
Regulation Of RNA Stability
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Positive Regulation Of RNA Metabolic Process
Positive Regulation Of MRNA Catabolic Process
Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Regulation Of Developmental Process
Positive Regulation Of Metabolic Process
Positive Regulation Of MRNA Metabolic Process
Positive Regulation Of Macromolecule Metabolic Process
Regulation Of Primary Metabolic Process
Regulation Of Programmed Cell Death
Regulation Of Multicellular Organismal Development
MRNA Destabilization
Negative Regulation Of Cell Differentiation
Regulation Of Anatomical Structure Morphogenesis
Regulation Of Cell Differentiation
Negative Regulation Of Cytokine Production
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