PRMT1 and HABP4

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (pull down)
HPRD (two hybrid)

		PRMT1	HABP4
Gene Name		protein arginine methyltransferase 1	hyaluronan binding protein 4
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol	Extracellular Region Nucleus Nucleoplasm Cytoplasm Cytosol Sarcomere
	Molecular Function	Protein Binding Methyltransferase Activity N-methyltransferase Activity Protein-arginine Omega-N Asymmetric Methyltransferase Activity Histone Methyltransferase Activity Identical Protein Binding Histone Methyltransferase Activity (H4-R3 Specific) Poly(A) RNA Binding	Protein Binding
	Biological Process	Chromatin Organization Regulation Of Transcription, DNA-templated Protein Methylation Cell Surface Receptor Signaling Pathway Histone Methylation Peptidyl-arginine Methylation Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine Neuron Projection Development Histone H4-R3 Methylation Negative Regulation Of Megakaryocyte Differentiation	Platelet Degranulation Transcription, DNA-templated Regulation Of Transcription, DNA-templated Blood Coagulation Platelet Activation Negative Regulation Of DNA Binding Cellular Response To Mechanical Stimulus
Pathways		Chromatin modifying enzymes Chromatin organization RMTs methylate histone arginines	Response to elevated platelet cytosolic Ca2+ Platelet degranulation Platelet activation, signaling and aggregation
Drugs
Diseases
GWAS
Protein-Protein Interactions		93 interactors: AR ARPC3 ASH2L AXIN1 BRCA1 BTG1 BTG2 C17orf53 C20orf196 C4orf17 CAPRIN1 CDC37 CEP162 CIRBP CNOT8 COIL DAXX DCAF16 DCAF8 DHX9 EIF4A1 ESR1 EWSR1 FAM83D FAM9A FBL FGF2 FLII FUS GPATCH2L GRHL3 GRIP1 HABP4 HIST1H3A HIST1H4A HIST2H4A HIST4H4 HNF4A HNRNPA1 HNRNPK HNRNPR HNRNPU HNRNPUL1 IDH3B IFNAR1 IGSF21 ILF3 KHDRBS1 KHDRBS2 KHDRBS3 LRIF1 MBP MECOM MED31 MLST8 NCOA1 NCOA2 NCOA3 NOL4 NRIP1 OFCC1 PIAS1 PPARA PRMT8 QKI RELA RNF187 RUNX1 S100A8 SAMD3 SPAG8 SPEG SPSB1 SPSB2 STAT1 STAT5A SUPT5H SYNCRIP TAF15 TBX6 TERF2 THRB TP53 VHL VPS72 WDFY3 WDR33 WDYHV1 YLPM1 YWHAG ZBTB14 ZMYM5 ZNF451	24 interactors: C1QBP CHD3 DAXX ENO2 FRA10AC1 GNB2L1 HMGXB4 KAT5 PIAS3 PPP1R15A PRKCA PRKCB PRKCD PRKCG PRKCQ PRKCZ PRMT1 SRSF9 SYNCRIP TOPORS TP53 UBE2I VIM YBX1
Entrez ID		3276	22927
HPRD ID		04257	13628
Ensembl ID		ENSG00000126457	ENSG00000130956
Uniprot IDs		B4DJ87 H7C2I1 Q99873	Q5JVS0
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Gene Expression Gene Expression Nucleobase-containing Compound Metabolic Process RNA Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nitrogen Compound Metabolic Process Positive Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Cellular Metabolic Process Intracellular Receptor Signaling Pathway Regulation Of Transcription From RNA Polymerase II Promoter Cellular Macromolecule Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Macromolecule Biosynthetic Process Positive Regulation Of Metabolic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Androgen Receptor Signaling Pathway Intracellular Steroid Hormone Receptor Signaling Pathway Negative Regulation Of Cellular Metabolic Process Biosynthetic Process Transcription From RNA Polymerase II Promoter Regulation Of Cellular Process MRNA Processing Chromatin Organization Cellular Process Chromatin Modification Response To Hormone MRNA Metabolic Process RNA Processing Chromosome Organization Cellular Response To Hormone Stimulus Metabolic Process Response To Organic Substance	Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Protein Metabolic Process Negative Regulation Of Insulin Receptor Signaling Pathway Apoptotic Process Programmed Cell Death Negative Regulation Of Cellular Metabolic Process Cell Death Death Regulation Of Protein Metabolic Process Regulation Of Insulin Receptor Signaling Pathway Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Metabolic Process Blood Coagulation Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Modification Process Hemostasis Regulation Of Cellular Response To Insulin Stimulus Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Signal Transduction Platelet Activation Viral Process Regulation Of Body Fluid Levels Negative Regulation Of Signaling Wound Healing Peptidyl-amino Acid Modification Regulation Of RNA Metabolic Process Response To Wounding Chromatin Organization Intracellular Signal Transduction Regulation Of Apoptotic Process Regulation Of Platelet Aggregation Positive Regulation Of Phospholipase Activity Regulation Of Cell Death Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Phospholipase Activity Histone H3-T6 Phosphorylation Positive Regulation Of Lipase Activity Chromatin Modification Enzyme Linked Receptor Protein Signaling Pathway Organelle Organization Positive Regulation Of Signal Transduction Regulation Of Peptidyl-tyrosine Phosphorylation Regulation Of Cellular Amino Acid Metabolic Process Negative Regulation Of Gene Expression Negative Regulation Of Cell Death Protein Sumoylation
Tagcloud ?		bbrd brucei clade clades connects dart dihydrolipoamide exemplified fmr homologues methyltransferases outgroup paralogue phylogeny prmt2 prmt3 prmt4 prmt5 prmt6 prmt7 prmt8 prmt9 prmts reconstructing resolve tbprmts tedious trypanosoma uncharacterized	9q altered cgi contexts experimentally explain familiar functionally give haplotype hek293t identity inducer insights ki knockdown link microchip overexpression paralogs prompting qrt serbp1 shared similarity sirna thapsigargin transcriptome tumorigenic
Tagcloud (Difference) ?		bbrd brucei clade clades connects dart dihydrolipoamide exemplified fmr homologues methyltransferases outgroup paralogue phylogeny prmt2 prmt3 prmt4 prmt5 prmt6 prmt7 prmt8 prmt9 prmts reconstructing resolve tbprmts tedious trypanosoma uncharacterized	9q altered cgi contexts experimentally explain familiar functionally give haplotype hek293t identity inducer insights ki knockdown link microchip overexpression paralogs prompting qrt serbp1 shared similarity sirna thapsigargin transcriptome tumorigenic
Tagcloud (Intersection) ?