PRMT1 and DCAF8

Number of citations of the paper that reports this interaction (PMID 23455924)
3

Data Source:
BioGRID (two hybrid)

		PRMT1	DCAF8
Gene Name		protein arginine methyltransferase 1	DDB1 and CUL4 associated factor 8
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol	Nucleus Cytoplasm Cul4-RING E3 Ubiquitin Ligase Complex
	Molecular Function	Protein Binding Methyltransferase Activity N-methyltransferase Activity Protein-arginine Omega-N Asymmetric Methyltransferase Activity Histone Methyltransferase Activity Identical Protein Binding Histone Methyltransferase Activity (H4-R3 Specific) Poly(A) RNA Binding	Protein Binding
	Biological Process	Chromatin Organization Regulation Of Transcription, DNA-templated Protein Methylation Cell Surface Receptor Signaling Pathway Histone Methylation Peptidyl-arginine Methylation Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine Neuron Projection Development Histone H4-R3 Methylation Negative Regulation Of Megakaryocyte Differentiation	Protein Ubiquitination
Pathways		Chromatin modifying enzymes Chromatin organization RMTs methylate histone arginines
Drugs
Diseases
GWAS
Protein-Protein Interactions		93 interactors: AR ARPC3 ASH2L AXIN1 BRCA1 BTG1 BTG2 C17orf53 C20orf196 C4orf17 CAPRIN1 CDC37 CEP162 CIRBP CNOT8 COIL DAXX DCAF16 DCAF8 DHX9 EIF4A1 ESR1 EWSR1 FAM83D FAM9A FBL FGF2 FLII FUS GPATCH2L GRHL3 GRIP1 HABP4 HIST1H3A HIST1H4A HIST2H4A HIST4H4 HNF4A HNRNPA1 HNRNPK HNRNPR HNRNPU HNRNPUL1 IDH3B IFNAR1 IGSF21 ILF3 KHDRBS1 KHDRBS2 KHDRBS3 LRIF1 MBP MECOM MED31 MLST8 NCOA1 NCOA2 NCOA3 NOL4 NRIP1 OFCC1 PIAS1 PPARA PRMT8 QKI RELA RNF187 RUNX1 S100A8 SAMD3 SPAG8 SPEG SPSB1 SPSB2 STAT1 STAT5A SUPT5H SYNCRIP TAF15 TBX6 TERF2 THRB TP53 VHL VPS72 WDFY3 WDR33 WDYHV1 YLPM1 YWHAG ZBTB14 ZMYM5 ZNF451	9 interactors: DDB1 GTPBP3 MDFI PRMT1 PRMT8 RAF1 RBPMS SUV39H1 THAP1
Entrez ID		3276	50717
HPRD ID		04257	18300
Ensembl ID		ENSG00000126457	ENSG00000132716
Uniprot IDs		B4DJ87 H7C2I1 Q99873	B7Z8C9 Q5TAQ9
PDB IDs			3I8E
Enriched GO Terms of Interacting Partners?		Regulation Of Gene Expression Gene Expression Nucleobase-containing Compound Metabolic Process RNA Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nitrogen Compound Metabolic Process Positive Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Cellular Metabolic Process Intracellular Receptor Signaling Pathway Regulation Of Transcription From RNA Polymerase II Promoter Cellular Macromolecule Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Macromolecule Biosynthetic Process Positive Regulation Of Metabolic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Androgen Receptor Signaling Pathway Intracellular Steroid Hormone Receptor Signaling Pathway Negative Regulation Of Cellular Metabolic Process Biosynthetic Process Transcription From RNA Polymerase II Promoter Regulation Of Cellular Process MRNA Processing Chromatin Organization Cellular Process Chromatin Modification Response To Hormone MRNA Metabolic Process RNA Processing Chromosome Organization Cellular Response To Hormone Stimulus Metabolic Process Response To Organic Substance	Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine Histone Modification Peptidyl-arginine N-methylation Histone Methylation Histone H4-R3 Methylation Histone Arginine Methylation Peptidyl-arginine Methylation Protein Methylation Chromatin Modification Chromatin Organization Chromosome Organization Death-inducing Signaling Complex Assembly Methylation Regulation Of Nitrogen Compound Metabolic Process Cellular Metabolic Process Positive Regulation By Virus Of Viral Protein Levels In Host Cell Regulation Of Transcription, DNA-templated Regulation Of Protein Import Into Nucleus Negative Regulation Of Megakaryocyte Differentiation Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Protein Phosphorylation Regulation Of RNA Metabolic Process Regulation Of Protein Localization To Nucleus Histone H3-K9 Dimethylation UV-damage Excision Repair Regulation Of Nucleocytoplasmic Transport Positive Regulation Of Viral Release From Host Cell MAPK Cascade Organelle Organization Positive Regulation Of Phosphorylation Cellular Protein Modification Process Negative Regulation Of Hematopoietic Progenitor Cell Differentiation Regulation Of Gene Expression Positive Regulation Of Protein Modification Process Regulation Of Binding Regulation Of Intracellular Protein Transport Histone H3-K9 Trimethylation Peptidyl-amino Acid Modification Activation Of Protein Kinase Activity Peptidyl-lysine Dimethylation Histone H2A Monoubiquitination Signal Transduction By Phosphorylation Response To Hypoxia Positive Regulation Of SMAD Protein Import Into Nucleus Regulation Of Metabolic Process Histone H2A Ubiquitination Regulation Of Protein Phosphorylation Chromatin Silencing At RDNA Regulation Of SMAD Protein Import Into Nucleus
Tagcloud ?		bbrd brucei clade clades connects dart dihydrolipoamide exemplified fmr homologues methyltransferases outgroup paralogue phylogeny prmt2 prmt3 prmt4 prmt5 prmt6 prmt7 prmt8 prmt9 prmts reconstructing resolve tbprmts tedious trypanosoma uncharacterized
Tagcloud (Difference) ?		bbrd brucei clade clades connects dart dihydrolipoamide exemplified fmr homologues methyltransferases outgroup paralogue phylogeny prmt2 prmt3 prmt4 prmt5 prmt6 prmt7 prmt8 prmt9 prmts reconstructing resolve tbprmts tedious trypanosoma uncharacterized
Tagcloud (Intersection) ?