WDFY3 and RABGAP1L

Number of citations of the paper that reports this interaction (PubMedID 25814554)
62

Data Source:
BioGRID (two hybrid)

		WDFY3	RABGAP1L
Description		WD repeat and FYVE domain containing 3	RAB GTPase activating protein 1 like
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GO Annotations	Cellular Component	Autophagosome Membrane Nucleus Nuclear Envelope Nucleoplasm Nucleolus Cytoplasm Autophagosome Cytosol Plasma Membrane Membrane Inclusion Body PML Body Axon Nuclear Membrane Atg12-Atg5-Atg16 Complex Cell Projection Perikaryon	Nucleus Cytoplasm Endosome Early Endosome Golgi Apparatus Cytoplasmic Vesicle
	Molecular Function	Protein Binding 1-phosphatidylinositol Binding Zinc Ion Binding Lipid Binding Metal Ion Binding	GTPase Activator Activity Protein Binding Small GTPase Binding
	Biological Process	Autophagy Macroautophagy Aggrephagy	Endocytosis Protein Transport Regulation Of Protein Localization
Pathways
Drugs
Diseases
GWAS		Cerebral amyloid deposition (PET imaging) ( 26252872) Monocyte percentage of white cells ( 32888494) Oropharynx cancer ( 27749845)	Adult body size ( 32376654) Caffeine consumption from coffee or tea ( 33287642) Caffeine consumption from tea ( 33287642) Cerebrospinal fluid t-tau:AB1-42 ratio ( 26252872) Chronotype ( 30696823) Daytime nap ( 33568662) Femur bone mineral density x serum urate levels interaction ( 34046847) Medication use (anilides) ( 31015401) Neutrophil count ( 32888494) Systemic lupus erythematosus ( 26606652 33536424) Tea consumption ( 31046077) White blood cell count ( 32888494)
Interacting Genes		16 interacting genes: ATG5 BTG3 CEP76 GABARAPL1 GABARAPL2 GRB2 MAP1LC3C MDFI PRMT1 PRMT6 RABGAP1L STAT3 SUV39H1 TNS2 TRIM39 ZBTB44	12 interacting genes: ACAP1 ARFGAP1 DBN1 GABARAPL1 MAP1LC3A RAB13 RAB34 RAB36 RB1 TSPAN2 UQCC2 WDFY3
Entrez ID		23001	9910
HPRD ID		10304	16464
Ensembl ID		ENSG00000163625	ENSG00000152061
Uniprot IDs		Q8IZQ1	A0A0U1RRM5 A0A804HKD7 B7ZAP0 F1LJ00 F5H8L0 Q5R372 Q9UEL5 Q9Y3L8
PDB IDs		3WIM 6W9N	3HZJ
Enriched GO Terms of Interacting Partners?		Cellular Response To Nitrogen Starvation Cellular Response To Starvation Response To Starvation Cellular Response To Nutrient Levels Mitophagy Phosphatidylethanolamine Binding Autophagy Of Mitochondrion Autophagosome Autophagosome Assembly Autophagosome Organization Cellular Response To Stress Response To Nutrient Levels Histone Methyltransferase Activity Protein-arginine Omega-N Monomethyltransferase Activity Histone H4R3 Methyltransferase Activity Macroautophagy Autophagosome Maturation Protein-arginine Omega-N Asymmetric Methyltransferase Activity Vacuole Organization Autophagosome Membrane Protein-arginine N-methyltransferase Activity Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Aggrephagy Response To Stress GABA Receptor Binding Autophagy Negative Regulation Of Protein Metabolic Process Phospholipid Binding Histone H3 Methyltransferase Activity Regulation Of Reactive Oxygen Species Metabolic Process Negative Regulation Of Proteolysis Protein-containing Complex Disassembly Negative Regulation Of Catabolic Process Organelle Assembly Methyltransferase Activity Positive Regulation Of Erythrocyte Differentiation Regulation Of Megakaryocyte Differentiation DNA Damage Response Beta-tubulin Binding Protein Sequestering Activity Methylation Cytoplasmic Vesicle Guanyl-nucleotide Exchange Factor Adaptor Activity GATOR1 Complex Binding Histone H2AR3 Methyltransferase Activity Regulation Of Erythrocyte Differentiation Negative Regulation Of Macromolecule Metabolic Process Regulation Of Myeloid Cell Differentiation Cytoplasm Negative Regulation Of Proteasomal Protein Catabolic Process	Autophagosome Autophagosome Membrane Cellular Response To Nitrogen Starvation Phosphatidylethanolamine Binding Macroautophagy Intracellular Protein Localization Protein Transport Trans-Golgi Network To Recycling Endosome Transport Mitophagy Autophagosome Maturation Golgi To Plasma Membrane Transport Positive Regulation Of Receptor Localization To Synapse Cell Communication By Chemical Coupling Membrane GTPase Activity Cellular Response To Insulin Stimulus Establishment Of Protein Localization GTP Binding Post-Golgi Vesicle-mediated Transport Plasma Membrane Bounded Cell Projection Organization Cytoplasmic Vesicle Recycling Endosome Membrane Protein Localization To Cell Leading Edge Golgi Apparatus Establishment Of Sertoli Cell Barrier Regulation Of Smoothened Signaling Pathway Ubiquitin Protein Ligase Binding Sister Chromatid Biorientation Maintenance Of Mitotic Sister Chromatid Cohesion Regulation Of Lipid Kinase Activity PML Body Chromatin Lock Complex Positive Regulation Of Collagen Fibril Organization Microglia Development Autophagy Autophagosome Organization Autophagy Of Mitochondrion Autophagosome Assembly Cellular Response To Oxygen-glucose Deprivation Phospholipid Binding
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