PRMT1 and BTG1

Number of citations of the paper that reports this interaction (PMID 8663146)
89

Data Source:
BioGRID (pull down)
HPRD (in vitro, two hybrid)

		PRMT1	BTG1
Gene Name		protein arginine methyltransferase 1	B-cell translocation gene 1, anti-proliferative
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol	Nucleus Cytoplasm
	Molecular Function	Protein Binding Methyltransferase Activity N-methyltransferase Activity Protein-arginine Omega-N Asymmetric Methyltransferase Activity Histone Methyltransferase Activity Identical Protein Binding Histone Methyltransferase Activity (H4-R3 Specific) Poly(A) RNA Binding	Transcription Cofactor Activity Protein Binding Enzyme Binding Kinase Binding
	Biological Process	Chromatin Organization Regulation Of Transcription, DNA-templated Protein Methylation Cell Surface Receptor Signaling Pathway Histone Methylation Peptidyl-arginine Methylation Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine Neuron Projection Development Histone H4-R3 Methylation Negative Regulation Of Megakaryocyte Differentiation	Regulation Of Transcription, DNA-templated Negative Regulation Of Cell Proliferation Cell Migration Negative Regulation Of Cell Growth Positive Regulation Of Endothelial Cell Differentiation Positive Regulation Of Myoblast Differentiation Positive Regulation Of Angiogenesis Positive Regulation Of Fibroblast Apoptotic Process
Pathways		Chromatin modifying enzymes Chromatin organization RMTs methylate histone arginines
Drugs
Diseases
GWAS			Heart failure ( 20445134)
Protein-Protein Interactions		93 interactors: AR ARPC3 ASH2L AXIN1 BRCA1 BTG1 BTG2 C17orf53 C20orf196 C4orf17 CAPRIN1 CDC37 CEP162 CIRBP CNOT8 COIL DAXX DCAF16 DCAF8 DHX9 EIF4A1 ESR1 EWSR1 FAM83D FAM9A FBL FGF2 FLII FUS GPATCH2L GRHL3 GRIP1 HABP4 HIST1H3A HIST1H4A HIST2H4A HIST4H4 HNF4A HNRNPA1 HNRNPK HNRNPR HNRNPU HNRNPUL1 IDH3B IFNAR1 IGSF21 ILF3 KHDRBS1 KHDRBS2 KHDRBS3 LRIF1 MBP MECOM MED31 MLST8 NCOA1 NCOA2 NCOA3 NOL4 NRIP1 OFCC1 PIAS1 PPARA PRMT8 QKI RELA RNF187 RUNX1 S100A8 SAMD3 SPAG8 SPEG SPSB1 SPSB2 STAT1 STAT5A SUPT5H SYNCRIP TAF15 TBX6 TERF2 THRB TP53 VHL VPS72 WDFY3 WDR33 WDYHV1 YLPM1 YWHAG ZBTB14 ZMYM5 ZNF451	12 interactors: CCNA2 CNOT7 CNOT8 HOXB9 PRMT1 RARA RNF181 SKP2 THRA THRB TUBA1A XRCC6
Entrez ID		3276	694
HPRD ID		04257	15912
Ensembl ID		ENSG00000126457
Uniprot IDs		B4DJ87 H7C2I1 Q99873	P62324 Q6IBC8
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Gene Expression Gene Expression Nucleobase-containing Compound Metabolic Process RNA Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nitrogen Compound Metabolic Process Positive Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Cellular Metabolic Process Intracellular Receptor Signaling Pathway Regulation Of Transcription From RNA Polymerase II Promoter Cellular Macromolecule Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Macromolecule Biosynthetic Process Positive Regulation Of Metabolic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Androgen Receptor Signaling Pathway Intracellular Steroid Hormone Receptor Signaling Pathway Negative Regulation Of Cellular Metabolic Process Biosynthetic Process Transcription From RNA Polymerase II Promoter Regulation Of Cellular Process MRNA Processing Chromatin Organization Cellular Process Chromatin Modification Response To Hormone MRNA Metabolic Process RNA Processing Chromosome Organization Cellular Response To Hormone Stimulus Metabolic Process Response To Organic Substance	Female Courtship Behavior Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Female Receptivity Positive Regulation Of Cellular Metabolic Process Female Mating Behavior Type I Pneumocyte Differentiation Steroid Hormone Mediated Signaling Pathway Negative Regulation Of Gene Expression Regulation Of Transcription, DNA-templated G2/M Transition Of Mitotic Cell Cycle Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Cell Proliferation Regulation Of RNA Metabolic Process Transcription, DNA-templated Hormone-mediated Signaling Pathway Positive Regulation Of MRNA Catabolic Process RNA Biosynthetic Process Positive Regulation Of Metabolic Process Nuclear-transcribed MRNA Poly(A) Tail Shortening Response To Steroid Hormone Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Transcription Initiation From RNA Polymerase II Promoter Mating Behavior Regulation Of Gene Expression Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic Regulation Of Nitrogen Compound Metabolic Process Cellular Response To Steroid Hormone Stimulus RNA Phosphodiester Bond Hydrolysis, Exonucleolytic Cellular Response To Stimulus Intracellular Receptor Signaling Pathway Regulation Of Transcription From RNA Polymerase II Promoter Gene Silencing By MiRNA DNA-templated Transcription, Initiation Posttranscriptional Gene Silencing Mating Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Lung Epithelial Cell Differentiation Regulation Of Translation Respiratory System Development RNA Metabolic Process Lung Cell Differentiation Lung Epithelium Development Gene Silencing By RNA
Tagcloud ?		bbrd brucei clade clades connects dart dihydrolipoamide exemplified fmr homologues methyltransferases outgroup paralogue phylogeny prmt2 prmt3 prmt4 prmt5 prmt6 prmt7 prmt8 prmt9 prmts reconstructing resolve tbprmts tedious trypanosoma uncharacterized	accompanied achn adjacent bcell biopsies biopsy blotting empty endoscopic fraction g0 immediately indicator kidney lebtg1 leempty lentivirus lymphoma metalloproteinase proportion regulator respect serve stably transfected utilizing vectortransfected vs
Tagcloud (Difference) ?		bbrd brucei clade clades connects dart dihydrolipoamide exemplified fmr homologues methyltransferases outgroup paralogue phylogeny prmt2 prmt3 prmt4 prmt5 prmt6 prmt7 prmt8 prmt9 prmts reconstructing resolve tbprmts tedious trypanosoma uncharacterized	accompanied achn adjacent bcell biopsies biopsy blotting empty endoscopic fraction g0 immediately indicator kidney lebtg1 leempty lentivirus lymphoma metalloproteinase proportion regulator respect serve stably transfected utilizing vectortransfected vs
Tagcloud (Intersection) ?