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CCT5 and SUMO4
Number of citations of the paper that reports this interaction (PubMedID
16236267
)
0
Data Source:
HPRD
(in vivo)
CCT5
SUMO4
Description
chaperonin containing TCP1 subunit 5
small ubiquitin like modifier 4
Image
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Centrosome
Cytosol
Chaperonin-containing T-complex
Cytoskeleton
Microtubule
Cell Body
Extracellular Exosome
Nucleus
SUMO Ligase Complex
Molecular Function
Nucleotide Binding
MRNA 3'-UTR Binding
Protein Binding
ATP Binding
Hydrolase Activity
ATP Hydrolysis Activity
G-protein Beta-subunit Binding
Protein Folding Chaperone
MRNA 5'-UTR Binding
Beta-tubulin Binding
Unfolded Protein Binding
ATP-dependent Protein Folding Chaperone
Protein Tag Activity
Ubiquitin-like Protein Ligase Binding
Biological Process
Protein Folding
Binding Of Sperm To Zona Pellucida
Response To Virus
Positive Regulation Of Telomere Maintenance Via Telomerase
Protein Stabilization
Positive Regulation Of Protein Localization To Cajal Body
Positive Regulation Of Telomerase RNA Localization To Cajal Body
Protein Sumoylation
Cellular Response To Oxidative Stress
Regulation Of Canonical NF-kappaB Signal Transduction
Positive Regulation Of DNA Binding
Negative Regulation Of DNA Binding
Negative Regulation Of DNA-templated Transcription
Regulation Of Protein Localization To Nucleus
Pathways
Prefoldin mediated transfer of substrate to CCT/TriC
Formation of tubulin folding intermediates by CCT/TriC
Folding of actin by CCT/TriC
Association of TriC/CCT with target proteins during biosynthesis
Association of TriC/CCT with target proteins during biosynthesis
BBSome-mediated cargo-targeting to cilium
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding
Drugs
Diseases
GWAS
Metabolite levels (
23823483
)
Pain (
22956598
)
Dupuytren's disease (
28886342
)
Interacting Genes
23 interacting genes:
ACTA1
ACTA2
ACTB
CEBPA
DCAF12
DUXAP9
ELP1
ERCC6
HDAC3
IMMT
MCPH1
OGT
PDCL
SPMAP2
SUMO2
SUMO4
TBC1D17
TCP1
TERT
TP53
VHL
XRN1
ZNRD2
75 interacting genes:
ACADM
ACO2
ACTG1
ALDOA
ARHGDIA
ATP5F1B
CALR
CAT
CCT2
CCT5
CCT6A
CCT7
CLIC1
DNAJA1
DNAJB11
EIF3I
ENO1
ENO2
FOS
G6PD
GAPDH
GMPS
GSTP1
HNRNPD
HNRNPF
HNRNPH1
HNRNPL
HSPA1B
HSPA5
HSPA8
HSPA9
HSPD1
IDH1
IDH3A
IMPDH2
JUN
LDHB
LMNA
LMNB1
MRPS22
NFKBIA
NR3C1
PA2G4
PAFAH1B3
PDIA3
PDIA6
PGK1
PHB1
PHGDH
PITHD1
PPA1
PRDX2
PRDX3
PRDX4
PRDX6
PRPS1
PSMC2
RACK1
RPSA
SF3B4
SPINT2
STAT1
STAT3
STIP1
STOML2
STRAP
TFAP2A
TOP2A
TPM3
TUBA1C
TXNL1
UBE2V1
VCP
VDAC1
ZPR1
Entrez ID
22948
387082
HPRD ID
06468
10584
Ensembl ID
ENSG00000150753
ENSG00000177688
Uniprot IDs
B4DDU6
B4DX08
B4DYC8
B7ZAR1
E7ENZ3
E9PCA1
P48643
V9HW37
Q6EEV6
PDB IDs
5UYX
5UYZ
6NR8
6NR9
6NRA
6NRB
6NRC
6NRD
6QB8
7LUM
7LUP
7NVL
7NVM
7NVN
7NVO
7TRG
7TTN
7TTT
7TUB
7WU7
7WZ3
7X0A
7X0S
7X0V
7X3J
7X3U
7X6Q
7X7Y
8AJM
8AJO
8HKI
8I1U
8I9U
8IB8
8SFE
8SFF
8SG8
8SG9
8SGC
8SGL
8SGQ
8SH9
8SHA
8SHD
8SHE
8SHF
8SHG
8SHL
8SHN
8SHO
8SHP
8SHQ
8SHT
Enriched GO Terms of Interacting Partners
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Positive Regulation Of Biosynthetic Process
Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Macromolecule Metabolic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Regulation Of Macromolecule Metabolic Process
Regulation Of Gene Expression
Mesenchyme Migration
Regulation Of Nucleobase-containing Compound Metabolic Process
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of Chromosome Organization
Positive Regulation Of RNA Metabolic Process
Regulation Of Telomere Maintenance Via Telomerase
Regulation Of Telomere Maintenance Via Telomere Lengthening
Regulation Of Protein Localization To Nucleus
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Positive Regulation Of Metabolic Process
Positive Regulation Of DNA-templated Transcription Initiation
Regulation Of Protein Stability
Regulation Of Metabolic Process
Cell Body
Positive Regulation Of RNA Biosynthetic Process
Positive Regulation Of DNA-templated Transcription
Regulation Of DNA-templated Transcription Initiation
Protein Tag Activity
Replicative Senescence
Regulation Of Stem Cell Proliferation
Regulation Of DNA Biosynthetic Process
Chromatin DNA Binding
Regulation Of Primary Metabolic Process
Positive Regulation Of Protein Localization To Nucleus
Regulation Of Cell Cycle
Mitochondrion Organization
Negative Regulation Of Telomere Maintenance Via Telomerase
PML Body
Regulation Of Telomere Maintenance
Telomerase RNA Binding
Regulation Of DNA Metabolic Process
Regulation Of Protein Metabolic Process
Ubiquitin-like Protein Ligase Binding
Regulation Of RNA Metabolic Process
Negative Regulation Of Stem Cell Proliferation
Response To X-ray
Nuclear Matrix
Histone Deacetylase Binding
Negative Regulation Of Telomere Maintenance Via Telomere Lengthening
Negative Regulation Of DNA Biosynthetic Process
Circadian Rhythm
Negative Regulation Of DNA Metabolic Process
Cellular Response To Hypoxia
Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Extracellular Exosome
Protein Folding
ATP-dependent Protein Folding Chaperone
Unfolded Protein Binding
Protein Folding Chaperone
Cytoplasm
Purine Nucleotide Metabolic Process
Cytosol
Nucleotide Metabolic Process
Ubiquitin Protein Ligase Binding
Ribose Phosphate Metabolic Process
Regulation Of Apoptotic Process
Ficolin-1-rich Granule Lumen
Purine-containing Compound Metabolic Process
Regulation Of Programmed Cell Death
Identical Protein Binding
RNA Binding
Nucleoside Phosphate Metabolic Process
Nicotinamide Nucleotide Metabolic Process
Protein Refolding
ATP Metabolic Process
Secretory Granule Lumen
Purine Ribonucleotide Metabolic Process
Nucleobase-containing Small Molecule Metabolic Process
Peroxiredoxin Activity
Ribonucleotide Metabolic Process
Hydrogen Peroxide Catabolic Process
Negative Regulation Of Apoptotic Process
Nucleobase-containing Compound Metabolic Process
Cellular Response To Cytokine Stimulus
Negative Regulation Of Programmed Cell Death
Positive Regulation Of Telomerase RNA Localization To Cajal Body
Mitochondrion
Positive Regulation Of Telomere Maintenance Via Telomerase
Oxidoreductase Activity
Antioxidant Activity
Positive Regulation Of Protein Localization To Cajal Body
Chaperonin-containing T-complex
Positive Regulation Of Telomere Maintenance Via Telomere Lengthening
Ribonucleoprotein Complex
Small Molecule Metabolic Process
Generation Of Precursor Metabolites And Energy
Response To Peptide
Enzyme Binding
Regulation Of Telomerase RNA Localization To Cajal Body
Peroxidase Activity
Nucleus
Hydrogen Peroxide Metabolic Process
Response To Stress
Organophosphate Metabolic Process
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