CCT5 and IMMT

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		CCT5	IMMT
Gene Name		chaperonin containing TCP1, subunit 5 (epsilon)	inner membrane protein, mitochondrial
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Zona Pellucida Receptor Complex Nucleolus Cytoplasm Centrosome Cytosol Chaperonin-containing T-complex Microtubule Cell Body Extracellular Vesicular Exosome	Mitochondrion Mitochondrial Inner Membrane Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding ATP Binding G-protein Beta-subunit Binding Beta-tubulin Binding Unfolded Protein Binding	Protein Binding Poly(A) RNA Binding
	Biological Process	Protein Folding Binding Of Sperm To Zona Pellucida Response To Virus Cellular Protein Metabolic Process 'de Novo' Posttranslational Protein Folding Toxin Transport	Biological_process Response To Cold Mitochondrial Calcium Ion Homeostasis
Pathways		Cargo trafficking to the periciliary membrane Protein folding Organelle biogenesis and maintenance Prefoldin mediated transfer of substrate to CCT/TriC Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding Association of TriC/CCT with target proteins during biosynthesis Chaperonin-mediated protein folding Assembly of the primary cilium BBSome-mediated cargo-targeting to cilium Formation of tubulin folding intermediates by CCT/TriC Folding of actin by CCT/TriC
Drugs
Diseases
GWAS		Pain ( 22956598)
Protein-Protein Interactions		15 interactors: ACTA1 ACTA2 ACTB HDAC3 IKBKAP IMMT PDCL SSSCA1 SUMO4 TBC1D17 TCP1 TERT THEG TP53 XRN1	58 interactors: AKTIP ALB ARMCX3 ASCC2 ATXN1 BAG6 BMI1 C10orf88 C8orf33 CALM1 CCDC113 CCT5 CDC37 CHD3 CSTF2 DISC1 ECSIT EEF1A1 EP300 EXOSC10 FAM173A FEZ1 FUBP1 HAP1 HIVEP1 HJURP HMOX2 HNRNPD KDM1A KIF22 KPNA2 LRIF1 MRPL44 NDEL1 NDUFB9 NEK2 NIPSNAP3A NOS3 PDE4DIP PFDN1 PIAS4 PLA2G15 PPOX PRRC2A RER1 SDHAF2 SMN1 SNAPIN SRRT STMN4 STX5 TAF1D TK1 TNNT1 TRAF3IP1 TUBGCP3 TXNDC9 UBQLN4
Entrez ID		22948	10989
HPRD ID		06468	02658
Ensembl ID		ENSG00000150753	ENSG00000132305
Uniprot IDs		B4DYD8 B7ZAR1 E7ENZ3 E9PCA1 P48643	B9A067 Q16891
PDB IDs
Enriched GO Terms of Interacting Partners?		Cellular Component Assembly Protein Complex Assembly Replicative Senescence Chromatin Organization Chromosome Organization 'de Novo' Posttranslational Protein Folding Heterotrimeric G-protein Complex Assembly Negative Regulation Of Production Of SiRNA Involved In RNA Interference Translocation Of Peptides Or Proteins Into Host Cell Cytoplasm 'de Novo' Protein Folding Protein Folding Cell Aging Negative Regulation Of Macromitophagy Negative Regulation Of RNA Interference Skeletal Muscle Fiber Adaptation Transcription, RNA-templated Oligodendrocyte Apoptotic Process Organelle Organization Negative Regulation Of Helicase Activity Telomere Formation Via Telomerase Age-dependent Telomere Shortening Telomere Maintenance Via Telomere Shortening Negative Regulation Of Protein Refolding Notch Signaling Pathway Positive Regulation Of Thymocyte Apoptotic Process Glomerular Mesangial Cell Development Positive Regulation Of Cell Aging Skeletal Muscle Thin Filament Assembly Mitochondrial DNA Repair Mesangial Cell Development Telomere Assembly Nuclear MRNA Surveillance Regulation Of Mitochondrion Degradation T Cell Proliferation Involved In Immune Response B Cell Lineage Commitment Renal Interstitial Fibroblast Development Glial Cell Apoptotic Process Circadian Rhythm Skeletal Myofibril Assembly Oxidative Stress-induced Premature Senescence RNA Surveillance	Organelle Organization Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Localization Nucleobase-containing Compound Metabolic Process Transcription, DNA-templated Microtubule-based Process RNA Metabolic Process RNA Biosynthetic Process Gene Expression Regulation Of Binding Regulation Of Metabolic Process Cellular Metabolic Process Posttranscriptional Regulation Of Gene Expression Establishment Of Localization In Cell Microtubule Polymerization Or Depolymerization Retrograde Axon Cargo Transport Regulation Of Gene Expression, Epigenetic Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cell Cycle Cellular Macromolecule Biosynthetic Process Chromosome Segregation Embryo Development Cellular Process Macromolecule Biosynthetic Process Axon Cargo Transport Regulation Of Protein Metabolic Process Microtubule-based Transport RNA Processing Brain Development Cytoskeleton-dependent Intracellular Transport Centrosome Separation Embryo Development Ending In Birth Or Egg Hatching Organelle Localization Nervous System Development Chromosome Organization Regulation Of Protein Binding Head Development Anatomical Structure Development Regulation Of Cellular Process Microtubule Cytoskeleton Organization Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Biosynthetic Process Microtubule-based Movement Regulation Of Oxidoreductase Activity Regulation Of RNA Metabolic Process Establishment Of Organelle Localization
Tagcloud ?		cd68 ddx5 enterovirus ft1dm fulminant helicase hnrnph1 hspa1l infiltrated inflamed insulitis iqgap1 lamin lcp1 lmnb1 microdissection moesin msn pdg phosphogluconate phosphorylase plastin protein1 psme1 samhd1 serpin serpinb6 tymp wars
Tagcloud (Difference) ?		cd68 ddx5 enterovirus ft1dm fulminant helicase hnrnph1 hspa1l infiltrated inflamed insulitis iqgap1 lamin lcp1 lmnb1 microdissection moesin msn pdg phosphogluconate phosphorylase plastin protein1 psme1 samhd1 serpin serpinb6 tymp wars
Tagcloud (Intersection) ?