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SUMO4 and HSPA1B
Number of citations of the paper that reports this interaction (PubMedID
16236267
)
0
Data Source:
HPRD
(in vivo)
SUMO4
HSPA1B
Description
small ubiquitin like modifier 4
heat shock protein family A (Hsp70) member 1B
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
SUMO Ligase Complex
Extracellular Region
Nucleus
Nucleoplasm
Cytoplasm
Mitochondrion
Endoplasmic Reticulum
Centrosome
Centriole
Cytosol
Cytoskeleton
Plasma Membrane
Focal Adhesion
Inclusion Body
Aggresome
Nuclear Speck
Vesicle
Protein-containing Complex
Perinuclear Region Of Cytoplasm
Extracellular Exosome
Blood Microparticle
Ficolin-1-rich Granule Lumen
Ribonucleoprotein Complex
Molecular Function
Protein Tag Activity
Ubiquitin-like Protein Ligase Binding
Nucleotide Binding
Virus Receptor Activity
G Protein-coupled Receptor Binding
RNA Binding
Signaling Receptor Binding
Protein Binding
ATP Binding
ATP Hydrolysis Activity
Enzyme Binding
Heat Shock Protein Binding
Ubiquitin Protein Ligase Binding
Histone Deacetylase Binding
Protein Folding Chaperone
Unfolded Protein Binding
C3HC4-type RING Finger Domain Binding
ATP-dependent Protein Disaggregase Activity
ATP-dependent Protein Folding Chaperone
Biological Process
Protein Sumoylation
Cellular Response To Oxidative Stress
Regulation Of Canonical NF-kappaB Signal Transduction
Positive Regulation Of DNA Binding
Negative Regulation Of DNA Binding
Negative Regulation Of DNA-templated Transcription
Regulation Of Protein Localization To Nucleus
MRNA Catabolic Process
Protein Folding
Negative Regulation Of Cell Population Proliferation
Positive Regulation Of Gene Expression
Negative Regulation Of Cell Growth
Regulation Of Protein Ubiquitination
Negative Regulation Of Protein Ubiquitination
Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Interleukin-8 Production
Cellular Response To Oxidative Stress
Cellular Response To Heat
Protein Refolding
Negative Regulation Of Apoptotic Process
Positive Regulation Of Erythrocyte Differentiation
ATP Metabolic Process
Symbiont Entry Into Host Cell
Protein Stabilization
Positive Regulation Of NF-kappaB Transcription Factor Activity
Cellular Heat Acclimation
Positive Regulation Of Nucleotide-binding Oligomerization Domain Containing 2 Signaling Pathway
Cellular Response To Steroid Hormone Stimulus
Positive Regulation Of Microtubule Nucleation
Negative Regulation Of Inclusion Body Assembly
Regulation Of Mitotic Spindle Assembly
Positive Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway
Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Pathways
Viral RNP Complexes in the Host Cell Nucleus
Regulation of HSF1-mediated heat shock response
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand
Attenuation phase
HSF1-dependent transactivation
AUF1 (hnRNP D0) binds and destabilizes mRNA
Neutrophil degranulation
PKR-mediated signaling
Mitochondrial unfolded protein response (UPRmt)
Regulation of HSF1-mediated heat shock response
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand
Attenuation phase
HSF1-dependent transactivation
Neutrophil degranulation
PKR-mediated signaling
Mitochondrial unfolded protein response (UPRmt)
Drugs
Diseases
GWAS
Dupuytren's disease (
28886342
)
Asthma (
31619474
)
Asthma (childhood onset) (
31619474
)
Asthma and major depressive disorder (
31619474
)
Autism spectrum disorder or schizophrenia (
28540026
)
Eosinophilic esophagitis (
29904099
)
Inflammatory bowel disease (
28067908
)
Systemic lupus erythematosus (
32771030
)
Ulcerative colitis (
28067908
)
Interacting Genes
75 interacting genes:
ACADM
ACO2
ACTG1
ALDOA
ARHGDIA
ATP5F1B
CALR
CAT
CCT2
CCT5
CCT6A
CCT7
CLIC1
DNAJA1
DNAJB11
EIF3I
ENO1
ENO2
FOS
G6PD
GAPDH
GMPS
GSTP1
HNRNPD
HNRNPF
HNRNPH1
HNRNPL
HSPA1B
HSPA5
HSPA8
HSPA9
HSPD1
IDH1
IDH3A
IMPDH2
JUN
LDHB
LMNA
LMNB1
MRPS22
NFKBIA
NR3C1
PA2G4
PAFAH1B3
PDIA3
PDIA6
PGK1
PHB1
PHGDH
PITHD1
PPA1
PRDX2
PRDX3
PRDX4
PRDX6
PRPS1
PSMC2
RACK1
RPSA
SF3B4
SPINT2
STAT1
STAT3
STIP1
STOML2
STRAP
TFAP2A
TOP2A
TPM3
TUBA1C
TXNL1
UBE2V1
VCP
VDAC1
ZPR1
25 interacting genes:
AIFM1
BAG1
BAG4
BNIP2
CEBPA
DNMBP
F2RL1
FAF1
FTCD
HSPBP1
MYBPC2
NEDD8
PGAM5
SGCG
SNCA
ST13
STUB1
SUMO4
TGM2
TOMM70
TRIM38
TTN
UBQLN2
YWHAB
YWHAZ
Entrez ID
387082
3304
HPRD ID
10584
06784
Ensembl ID
ENSG00000177688
ENSG00000204388
Uniprot IDs
Q6EEV6
A8K5I0
P0DMV8
P0DMV9
PDB IDs
1HJO
1S3X
1XQS
2E88
2E8A
2LMG
3A8Y
3ATU
3ATV
3AY9
3D2E
3D2F
3JXU
3LOF
3Q49
4IO8
4J8F
4PO2
4WV5
4WV7
5AQW
5AQX
5AQY
5AQZ
5AR0
5BN8
5BN9
5BPL
5BPM
5BPN
5GJJ
5MKR
5MKS
5XI9
5XIR
6FDT
6FHK
6G3R
6G3S
6JPV
6K39
6ZYI
7F4X
7F4Z
7F50
7FGM
7GY4
7GY5
7GY6
7GY7
7GY8
7GY9
7GYA
7GYB
7GYC
7GYD
7GYE
7GYF
7GYG
7GYH
7GYI
7GYJ
7GYK
7GYL
7GYM
7GYN
7GYO
7GYP
7GYQ
7GYR
7GYS
7GYT
7GYU
7GYV
7GYW
7GYX
7KW7
7Q4R
Enriched GO Terms of Interacting Partners
?
Extracellular Exosome
Protein Folding
ATP-dependent Protein Folding Chaperone
Unfolded Protein Binding
Protein Folding Chaperone
Cytoplasm
Purine Nucleotide Metabolic Process
Cytosol
Nucleotide Metabolic Process
Ubiquitin Protein Ligase Binding
Ribose Phosphate Metabolic Process
Regulation Of Apoptotic Process
Ficolin-1-rich Granule Lumen
Purine-containing Compound Metabolic Process
Regulation Of Programmed Cell Death
Identical Protein Binding
RNA Binding
Nucleoside Phosphate Metabolic Process
Nicotinamide Nucleotide Metabolic Process
Protein Refolding
ATP Metabolic Process
Secretory Granule Lumen
Purine Ribonucleotide Metabolic Process
Nucleobase-containing Small Molecule Metabolic Process
Peroxiredoxin Activity
Ribonucleotide Metabolic Process
Hydrogen Peroxide Catabolic Process
Negative Regulation Of Apoptotic Process
Nucleobase-containing Compound Metabolic Process
Cellular Response To Cytokine Stimulus
Negative Regulation Of Programmed Cell Death
Positive Regulation Of Telomerase RNA Localization To Cajal Body
Mitochondrion
Positive Regulation Of Telomere Maintenance Via Telomerase
Oxidoreductase Activity
Antioxidant Activity
Positive Regulation Of Protein Localization To Cajal Body
Chaperonin-containing T-complex
Positive Regulation Of Telomere Maintenance Via Telomere Lengthening
Ribonucleoprotein Complex
Small Molecule Metabolic Process
Generation Of Precursor Metabolites And Energy
Response To Peptide
Enzyme Binding
Regulation Of Telomerase RNA Localization To Cajal Body
Peroxidase Activity
Nucleus
Hydrogen Peroxide Metabolic Process
Response To Stress
Organophosphate Metabolic Process
Ubiquitin Protein Ligase Binding
Adenyl-nucleotide Exchange Factor Activity
Regulation Of Programmed Cell Death
Positive Regulation Of Programmed Cell Death
Protein Folding
Regulation Of Protein Catabolic Process
Positive Regulation Of Protein Catabolic Process
Regulation Of Apoptotic Process
Protein Domain Specific Binding
Positive Regulation Of Proteasomal Protein Catabolic Process
Regulation Of Protein Localization
Phosphoserine Residue Binding
Cytosol
Protein Sequestering Activity
Positive Regulation Of Proteolysis Involved In Protein Catabolic Process
Hsp70 Protein Binding
Positive Regulation Of Apoptotic Process
Regulation Of Signal Transduction
Positive Regulation Of Catabolic Process
Positive Regulation Of Small GTPase Mediated Signal Transduction
Regulation Of Protein Stability
Positive Regulation Of Proteolysis
Regulation Of Proteasomal Protein Catabolic Process
Regulation Of Proteolysis
Protein Tag Activity
Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Protein Kinase Regulator Activity
Regulation Of Intracellular Signal Transduction
Positive Regulation Of Smooth Muscle Cell Apoptotic Process
Response To Alkaloid
Positive Regulation Of ERAD Pathway
Response To Endoplasmic Reticulum Stress
ERAD Pathway
Regulation Of Cell Communication
Regulation Of Signaling
Dopamine Transport
Perinuclear Region Of Cytoplasm
Protein-folding Chaperone Binding
Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process
M Band
Regulation Of ERAD Pathway
Negative Regulation Of Apoptotic Process
Regulation Of Smooth Muscle Cell Apoptotic Process
Regulation Of Small GTPase Mediated Signal Transduction
Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Regulation Of Defense Response
Cellular Response To Stress
RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding
Regulation Of Establishment Of Protein Localization
Positive Regulation Of Neutrophil Mediated Killing Of Gram-negative Bacterium
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