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CCT5
Gene Name
chaperonin containing TCP1, subunit 5 (epsilon)
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Zona Pellucida Receptor Complex
Nucleolus
Cytoplasm
Centrosome
Cytosol
Chaperonin-containing T-complex
Microtubule
Cell Body
Extracellular Vesicular Exosome
Molecular Function
Protein Binding
ATP Binding
G-protein Beta-subunit Binding
Beta-tubulin Binding
Unfolded Protein Binding
Biological Process
Protein Folding
Binding Of Sperm To Zona Pellucida
Response To Virus
Cellular Protein Metabolic Process
'de Novo' Posttranslational Protein Folding
Toxin Transport
Pathways
Cargo trafficking to the periciliary membrane
Protein folding
Organelle biogenesis and maintenance
Prefoldin mediated transfer of substrate to CCT/TriC
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding
Association of TriC/CCT with target proteins during biosynthesis
Chaperonin-mediated protein folding
Assembly of the primary cilium
BBSome-mediated cargo-targeting to cilium
Formation of tubulin folding intermediates by CCT/TriC
Folding of actin by CCT/TriC
Drugs
Diseases
GWAS
Pain (
22956598
)
Protein-protein Interactions
15 interactors:
ACTA1
ACTA2
ACTB
HDAC3
IKBKAP
IMMT
PDCL
SSSCA1
SUMO4
TBC1D17
TCP1
TERT
THEG
TP53
XRN1
Entrez ID
22948
HPRD ID
06468
Ensembl ID
ENSG00000150753
Uniprot IDs
B4DYD8
B7ZAR1
E7ENZ3
E9PCA1
P48643
PDB IDs
Enriched GO Terms of Interacting Partners
?
Cellular Component Assembly
Protein Complex Assembly
Replicative Senescence
Chromatin Organization
Chromosome Organization
'de Novo' Posttranslational Protein Folding
Heterotrimeric G-protein Complex Assembly
Negative Regulation Of Production Of SiRNA Involved In RNA Interference
Translocation Of Peptides Or Proteins Into Host Cell Cytoplasm
'de Novo' Protein Folding
Protein Folding
Cell Aging
Negative Regulation Of Macromitophagy
Negative Regulation Of RNA Interference
Skeletal Muscle Fiber Adaptation
Transcription, RNA-templated
Oligodendrocyte Apoptotic Process
Organelle Organization
Negative Regulation Of Helicase Activity
Telomere Formation Via Telomerase
Age-dependent Telomere Shortening
Telomere Maintenance Via Telomere Shortening
Negative Regulation Of Protein Refolding
Notch Signaling Pathway
Positive Regulation Of Thymocyte Apoptotic Process
Glomerular Mesangial Cell Development
Positive Regulation Of Cell Aging
Skeletal Muscle Thin Filament Assembly
Mitochondrial DNA Repair
Mesangial Cell Development
Telomere Assembly
Nuclear MRNA Surveillance
Regulation Of Mitochondrion Degradation
T Cell Proliferation Involved In Immune Response
B Cell Lineage Commitment
Renal Interstitial Fibroblast Development
Glial Cell Apoptotic Process
Circadian Rhythm
Skeletal Myofibril Assembly
Oxidative Stress-induced Premature Senescence
RNA Surveillance
Tagcloud
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cd68
ddx5
enterovirus
ft1dm
fulminant
helicase
hnrnph1
hspa1l
infiltrated
inflamed
insulitis
iqgap1
lamin
lcp1
lmnb1
microdissection
moesin
msn
pdg
phosphogluconate
phosphorylase
plastin
protein1
psme1
samhd1
serpin
serpinb6
tymp
wars