SUMO4 and STIP1

Number of citations of the paper that reports this interaction (PubMedID 16236267)
0

Data Source:
HPRD (in vivo)

		SUMO4	STIP1
Description		small ubiquitin like modifier 4	stress induced phosphoprotein 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus SUMO Ligase Complex	Nucleus Cytoplasm Golgi Apparatus Cytosol Protein-containing Complex Protein Folding Chaperone Complex Dynein Axonemal Particle
	Molecular Function	Protein Tag Activity Ubiquitin-like Protein Ligase Binding	RNA Binding Protein Binding Hsp90 Protein Binding
	Biological Process	Protein Sumoylation Cellular Response To Oxidative Stress Regulation Of Canonical NF-kappaB Signal Transduction Positive Regulation Of DNA Binding Negative Regulation Of DNA Binding Negative Regulation Of DNA-templated Transcription Regulation Of Protein Localization To Nucleus	Cellular Response To Interleukin-7
Pathways			HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand RND1 GTPase cycle
Drugs			Copper
Diseases
GWAS		Dupuytren's disease ( 28886342)	A body shape index ( 34021172) Attention deficit hyperactivity disorder ( 21784300) Crohn's disease ( 28067908) Fruit consumption ( 32066663) Monocyte count ( 32888494) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		75 interacting genes: ACADM ACO2 ACTG1 ALDOA ARHGDIA ATP5F1B CALR CAT CCT2 CCT5 CCT6A CCT7 CLIC1 DNAJA1 DNAJB11 EIF3I ENO1 ENO2 FOS G6PD GAPDH GMPS GSTP1 HNRNPD HNRNPF HNRNPH1 HNRNPL HSPA1B HSPA5 HSPA8 HSPA9 HSPD1 IDH1 IDH3A IMPDH2 JUN LDHB LMNA LMNB1 MRPS22 NFKBIA NR3C1 PA2G4 PAFAH1B3 PDIA3 PDIA6 PGK1 PHB1 PHGDH PITHD1 PPA1 PRDX2 PRDX3 PRDX4 PRDX6 PRPS1 PSMC2 RACK1 RPSA SF3B4 SPINT2 STAT1 STAT3 STIP1 STOML2 STRAP TFAP2A TOP2A TPM3 TUBA1C TXNL1 UBE2V1 VCP VDAC1 ZPR1	35 interacting genes: ACD ACVR1 AIP APP CBX4 CDC37 CHD3 CLCN1 CLK1 EGFR ERBB2 FEZ2 FKBP5 HIPK2 HSP90AA1 HSPA14 HSPA1A HSPA4 HSPA8 LAMB2 LMO2 MAGED4 MAP3K8 OGT PIAS2 PIAS3 PIAS4 POT1 PRNP PTGES3 RASGRF1 SUMO2 SUMO4 UBE2I UBR5
Entrez ID		387082	10963
HPRD ID		10584	05454
Ensembl ID		ENSG00000177688	ENSG00000168439
Uniprot IDs		Q6EEV6	P31948 V9HW72
PDB IDs			1ELR 1ELW 2LNI 2NC9 3ESK 3FWV 7KW7
Enriched GO Terms of Interacting Partners?		Extracellular Exosome Protein Folding ATP-dependent Protein Folding Chaperone Unfolded Protein Binding Protein Folding Chaperone Cytoplasm Purine Nucleotide Metabolic Process Cytosol Nucleotide Metabolic Process Ubiquitin Protein Ligase Binding Ribose Phosphate Metabolic Process Regulation Of Apoptotic Process Ficolin-1-rich Granule Lumen Purine-containing Compound Metabolic Process Regulation Of Programmed Cell Death Identical Protein Binding RNA Binding Nucleoside Phosphate Metabolic Process Nicotinamide Nucleotide Metabolic Process Protein Refolding ATP Metabolic Process Secretory Granule Lumen Purine Ribonucleotide Metabolic Process Nucleobase-containing Small Molecule Metabolic Process Peroxiredoxin Activity Ribonucleotide Metabolic Process Hydrogen Peroxide Catabolic Process Negative Regulation Of Apoptotic Process Nucleobase-containing Compound Metabolic Process Cellular Response To Cytokine Stimulus Negative Regulation Of Programmed Cell Death Positive Regulation Of Telomerase RNA Localization To Cajal Body Mitochondrion Positive Regulation Of Telomere Maintenance Via Telomerase Oxidoreductase Activity Antioxidant Activity Positive Regulation Of Protein Localization To Cajal Body Chaperonin-containing T-complex Positive Regulation Of Telomere Maintenance Via Telomere Lengthening Ribonucleoprotein Complex Small Molecule Metabolic Process Generation Of Precursor Metabolites And Energy Response To Peptide Enzyme Binding Regulation Of Telomerase RNA Localization To Cajal Body Peroxidase Activity Nucleus Hydrogen Peroxide Metabolic Process Response To Stress Organophosphate Metabolic Process	SUMO Transferase Activity Protein Sumoylation Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Macromolecule Biosynthetic Process Protein Folding ATP-dependent Protein Folding Chaperone SUMO Ligase Activity Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Primary Metabolic Process Regulation Of Macromolecule Metabolic Process Negative Regulation Of DNA-templated Transcription PML Body Chaperone-mediated Protein Complex Assembly Unfolded Protein Binding Telomere Maintenance Via Telomerase Negative Regulation Of RNA Biosynthetic Process Regulation Of Metabolic Process RNA-templated DNA Biosynthetic Process Heat Shock Protein Binding Protein Refolding Negative Regulation Of RNA Metabolic Process Telomere Maintenance Via Telomere Lengthening Regulation Of DNA-templated Transcription Protein Folding Chaperone Complex Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of Protein Localization Regulation Of Signal Transduction Regulation Of Telomere Maintenance Via Telomerase Protein-folding Chaperone Binding ATP Binding Regulation Of RNA Metabolic Process Negative Regulation Of Metabolic Process Negative Regulation Of Signal Transduction Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Macromolecule Biosynthetic Process Ubiquitin Protein Ligase Binding Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Biosynthetic Process Regulation Of Telomere Maintenance Via Telomere Lengthening Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Intracellular Signal Transduction Negative Regulation Of Cell Communication Negative Regulation Of Signaling Protein Folding Chaperone Positive Regulation Of Signal Transduction Positive Regulation Of Metabolic Process Positive Regulation Of Intracellular Signal Transduction Regulation Of Transcription By RNA Polymerase II Regulation Of Signaling
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