SUMO4 and GNB2L1

Number of citations of the paper that reports this interaction (PMID 16236267)
15

Data Source:
HPRD (in vivo)

		SUMO4	GNB2L1
Gene Name		small ubiquitin-like modifier 4	guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Phagocytic Cup Nucleus Cytoplasm Mitochondrion Cytosol Cytoskeleton Small Ribosomal Subunit Dendrite Midbody Neuronal Cell Body Perikaryon Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome
	Molecular Function		Protein Kinase C Binding Receptor Binding Protein Binding Ion Channel Inhibitor Activity Cysteine-type Endopeptidase Activator Activity Involved In Apoptotic Process Enzyme Binding Protein Phosphatase Binding Protein Tyrosine Kinase Inhibitor Activity Receptor Tyrosine Kinase Binding Protein Complex Scaffold SH2 Domain Binding Protein Homodimerization Activity Poly(A) RNA Binding
	Biological Process	Protein Sumoylation	Osteoblast Differentiation Positive Regulation Of Protein Phosphorylation Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Cell Cycle Gastrulation Negative Regulation Of Gene Expression Viral Process Negative Regulation Of Translation Negative Regulation Of Wnt Signaling Pathway Negative Regulation Of Cell Growth Positive Regulation Of Cell Migration Positive Regulation Of CAMP Catabolic Process Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Protein Homooligomerization Regulation Of Protein Localization Positive Regulation Of Apoptotic Process Positive Regulation Of GTPase Activity Rhythmic Process Negative Regulation Of Phagocytosis Regulation Of Cell Division Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Regulation Of Cell Cycle Negative Regulation Of Protein Kinase B Signaling Positive Regulation Of Mitochondrial Depolarization Negative Regulation Of Protein Tyrosine Kinase Activity Regulation Of Establishment Of Protein Localization To Plasma Membrane Negative Regulation Of Hydrogen Peroxide-induced Neuron Death Regulation Of Establishment Of Cell Polarity Positive Regulation Of Gastrulation Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		75 interactors: ACADM ACO2 ACTG1 ALDOA ARHGDIA ATP5B CALR CAT CCT2 CCT5 CCT6A CCT7 CLIC1 DNAJA1 DNAJB11 EIF3I ENO1 ENO2 FOS G6PD GAPDH GMPS GNB2L1 GSTP1 HNRNPD HNRNPF HNRNPH1 HNRNPL HSPA1B HSPA5 HSPA8 HSPA9 HSPD1 IDH1 IDH3A IMPDH2 JUN LDHB LMNA LMNB1 MRPS22 NFKBIA NR3C1 PA2G4 PAFAH1B3 PDIA3 PDIA6 PGK1 PHB PHGDH PITHD1 PPA1 PRDX2 PRDX3 PRDX4 PRDX6 PRPS1 PSMC2 RPSA SF3B4 SPINT2 STAT1 STAT3 STIP1 STOML2 STRAP TFAP2A TOP2A TPM3 TUBA1C TXNL1 UBE2V1 VCP VDAC1 ZPR1	86 interactors: ADH1B ADRB2 AGTRAP AR AURKB BCL2L11 CCNA1 CDKN1A CHERP CSF2RB DDX19B DGCR14 DNM1 DYNLL1 EIF6 EPOR FBXW7 FYN GABRB3 GNB1 GOLM1 GRAP2 GRIN2B HABP4 HIF1A HNRNPH2 IFNAR1 IFNAR2 IFNR IGF1R IK IL2RB IL4R IL7R INSR ITGB1 ITGB2 ITGB5 ITGB7 JAK1 LARP4B LRP12 MAPK6 MKRN2 NFATC1 NR3C1 NSMAF PABPC1 PDE4D PLCG1 PLEC PRKAB2 PRKCA PRKCB PRKCD PRKCE PRKD1 PRPF31 PTN PTOV1 PTPRM RASA1 RASA3 RB1 RHOA SAT1 SLC27A6 SLC6A3 SRC SREK1 ST7 STAT1 STAT3 SUMO4 SYT1 TARDBP TBXA2R TCEB1 TCEB2 TNFRSF1A TP63 TP73 TSC22D4 TUBB TYK2 WDR83
Entrez ID		387082	10399
HPRD ID		10584	01503
Ensembl ID		ENSG00000177688	ENSG00000204628
Uniprot IDs		Q6EEV6	E9KL35 P63244
PDB IDs			3J3A 4AOW
Enriched GO Terms of Interacting Partners?		Protein Folding Regulation Of Cell Death Regulation Of Apoptotic Process Cellular Metabolic Process Response To Unfolded Protein Response To Stress Negative Regulation Of Cell Death 'de Novo' Protein Folding Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Toxin Transport Response To Organic Substance Nitrogen Compound Metabolic Process 'de Novo' Posttranslational Protein Folding Metabolic Process Cellular Response To Stress Heterocycle Metabolic Process Nucleobase-containing Compound Metabolic Process Response To Endoplasmic Reticulum Stress Generation Of Precursor Metabolites And Energy Regulation Of Cellular Protein Metabolic Process Response To Oxidative Stress Positive Regulation Of Cellular Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Process Response To Reactive Oxygen Species Small Molecule Metabolic Process Organic Acid Metabolic Process Hydrogen Peroxide Catabolic Process Regulation Of Protein Metabolic Process Carboxylic Acid Metabolic Process Protein Refolding Endoplasmic Reticulum Unfolded Protein Response Ribonucleoside Monophosphate Biosynthetic Process Carbohydrate Biosynthetic Process Cellular Response To Organic Substance MRNA Metabolic Process Cellular Response To Unfolded Protein Activation Of Signaling Protein Activity Involved In Unfolded Protein Response Positive Regulation Of Nuclease Activity Nucleoside Monophosphate Biosynthetic Process Gluconeogenesis Monocarboxylic Acid Metabolic Process ER-nucleus Signaling Pathway Catabolic Process Ribose Phosphate Biosynthetic Process Apoptotic Process Biosynthetic Process Cellular Response To Topologically Incorrect Protein	Signaling Cell Communication Cellular Response To Stimulus Signal Transduction Response To Stimulus Cell Surface Receptor Signaling Pathway Cellular Response To Organic Substance Intracellular Signal Transduction Response To Organic Substance Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Signaling Regulation Of Signal Transduction Response To External Stimulus Defense Response Viral Process Response To Stress Immune System Process Regulation Of Immune Response Regulation Of Body Fluid Levels Regulation Of Cell Proliferation Regulation Of Immune System Process Response To Abiotic Stimulus Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Protein Localization Positive Regulation Of Signal Transduction Regulation Of Cellular Localization Response To Cytokine Regulation Of Cell Death Regulation Of Cellular Process Cytokine-mediated Signaling Pathway Cellular Response To Cytokine Stimulus Platelet Activation Innate Immune Response Immune Response Regulation Of Phosphorylation Blood Coagulation Regulation Of Apoptotic Process Hemostasis Regulation Of Protein Phosphorylation Positive Regulation Of Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Cell Cycle Positive Regulation Of Transport Peptidyl-tyrosine Autophosphorylation Cellular Process Neurotrophin TRK Receptor Signaling Pathway Developmental Process Regulation Of Angiogenesis Positive Regulation Of Cellular Metabolic Process
Tagcloud ?		accumulating behcet ccr1 ccr3 ccr6 cd40 ctla4 elucidating fcrl3 han helpful hopefully il17 il23r immunoregulatory irf5 l2 mcp multisystemic mystery opn predisposition profound ptpn22 regimes stat4 tgfbr3 tgrbr3 ubac2	aiming aip alignment boar brms1 chordc1 clues cops6 csde1 csfv ddx5 domestic fever hemorrhagic hspa8 interactive metap2 nav1 ncbi ns5a phf5a polr1c ppp2r3c psmc3 suvec swine tmed10 tmem70 y2h
Tagcloud (Difference) ?		accumulating behcet ccr1 ccr3 ccr6 cd40 ctla4 elucidating fcrl3 han helpful hopefully il17 il23r immunoregulatory irf5 l2 mcp multisystemic mystery opn predisposition profound ptpn22 regimes stat4 tgfbr3 tgrbr3 ubac2	aiming aip alignment boar brms1 chordc1 clues cops6 csde1 csfv ddx5 domestic fever hemorrhagic hspa8 interactive metap2 nav1 ncbi ns5a phf5a polr1c ppp2r3c psmc3 suvec swine tmed10 tmem70 y2h
Tagcloud (Intersection) ?