SUMO4 and TXNL1

Number of citations of the paper that reports this interaction (PubMedID 16236267)
0

Data Source:
HPRD (in vivo)

		SUMO4	TXNL1
Description		small ubiquitin like modifier 4	thioredoxin like 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus SUMO Ligase Complex	Proteasome Complex Nucleus Cytoplasm Cytosol
	Molecular Function	Protein Tag Activity Ubiquitin-like Protein Ligase Binding	Protein-disulfide Reductase Activity Disulfide Oxidoreductase Activity
	Biological Process	Protein Sumoylation Cellular Response To Oxidative Stress Regulation Of Canonical NF-kappaB Signal Transduction Positive Regulation Of DNA Binding Negative Regulation Of DNA Binding Negative Regulation Of DNA-templated Transcription Regulation Of Protein Localization To Nucleus
Pathways			RHOBTB2 GTPase cycle RHOU GTPase cycle RHOBTB1 GTPase cycle RHOV GTPase cycle RND3 GTPase cycle RND2 GTPase cycle RND1 GTPase cycle
Drugs
Diseases
GWAS		Dupuytren's disease ( 28886342)	Cerebrospinal AB1-42 levels in normal cognition ( 29274321) Chronotype ( 30696823) Diverticular disease ( 30177863) General risk tolerance (MTAG) ( 30643258) Morning person ( 30696823) Number of sexual partners ( 30643258) Smoking status (ever vs never smokers) ( 30643258) Tourette's syndrome or obsessive-compulsive disorder ( 25158072)
Interacting Genes		75 interacting genes: ACADM ACO2 ACTG1 ALDOA ARHGDIA ATP5F1B CALR CAT CCT2 CCT5 CCT6A CCT7 CLIC1 DNAJA1 DNAJB11 EIF3I ENO1 ENO2 FOS G6PD GAPDH GMPS GSTP1 HNRNPD HNRNPF HNRNPH1 HNRNPL HSPA1B HSPA5 HSPA8 HSPA9 HSPD1 IDH1 IDH3A IMPDH2 JUN LDHB LMNA LMNB1 MRPS22 NFKBIA NR3C1 PA2G4 PAFAH1B3 PDIA3 PDIA6 PGK1 PHB1 PHGDH PITHD1 PPA1 PRDX2 PRDX3 PRDX4 PRDX6 PRPS1 PSMC2 RACK1 RPSA SF3B4 SPINT2 STAT1 STAT3 STIP1 STOML2 STRAP TFAP2A TOP2A TPM3 TUBA1C TXNL1 UBE2V1 VCP VDAC1 ZPR1	6 interacting genes: CDC42 CEBPA HSPB1 PSMC3 SH3BP4 SUMO4
Entrez ID		387082	9352
HPRD ID		10584	04335
Ensembl ID		ENSG00000177688	ENSG00000091164
Uniprot IDs		Q6EEV6	O43396 V9HW51
PDB IDs			1GH2 1WWY 9E8G 9E8H 9E8I 9E8J 9E8K 9E8L 9E8N 9E8O
Enriched GO Terms of Interacting Partners?		Extracellular Exosome Protein Folding ATP-dependent Protein Folding Chaperone Unfolded Protein Binding Protein Folding Chaperone Cytoplasm Purine Nucleotide Metabolic Process Cytosol Nucleotide Metabolic Process Ubiquitin Protein Ligase Binding Ribose Phosphate Metabolic Process Regulation Of Apoptotic Process Ficolin-1-rich Granule Lumen Purine-containing Compound Metabolic Process Regulation Of Programmed Cell Death Identical Protein Binding RNA Binding Nucleoside Phosphate Metabolic Process Nicotinamide Nucleotide Metabolic Process Protein Refolding ATP Metabolic Process Secretory Granule Lumen Purine Ribonucleotide Metabolic Process Nucleobase-containing Small Molecule Metabolic Process Peroxiredoxin Activity Ribonucleotide Metabolic Process Hydrogen Peroxide Catabolic Process Negative Regulation Of Apoptotic Process Nucleobase-containing Compound Metabolic Process Cellular Response To Cytokine Stimulus Negative Regulation Of Programmed Cell Death Positive Regulation Of Telomerase RNA Localization To Cajal Body Mitochondrion Positive Regulation Of Telomere Maintenance Via Telomerase Oxidoreductase Activity Antioxidant Activity Positive Regulation Of Protein Localization To Cajal Body Chaperonin-containing T-complex Positive Regulation Of Telomere Maintenance Via Telomere Lengthening Ribonucleoprotein Complex Small Molecule Metabolic Process Generation Of Precursor Metabolites And Energy Response To Peptide Enzyme Binding Regulation Of Telomerase RNA Localization To Cajal Body Peroxidase Activity Nucleus Hydrogen Peroxide Metabolic Process Response To Stress Organophosphate Metabolic Process	Host-mediated Perturbation Of Viral Process Macrophage Differentiation GBD Domain Binding Storage Vacuole Identical Protein Binding Modulation Of Process Of Another Organism Host-mediated Perturbation Of Symbiont Process Positive Regulation Of Catabolic Process RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Response To Vitamin B2 C/EBP Complex Positive Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Protein Kinase C Signaling Proteasome Complex Endothelin Receptor Signaling Pathway Involved In Heart Process Myeloid Leukocyte Differentiation CHOP-C/EBP Complex Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Protein Kinase C Inhibitor Activity Amino Acid Import Apolipoprotein A-I Receptor Binding Neuropilin Signaling Pathway White Fat Cell Proliferation SUMO Ligase Complex Transport Along Microtubule Positive Regulation Of Pinocytosis G Protein-coupled Receptor Signaling Pathway Involved In Heart Process Cardiac Neural Crest Cell Migration Involved In Outflow Tract Morphogenesis Regulation Of Intracellular Signal Transduction Microtubule-based Transport Cytoskeleton-dependent Intracellular Transport Positive Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis Positive Regulation Of Proteolysis Response To Phenylpropanoid RNA Polymerase II-specific DNA-binding Transcription Factor Binding Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Protein Catabolic Process Negative Regulation Of Hematopoietic Stem Cell Proliferation Rb-E2F Complex Regulation Of Protein Kinase C Signaling Proteasome-activating Activity Establishment Of Golgi Localization Spindle Fat Cell Proliferation Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis Myeloid Cell Differentiation Anterograde Axonal Protein Transport Leading Edge Membrane Thioesterase Binding Neuron Fate Determination
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