CCT5 and SSSCA1

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
HPRD (two hybrid)

		CCT5	SSSCA1
Gene Name		chaperonin containing TCP1, subunit 5 (epsilon)	Sjogren syndrome/scleroderma autoantigen 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Zona Pellucida Receptor Complex Nucleolus Cytoplasm Centrosome Cytosol Chaperonin-containing T-complex Microtubule Cell Body Extracellular Vesicular Exosome
	Molecular Function	Protein Binding ATP Binding G-protein Beta-subunit Binding Beta-tubulin Binding Unfolded Protein Binding	Protein Binding Identical Protein Binding
	Biological Process	Protein Folding Binding Of Sperm To Zona Pellucida Response To Virus Cellular Protein Metabolic Process 'de Novo' Posttranslational Protein Folding Toxin Transport	Mitotic Nuclear Division Cell Division
Pathways		Cargo trafficking to the periciliary membrane Protein folding Organelle biogenesis and maintenance Prefoldin mediated transfer of substrate to CCT/TriC Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding Association of TriC/CCT with target proteins during biosynthesis Chaperonin-mediated protein folding Assembly of the primary cilium BBSome-mediated cargo-targeting to cilium Formation of tubulin folding intermediates by CCT/TriC Folding of actin by CCT/TriC
Drugs
Diseases
GWAS		Pain ( 22956598)	Height ( 20881960)
Protein-Protein Interactions		15 interactors: ACTA1 ACTA2 ACTB HDAC3 IKBKAP IMMT PDCL SSSCA1 SUMO4 TBC1D17 TCP1 TERT THEG TP53 XRN1	20 interactors: ALS2CR11 C20orf195 CCDC33 CCNH CCT2 CCT3 CCT5 CCT7 FXR2 IL16 MYO15B NME6 NOC4L RNF115 SNAPC5 STAT3 SUMO1P1 TRAF3IP3 TRAPPC6A VTA1
Entrez ID		22948	10534
HPRD ID		06468	06921
Ensembl ID		ENSG00000150753	ENSG00000173465
Uniprot IDs		B4DYD8 B7ZAR1 E7ENZ3 E9PCA1 P48643	O60232
PDB IDs
Enriched GO Terms of Interacting Partners?		Cellular Component Assembly Protein Complex Assembly Replicative Senescence Chromatin Organization Chromosome Organization 'de Novo' Posttranslational Protein Folding Heterotrimeric G-protein Complex Assembly Negative Regulation Of Production Of SiRNA Involved In RNA Interference Translocation Of Peptides Or Proteins Into Host Cell Cytoplasm 'de Novo' Protein Folding Protein Folding Cell Aging Negative Regulation Of Macromitophagy Negative Regulation Of RNA Interference Skeletal Muscle Fiber Adaptation Transcription, RNA-templated Oligodendrocyte Apoptotic Process Organelle Organization Negative Regulation Of Helicase Activity Telomere Formation Via Telomerase Age-dependent Telomere Shortening Telomere Maintenance Via Telomere Shortening Negative Regulation Of Protein Refolding Notch Signaling Pathway Positive Regulation Of Thymocyte Apoptotic Process Glomerular Mesangial Cell Development Positive Regulation Of Cell Aging Skeletal Muscle Thin Filament Assembly Mitochondrial DNA Repair Mesangial Cell Development Telomere Assembly Nuclear MRNA Surveillance Regulation Of Mitochondrion Degradation T Cell Proliferation Involved In Immune Response B Cell Lineage Commitment Renal Interstitial Fibroblast Development Glial Cell Apoptotic Process Circadian Rhythm Skeletal Myofibril Assembly Oxidative Stress-induced Premature Senescence RNA Surveillance	Toxin Transport Binding Of Sperm To Zona Pellucida Sperm-egg Recognition 'de Novo' Posttranslational Protein Folding 'de Novo' Protein Folding Cell-cell Recognition Cell Recognition Single Fertilization Fertilization Protein Folding Sexual Reproduction Viral Process Reproduction Reproductive Process
Tagcloud ?		cd68 ddx5 enterovirus ft1dm fulminant helicase hnrnph1 hspa1l infiltrated inflamed insulitis iqgap1 lamin lcp1 lmnb1 microdissection moesin msn pdg phosphogluconate phosphorylase plastin protein1 psme1 samhd1 serpin serpinb6 tymp wars
Tagcloud (Difference) ?		cd68 ddx5 enterovirus ft1dm fulminant helicase hnrnph1 hspa1l infiltrated inflamed insulitis iqgap1 lamin lcp1 lmnb1 microdissection moesin msn pdg phosphogluconate phosphorylase plastin protein1 psme1 samhd1 serpin serpinb6 tymp wars
Tagcloud (Intersection) ?