CCT5 and PDCL

Number of citations of the paper that reports this interaction (PMID 15889144)
25

Data Source:
HPRD (in vivo)

		CCT5	PDCL
Gene Name		chaperonin containing TCP1, subunit 5 (epsilon)	phosducin-like
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Zona Pellucida Receptor Complex Nucleolus Cytoplasm Centrosome Cytosol Chaperonin-containing T-complex Microtubule Cell Body Extracellular Vesicular Exosome	Cytoplasm
	Molecular Function	Protein Binding ATP Binding G-protein Beta-subunit Binding Beta-tubulin Binding Unfolded Protein Binding	Receptor Signaling Protein Activity Protein Binding Protein Complex Binding
	Biological Process	Protein Folding Binding Of Sperm To Zona Pellucida Response To Virus Cellular Protein Metabolic Process 'de Novo' Posttranslational Protein Folding Toxin Transport	Protein Folding Signal Transduction Visual Perception Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Intracellular Signal Transduction Negative Regulation Of Protein Refolding Heterotrimeric G-protein Complex Assembly
Pathways		Cargo trafficking to the periciliary membrane Protein folding Organelle biogenesis and maintenance Prefoldin mediated transfer of substrate to CCT/TriC Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding Association of TriC/CCT with target proteins during biosynthesis Chaperonin-mediated protein folding Assembly of the primary cilium BBSome-mediated cargo-targeting to cilium Formation of tubulin folding intermediates by CCT/TriC Folding of actin by CCT/TriC
Drugs
Diseases
GWAS		Pain ( 22956598)	Obesity-related traits ( 23251661)
Protein-Protein Interactions		15 interactors: ACTA1 ACTA2 ACTB HDAC3 IKBKAP IMMT PDCL SSSCA1 SUMO4 TBC1D17 TCP1 TERT THEG TP53 XRN1	7 interactors: ADRBK1 CCT5 EIF3I GNB1 IKBKG PSMC5 TCP1
Entrez ID		22948	5082
HPRD ID		06468	05108
Ensembl ID		ENSG00000150753	ENSG00000136940
Uniprot IDs		B4DYD8 B7ZAR1 E7ENZ3 E9PCA1 P48643	Q13371
PDB IDs
Enriched GO Terms of Interacting Partners?		Cellular Component Assembly Protein Complex Assembly Replicative Senescence Chromatin Organization Chromosome Organization 'de Novo' Posttranslational Protein Folding Heterotrimeric G-protein Complex Assembly Negative Regulation Of Production Of SiRNA Involved In RNA Interference Translocation Of Peptides Or Proteins Into Host Cell Cytoplasm 'de Novo' Protein Folding Protein Folding Cell Aging Negative Regulation Of Macromitophagy Negative Regulation Of RNA Interference Skeletal Muscle Fiber Adaptation Transcription, RNA-templated Oligodendrocyte Apoptotic Process Organelle Organization Negative Regulation Of Helicase Activity Telomere Formation Via Telomerase Age-dependent Telomere Shortening Telomere Maintenance Via Telomere Shortening Negative Regulation Of Protein Refolding Notch Signaling Pathway Positive Regulation Of Thymocyte Apoptotic Process Glomerular Mesangial Cell Development Positive Regulation Of Cell Aging Skeletal Muscle Thin Filament Assembly Mitochondrial DNA Repair Mesangial Cell Development Telomere Assembly Nuclear MRNA Surveillance Regulation Of Mitochondrion Degradation T Cell Proliferation Involved In Immune Response B Cell Lineage Commitment Renal Interstitial Fibroblast Development Glial Cell Apoptotic Process Circadian Rhythm Skeletal Myofibril Assembly Oxidative Stress-induced Premature Senescence RNA Surveillance	G-protein Coupled Acetylcholine Receptor Signaling Pathway Toxin Transport Binding Of Sperm To Zona Pellucida Sperm-egg Recognition 'de Novo' Posttranslational Protein Folding 'de Novo' Protein Folding Cell-cell Recognition Negative Regulation Of The Force Of Heart Contraction By Chemical Signal Translocation Of Peptides Or Proteins Into Host Cell Cytoplasm Cell Recognition Single Fertilization Fertilization Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Positive Regulation Of Inclusion Body Assembly Cardiac Muscle Cell Apoptotic Process Apoptotic Process Negative Regulation Of Striated Muscle Contraction Muscle Cell Apoptotic Process Programmed Cell Death Response To Virus Regulation Of The Force Of Heart Contraction By Chemical Signal Cell Death Death Tachykinin Receptor Signaling Pathway Cellular Metabolic Process Negative Regulation Of Signal Transduction Protein Folding Cellular Protein Metabolic Process Positive Regulation Of Catecholamine Secretion Regulation Of Macrophage Apoptotic Process Negative Regulation Of Signaling Tubulin Complex Assembly Cellular Response To Prostaglandin E Stimulus Adenylate Cyclase-activating Dopamine Receptor Signaling Pathway Regulation Of Inclusion Body Assembly Regulation Of Signal Transduction Desensitization Of G-protein Coupled Receptor Protein Signaling Pathway
Tagcloud ?		cd68 ddx5 enterovirus ft1dm fulminant helicase hnrnph1 hspa1l infiltrated inflamed insulitis iqgap1 lamin lcp1 lmnb1 microdissection moesin msn pdg phosphogluconate phosphorylase plastin protein1 psme1 samhd1 serpin serpinb6 tymp wars	2h2o 4h2o adp adriamycin anticancer antigrowth bax chemotherapeutics cisplatin complexes elucidate far fluorescein iodide isothiocyanate jurkat molt mtt palladium predominately propidium regarded ribose sac satisfactory terpy thp treating warranted
Tagcloud (Difference) ?		cd68 ddx5 enterovirus ft1dm fulminant helicase hnrnph1 hspa1l infiltrated inflamed insulitis iqgap1 lamin lcp1 lmnb1 microdissection moesin msn pdg phosphogluconate phosphorylase plastin protein1 psme1 samhd1 serpin serpinb6 tymp wars	2h2o 4h2o adp adriamycin anticancer antigrowth bax chemotherapeutics cisplatin complexes elucidate far fluorescein iodide isothiocyanate jurkat molt mtt palladium predominately propidium regarded ribose sac satisfactory terpy thp treating warranted
Tagcloud (Intersection) ?