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SUMO4 and STRAP
Number of citations of the paper that reports this interaction (PubMedID
16236267
)
0
Data Source:
HPRD
(in vivo)
SUMO4
STRAP
Description
small ubiquitin like modifier 4
serine/threonine kinase receptor associated protein
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Nucleus
SUMO Ligase Complex
Nucleus
Cytoplasm
Cytosol
SMN Complex
SMN-Sm Protein Complex
Molecular Function
Protein Tag Activity
Ubiquitin-like Protein Ligase Binding
RNA Binding
MRNA Binding
Signaling Receptor Binding
Protein Binding
U2 SnRNP Binding
Biological Process
Protein Sumoylation
Cellular Response To Oxidative Stress
Regulation Of Canonical NF-kappaB Signal Transduction
Positive Regulation Of DNA Binding
Negative Regulation Of DNA Binding
Negative Regulation Of DNA-templated Transcription
Regulation Of Protein Localization To Nucleus
Negative Regulation Of Transcription By RNA Polymerase II
Alternative MRNA Splicing, Via Spliceosome
Spliceosomal SnRNP Assembly
MRNA Splicing, Via Spliceosome
MRNA Processing
RNA Splicing
Protein-RNA Complex Assembly
Neuron Differentiation
Maintenance Of Gastrointestinal Epithelium
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Pathways
Downregulation of TGF-beta receptor signaling
Downregulation of TGF-beta receptor signaling
Positive Regulation of CDH1 Gene Transcription
Drugs
Diseases
GWAS
Dupuytren's disease (
28886342
)
Interacting Genes
75 interacting genes:
ACADM
ACO2
ACTG1
ALDOA
ARHGDIA
ATP5F1B
CALR
CAT
CCT2
CCT5
CCT6A
CCT7
CLIC1
DNAJA1
DNAJB11
EIF3I
ENO1
ENO2
FOS
G6PD
GAPDH
GMPS
GSTP1
HNRNPD
HNRNPF
HNRNPH1
HNRNPL
HSPA1B
HSPA5
HSPA8
HSPA9
HSPD1
IDH1
IDH3A
IMPDH2
JUN
LDHB
LMNA
LMNB1
MRPS22
NFKBIA
NR3C1
PA2G4
PAFAH1B3
PDIA3
PDIA6
PGK1
PHB1
PHGDH
PITHD1
PPA1
PRDX2
PRDX3
PRDX4
PRDX6
PRPS1
PSMC2
RACK1
RPSA
SF3B4
SPINT2
STAT1
STAT3
STIP1
STOML2
STRAP
TFAP2A
TOP2A
TPM3
TUBA1C
TXNL1
UBE2V1
VCP
VDAC1
ZPR1
31 interacting genes:
ANXA1
CEBPA
CHEK2
FOXP1
GEMIN6
GEMIN7
MAP1B
MTRES1
NEIL3
NXF1
PBLD
PDPK1
PTEN
RN7SL1
RNU1-1
RNU2-1
SMAD2
SMAD3
SMAD6
SMAD7
SMN1
SMURF1
SNRPB
SNRPD2
SNRPD3
SNRPE
SUMO2
SUMO4
SZRD1
TGFBR1
TGFBR2
Entrez ID
387082
11171
HPRD ID
10584
05816
Ensembl ID
ENSG00000177688
ENSG00000023734
Uniprot IDs
Q6EEV6
Q9Y3F4
PDB IDs
Enriched GO Terms of Interacting Partners
?
Extracellular Exosome
Protein Folding
ATP-dependent Protein Folding Chaperone
Unfolded Protein Binding
Protein Folding Chaperone
Cytoplasm
Purine Nucleotide Metabolic Process
Cytosol
Nucleotide Metabolic Process
Ubiquitin Protein Ligase Binding
Ribose Phosphate Metabolic Process
Regulation Of Apoptotic Process
Ficolin-1-rich Granule Lumen
Purine-containing Compound Metabolic Process
Regulation Of Programmed Cell Death
Identical Protein Binding
RNA Binding
Nucleoside Phosphate Metabolic Process
Nicotinamide Nucleotide Metabolic Process
Protein Refolding
ATP Metabolic Process
Secretory Granule Lumen
Purine Ribonucleotide Metabolic Process
Nucleobase-containing Small Molecule Metabolic Process
Peroxiredoxin Activity
Ribonucleotide Metabolic Process
Hydrogen Peroxide Catabolic Process
Negative Regulation Of Apoptotic Process
Nucleobase-containing Compound Metabolic Process
Cellular Response To Cytokine Stimulus
Negative Regulation Of Programmed Cell Death
Positive Regulation Of Telomerase RNA Localization To Cajal Body
Mitochondrion
Positive Regulation Of Telomere Maintenance Via Telomerase
Oxidoreductase Activity
Antioxidant Activity
Positive Regulation Of Protein Localization To Cajal Body
Chaperonin-containing T-complex
Positive Regulation Of Telomere Maintenance Via Telomere Lengthening
Ribonucleoprotein Complex
Small Molecule Metabolic Process
Generation Of Precursor Metabolites And Energy
Response To Peptide
Enzyme Binding
Regulation Of Telomerase RNA Localization To Cajal Body
Peroxidase Activity
Nucleus
Hydrogen Peroxide Metabolic Process
Response To Stress
Organophosphate Metabolic Process
SMN-Sm Protein Complex
I-SMAD Binding
Spliceosomal SnRNP Assembly
Spliceosomal Complex Assembly
Heteromeric SMAD Protein Complex
7-methylguanosine Cap Hypermethylation
SMAD Protein Signal Transduction
U2 SnRNP
Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Protein-RNA Complex Assembly
Type I Transforming Growth Factor Beta Receptor Binding
U4 SnRNP
Response To Growth Factor
Methylosome
Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Small Nuclear Ribonucleoprotein Complex
Cellular Response To Growth Factor Stimulus
Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway
U1 SnRNP
Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway
U5 SnRNP
Regulation Of Epithelial To Mesenchymal Transition
RNA Splicing, Via Transesterification Reactions
Activin Receptor Binding
U2-type Prespliceosome Assembly
U12-type Spliceosomal Complex
PICln-Sm Protein Complex
Nucleoplasm
R-SMAD Binding
Regulation Of SMAD Protein Signal Transduction
Trophoblast Cell Migration
U7 SnRNP
U2-type Spliceosomal Complex
Embryonic Cranial Skeleton Morphogenesis
Activin Receptor Signaling Pathway
U2-type Catalytic Step 2 Spliceosome
U4/U6 X U5 Tri-snRNP Complex
Ureteric Bud Development
SMN Complex
Ubiquitin Protein Ligase Binding
Transforming Growth Factor Beta Receptor Signaling Pathway
Negative Regulation Of Ossification
Co-SMAD Binding
Gemini Of Cajal Bodies
Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
MRNA Splicing, Via Spliceosome
Mesonephric Tubule Development
Mesonephric Epithelium Development
SMAD Binding
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