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SUMO4 and PRPS1
Number of citations of the paper that reports this interaction (PMID
16236267
)
15
Data Source:
HPRD
(in vivo)
SUMO4
PRPS1
Gene Name
small ubiquitin-like modifier 4
phosphoribosyl pyrophosphate synthetase 1
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Cytosol
Molecular Function
Magnesium Ion Binding
Ribose Phosphate Diphosphokinase Activity
ATP Binding
Kinase Activity
Protein Homodimerization Activity
Biological Process
Protein Sumoylation
Carbohydrate Metabolic Process
5-phosphoribose 1-diphosphate Biosynthetic Process
Purine Nucleobase Metabolic Process
Purine Nucleotide Biosynthetic Process
Pyrimidine Nucleotide Biosynthetic Process
Nervous System Development
Ribonucleoside Monophosphate Biosynthetic Process
Pathogenesis
Phosphorylation
Urate Biosynthetic Process
Small Molecule Metabolic Process
Hypoxanthine Biosynthetic Process
Pathways
5-Phosphoribose 1-diphosphate biosynthesis
Myoclonic epilepsy of Lafora
Glycogen storage diseases
Metabolism of carbohydrates
Drugs
Diseases
GWAS
Protein-Protein Interactions
75 interactors:
ACADM
ACO2
ACTG1
ALDOA
ARHGDIA
ATP5B
CALR
CAT
CCT2
CCT5
CCT6A
CCT7
CLIC1
DNAJA1
DNAJB11
EIF3I
ENO1
ENO2
FOS
G6PD
GAPDH
GMPS
GNB2L1
GSTP1
HNRNPD
HNRNPF
HNRNPH1
HNRNPL
HSPA1B
HSPA5
HSPA8
HSPA9
HSPD1
IDH1
IDH3A
IMPDH2
JUN
LDHB
LMNA
LMNB1
MRPS22
NFKBIA
NR3C1
PA2G4
PAFAH1B3
PDIA3
PDIA6
PGK1
PHB
PHGDH
PITHD1
PPA1
PRDX2
PRDX3
PRDX4
PRDX6
PRPS1
PSMC2
RPSA
SF3B4
SPINT2
STAT1
STAT3
STIP1
STOML2
STRAP
TFAP2A
TOP2A
TPM3
TUBA1C
TXNL1
UBE2V1
VCP
VDAC1
ZPR1
5 interactors:
GORASP2
PRPS2
PRPSAP1
SPG21
SUMO4
Entrez ID
387082
5631
HPRD ID
10584
02413
Ensembl ID
ENSG00000177688
ENSG00000147224
Uniprot IDs
Q6EEV6
B7ZB02
P60891
PDB IDs
2H06
2H07
2H08
2HCR
3EFH
3S5J
4F8E
Enriched GO Terms of Interacting Partners
?
Protein Folding
Regulation Of Cell Death
Regulation Of Apoptotic Process
Cellular Metabolic Process
Response To Unfolded Protein
Response To Stress
Negative Regulation Of Cell Death
'de Novo' Protein Folding
Cellular Nitrogen Compound Metabolic Process
Negative Regulation Of Apoptotic Process
Negative Regulation Of Programmed Cell Death
Toxin Transport
Response To Organic Substance
Nitrogen Compound Metabolic Process
'de Novo' Posttranslational Protein Folding
Metabolic Process
Cellular Response To Stress
Heterocycle Metabolic Process
Nucleobase-containing Compound Metabolic Process
Response To Endoplasmic Reticulum Stress
Generation Of Precursor Metabolites And Energy
Regulation Of Cellular Protein Metabolic Process
Response To Oxidative Stress
Positive Regulation Of Cellular Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Process
Response To Reactive Oxygen Species
Small Molecule Metabolic Process
Organic Acid Metabolic Process
Hydrogen Peroxide Catabolic Process
Regulation Of Protein Metabolic Process
Carboxylic Acid Metabolic Process
Protein Refolding
Endoplasmic Reticulum Unfolded Protein Response
Ribonucleoside Monophosphate Biosynthetic Process
Carbohydrate Biosynthetic Process
Cellular Response To Organic Substance
MRNA Metabolic Process
Cellular Response To Unfolded Protein
Activation Of Signaling Protein Activity Involved In Unfolded Protein Response
Positive Regulation Of Nuclease Activity
Nucleoside Monophosphate Biosynthetic Process
Gluconeogenesis
Monocarboxylic Acid Metabolic Process
ER-nucleus Signaling Pathway
Catabolic Process
Ribose Phosphate Biosynthetic Process
Apoptotic Process
Biosynthetic Process
Cellular Response To Topologically Incorrect Protein
5-phosphoribose 1-diphosphate Biosynthetic Process
AMP Biosynthetic Process
Nucleotide Biosynthetic Process
Tagcloud
?
accumulating
behcet
ccr1
ccr3
ccr6
cd40
ctla4
elucidating
fcrl3
han
helpful
hopefully
il17
il23r
immunoregulatory
irf5
l2
mcp
multisystemic
mystery
opn
predisposition
profound
ptpn22
regimes
stat4
tgfbr3
tgrbr3
ubac2
Tagcloud (Difference)
?
accumulating
behcet
ccr1
ccr3
ccr6
cd40
ctla4
elucidating
fcrl3
han
helpful
hopefully
il17
il23r
immunoregulatory
irf5
l2
mcp
multisystemic
mystery
opn
predisposition
profound
ptpn22
regimes
stat4
tgfbr3
tgrbr3
ubac2
Tagcloud (Intersection)
?