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NCBP2 and EIF4G1
Number of citations of the paper that reports this interaction (PMID
15361857
)
29
Data Source:
HPRD
(in vivo)
NCBP2
EIF4G1
Gene Name
nuclear cap binding protein subunit 2, 20kDa
eukaryotic translation initiation factor 4 gamma, 1
Image
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
MRNA Cap Binding Complex
Nuclear Cap Binding Complex
Cytosol
Membrane
Eukaryotic Translation Initiation Factor 4F Complex
Molecular Function
Nucleotide Binding
RNA Cap Binding
RNA 7-methylguanosine Cap Binding
RNA Binding
Protein Binding
Poly(A) RNA Binding
Translation Initiation Factor Activity
Protein Binding
Translation Factor Activity, Nucleic Acid Binding
Poly(A) RNA Binding
Biological Process
Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay
Spliceosomal SnRNP Assembly
MRNA Splicing, Via Spliceosome
Transcription From RNA Polymerase II Promoter
Transcription Elongation From RNA Polymerase II Promoter
Termination Of RNA Polymerase II Transcription
7-methylguanosine MRNA Capping
MRNA Export From Nucleus
SnRNA Export From Nucleus
Regulation Of Translational Initiation
Histone MRNA Metabolic Process
RNA Splicing
Gene Expression
Viral Process
Gene Silencing By RNA
MRNA 3'-end Processing
NcRNA Metabolic Process
MRNA Cis Splicing, Via Spliceosome
Positive Regulation Of RNA Export From Nucleus
Positive Regulation Of Viral Transcription
Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay
Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay
Nuclear-transcribed MRNA Poly(A) Tail Shortening
Translation
Translational Initiation
Regulation Of Translational Initiation
Insulin Receptor Signaling Pathway
Gene Expression
Viral Process
Cytokine-mediated Signaling Pathway
Cellular Protein Metabolic Process
Pathways
mRNA Splicing
Formation of HIV-1 elongation complex containing HIV-1 Tat
RNA Polymerase II Transcription
Abortive elongation of HIV-1 transcript in the absence of Tat
HIV Infection
Formation of the Early Elongation Complex
Transport of the SLBP independent Mature mRNA
Tat-mediated elongation of the HIV-1 transcript
Cleavage of Growing Transcript in the Termination Region
Processing of Intronless Pre-mRNAs
RNA Polymerase II Pre-transcription Events
SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
HIV Life Cycle
Transport of Mature Transcript to Cytoplasm
HIV Transcription Elongation
SLBP independent Processing of Histone Pre-mRNAs
Nonsense-Mediated Decay (NMD)
Transport of Mature mRNA Derived from an Intronless Transcript
Processing of Capped Intron-Containing Pre-mRNA
Transport of the SLBP Dependant Mature mRNA
Transport of Mature mRNA derived from an Intron-Containing Transcript
mRNA Capping
Transport of Mature mRNAs Derived from Intronless Transcripts
mRNA Splicing - Minor Pathway
Metabolism of non-coding RNA
mRNA Splicing - Major Pathway
mRNA 3'-end processing
Late Phase of HIV Life Cycle
Formation of RNA Pol II elongation complex
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
snRNP Assembly
Formation of HIV elongation complex in the absence of HIV Tat
Processing of Capped Intronless Pre-mRNA
Formation of the HIV-1 Early Elongation Complex
RNA Polymerase II Transcription Termination
Transcription of the HIV genome
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
RNA Polymerase II Transcription Elongation
Translation initiation complex formation
IRS-mediated signalling
mTOR signalling
S6K1-mediated signalling
mTOR signalling
mTORC1-mediated signalling
AUF1 (hnRNP D0) destabilizes mRNA
IGF1R signaling cascade
Deadenylation-dependent mRNA decay
IRS-related events triggered by IGF1R
Eukaryotic Translation Initiation
S6K1 signalling
Cap-dependent Translation Initiation
PKB-mediated events
PI3K Cascade
Signaling by Insulin receptor
Nonsense-Mediated Decay (NMD)
Regulation of mRNA stability by proteins that bind AU-rich elements
Insulin receptor signalling cascade
Deadenylation of mRNA
Translation
ISG15 antiviral mechanism
Interferon Signaling
S6K1 signalling
Cytokine Signaling in Immune system
IRS-related events
L13a-mediated translational silencing of Ceruloplasmin expression
S6K1-mediated signalling
Antiviral mechanism by IFN-stimulated genes
mTORC1-mediated signalling
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Ribosomal scanning and start codon recognition
GTP hydrolysis and joining of the 60S ribosomal subunit
IRS-mediated signalling
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
PKB-mediated events
PI3K Cascade
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS
Protein-Protein Interactions
7 interactors:
DDX39B
EIF4G1
EIF5
HNRNPF
HNRNPH1
LZTS2
NCBP1
24 interactors:
ANXA5
CENPU
EIF3A
EIF3B
EIF3I
EIF4A1
EIF4A2
EIF4E
EIF5
GK
HNRNPD
HSPB1
HTRA2
MKNK1
MKNK2
NCBP1
NCBP2
PABPC1
PAK2
PDCD4
TRAF2
UBE3A
UPF2
ZFYVE9
Entrez ID
22916
1981
HPRD ID
05503
06774
Ensembl ID
ENSG00000114503
ENSG00000114867
Uniprot IDs
E9PAR5
P52298
B2RU06
B2RU10
B4DSI9
E7EUU4
E7EX73
E9PGM1
O95065
Q04637
Q96I65
PDB IDs
1H2T
1H2U
1H2V
1H6K
1N52
1N54
3FEX
3FEY
1LJ2
1UG3
2W97
4F02
Enriched GO Terms of Interacting Partners
?
MRNA Processing
MRNA Metabolic Process
RNA Processing
MRNA Splicing, Via Spliceosome
RNA Splicing, Via Transesterification Reactions
Regulation Of Translational Initiation
RNA Splicing
Nuclear Export
Nucleocytoplasmic Transport
Nuclear Transport
Regulation Of Translation
Gene Expression
MRNA Export From Nucleus
RNA Export From Nucleus
Posttranscriptional Regulation Of Gene Expression
MRNA 3'-end Processing
Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay
Regulation Of RNA Splicing
Viral Process
RNA 3'-end Processing
Regulation Of Gene Expression
MRNA Transport
Cellular Macromolecular Complex Assembly
RNA Transport
RNA Metabolic Process
Nuclear-transcribed MRNA Catabolic Process
Cytoplasmic Transport
RNA Localization
RNA Secondary Structure Unwinding
MRNA Catabolic Process
Ribonucleoprotein Complex Assembly
Negative Regulation Of DNA Damage Checkpoint
RNA Catabolic Process
Translational Initiation
Viral MRNA Export From Host Cell Nucleus
Spindle Midzone Assembly
Regulation Of DNA Damage Checkpoint
Microtubule Severing
Ribonucleoprotein Complex Biogenesis
Nucleobase-containing Compound Metabolic Process
MRNA Cis Splicing, Via Spliceosome
Positive Regulation Of MRNA 3'-end Processing
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Regulation Of MRNA 3'-end Processing
Regulation Of Metabolic Process
MRNA Cleavage
Cellular Nitrogen Compound Metabolic Process
Histone MRNA Metabolic Process
Aromatic Compound Catabolic Process
Regulation Of Translation
Regulation Of Translational Initiation
Posttranscriptional Regulation Of Gene Expression
Regulation Of Cellular Protein Metabolic Process
Regulation Of Protein Metabolic Process
RNA Catabolic Process
Translational Initiation
Nuclear-transcribed MRNA Catabolic Process
MRNA Catabolic Process
MRNA 3'-end Processing
RNA 3'-end Processing
Cellular Macromolecule Catabolic Process
Aromatic Compound Catabolic Process
Nuclear-transcribed MRNA Poly(A) Tail Shortening
MRNA Metabolic Process
Catabolic Process
Viral Process
Cellular Macromolecular Complex Assembly
Nuclear Export
MRNA Processing
Regulation Of Gene Expression
Translation
Nucleocytoplasmic Transport
Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay
Nuclear Transport
Regulation Of Metabolic Process
MRNA Export From Nucleus
Ribonucleoprotein Complex Assembly
Gene Expression
RNA Export From Nucleus
RNA Processing
Formation Of Translation Preinitiation Complex
Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay
MRNA Transport
RNA Transport
Cellular Protein Metabolic Process
RNA Localization
Ribonucleoprotein Complex Biogenesis
Regulation Of Cellular Process
Gene Silencing By RNA
Protein Metabolic Process
Cytoplasmic Transport
Cellular Metabolic Process
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
MRNA Cis Splicing, Via Spliceosome
MRNA Splicing, Via Spliceosome
RNA Splicing, Via Transesterification Reactions
Positive Regulation Of Extrinsic Apoptotic Signaling Pathway
Positive Regulation Of MRNA 3'-end Processing
Tagcloud
?
bioinformatics
box
burkitt
cacgtgt
carrying
cdk4
chip
compelling
consensus
consequently
copyright
imidazole
interesting
k562
leukaemia
myc
myelogenous
owing
p493
pi
polyamide
promoters
protected
pyrrole
qpcr
rationale
recognizes
reserved
rights
Tagcloud (Difference)
?
bioinformatics
box
burkitt
cacgtgt
carrying
cdk4
chip
compelling
consensus
consequently
copyright
imidazole
interesting
k562
leukaemia
myc
myelogenous
owing
p493
pi
polyamide
promoters
protected
pyrrole
qpcr
rationale
recognizes
reserved
rights
Tagcloud (Intersection)
?