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NCBP2 and EIF5
Number of citations of the paper that reports this interaction (PMID
11331597
)
38
Data Source:
HPRD
(in vitro)
NCBP2
EIF5
Gene Name
nuclear cap binding protein subunit 2, 20kDa
eukaryotic translation initiation factor 5
Image
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
MRNA Cap Binding Complex
Nuclear Cap Binding Complex
Cytoplasm
Cytosol
Plasma Membrane
Molecular Function
Nucleotide Binding
RNA Cap Binding
RNA 7-methylguanosine Cap Binding
RNA Binding
Protein Binding
Poly(A) RNA Binding
Translation Initiation Factor Activity
GTPase Activity
GTP Binding
Translation Factor Activity, Nucleic Acid Binding
Poly(A) RNA Binding
Biological Process
Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay
Spliceosomal SnRNP Assembly
MRNA Splicing, Via Spliceosome
Transcription From RNA Polymerase II Promoter
Transcription Elongation From RNA Polymerase II Promoter
Termination Of RNA Polymerase II Transcription
7-methylguanosine MRNA Capping
MRNA Export From Nucleus
SnRNA Export From Nucleus
Regulation Of Translational Initiation
Histone MRNA Metabolic Process
RNA Splicing
Gene Expression
Viral Process
Gene Silencing By RNA
MRNA 3'-end Processing
NcRNA Metabolic Process
MRNA Cis Splicing, Via Spliceosome
Positive Regulation Of RNA Export From Nucleus
Positive Regulation Of Viral Transcription
Translation
Translational Initiation
Regulation Of Translational Initiation
Gene Expression
Cellular Protein Metabolic Process
Pathways
mRNA Splicing
Formation of HIV-1 elongation complex containing HIV-1 Tat
RNA Polymerase II Transcription
Abortive elongation of HIV-1 transcript in the absence of Tat
HIV Infection
Formation of the Early Elongation Complex
Transport of the SLBP independent Mature mRNA
Tat-mediated elongation of the HIV-1 transcript
Cleavage of Growing Transcript in the Termination Region
Processing of Intronless Pre-mRNAs
RNA Polymerase II Pre-transcription Events
SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
HIV Life Cycle
Transport of Mature Transcript to Cytoplasm
HIV Transcription Elongation
SLBP independent Processing of Histone Pre-mRNAs
Nonsense-Mediated Decay (NMD)
Transport of Mature mRNA Derived from an Intronless Transcript
Processing of Capped Intron-Containing Pre-mRNA
Transport of the SLBP Dependant Mature mRNA
Transport of Mature mRNA derived from an Intron-Containing Transcript
mRNA Capping
Transport of Mature mRNAs Derived from Intronless Transcripts
mRNA Splicing - Minor Pathway
Metabolism of non-coding RNA
mRNA Splicing - Major Pathway
mRNA 3'-end processing
Late Phase of HIV Life Cycle
Formation of RNA Pol II elongation complex
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
snRNP Assembly
Formation of HIV elongation complex in the absence of HIV Tat
Processing of Capped Intronless Pre-mRNA
Formation of the HIV-1 Early Elongation Complex
RNA Polymerase II Transcription Termination
Transcription of the HIV genome
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
RNA Polymerase II Transcription Elongation
Ribosomal scanning and start codon recognition
GTP hydrolysis and joining of the 60S ribosomal subunit
Translation
Eukaryotic Translation Initiation
Cap-dependent Translation Initiation
Drugs
Diseases
GWAS
Red blood cell traits (
23222517
)
Protein-Protein Interactions
7 interactors:
DDX39B
EIF4G1
EIF5
HNRNPF
HNRNPH1
LZTS2
NCBP1
14 interactors:
APP
CSNK2A1
CSNK2B
DUSP12
EIF1AX
EIF1AY
EIF2S2
EIF3D
EIF3G
EIF4G1
EIF4G2
NCBP2
NRGN
PUM1
Entrez ID
22916
1983
HPRD ID
05503
03417
Ensembl ID
ENSG00000114503
ENSG00000100664
Uniprot IDs
E9PAR5
P52298
P55010
Q6IBU0
PDB IDs
1H2T
1H2U
1H2V
1H6K
1N52
1N54
3FEX
3FEY
2E9H
2G2K
2IU1
Enriched GO Terms of Interacting Partners
?
MRNA Processing
MRNA Metabolic Process
RNA Processing
MRNA Splicing, Via Spliceosome
RNA Splicing, Via Transesterification Reactions
Regulation Of Translational Initiation
RNA Splicing
Nuclear Export
Nucleocytoplasmic Transport
Nuclear Transport
Regulation Of Translation
Gene Expression
MRNA Export From Nucleus
RNA Export From Nucleus
Posttranscriptional Regulation Of Gene Expression
MRNA 3'-end Processing
Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay
Regulation Of RNA Splicing
Viral Process
RNA 3'-end Processing
Regulation Of Gene Expression
MRNA Transport
Cellular Macromolecular Complex Assembly
RNA Transport
RNA Metabolic Process
Nuclear-transcribed MRNA Catabolic Process
Cytoplasmic Transport
RNA Localization
RNA Secondary Structure Unwinding
MRNA Catabolic Process
Ribonucleoprotein Complex Assembly
Negative Regulation Of DNA Damage Checkpoint
RNA Catabolic Process
Translational Initiation
Viral MRNA Export From Host Cell Nucleus
Spindle Midzone Assembly
Regulation Of DNA Damage Checkpoint
Microtubule Severing
Ribonucleoprotein Complex Biogenesis
Nucleobase-containing Compound Metabolic Process
MRNA Cis Splicing, Via Spliceosome
Positive Regulation Of MRNA 3'-end Processing
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Regulation Of MRNA 3'-end Processing
Regulation Of Metabolic Process
MRNA Cleavage
Cellular Nitrogen Compound Metabolic Process
Histone MRNA Metabolic Process
Aromatic Compound Catabolic Process
Translational Initiation
Regulation Of Translation
Regulation Of Translational Initiation
Posttranscriptional Regulation Of Gene Expression
Translation
Regulation Of Cellular Protein Metabolic Process
Regulation Of Protein Metabolic Process
Cellular Protein Metabolic Process
Gene Expression
MRNA 3'-end Processing
Protein Metabolic Process
RNA 3'-end Processing
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Formation Of Translation Preinitiation Complex
Ribonucleoprotein Complex Assembly
Cellular Macromolecular Complex Assembly
Biosynthetic Process
Ribonucleoprotein Complex Biogenesis
Cellular Metabolic Process
SnRNA Export From Nucleus
Positive Regulation Of RNA Export From Nucleus
Synaptic Growth At Neuromuscular Junction
Formation Of Cytoplasmic Translation Initiation Complex
Axon Guidance
Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay
MRNA Processing
Collateral Sprouting In Absence Of Injury
Cytokine-mediated Signaling Pathway
Male Germ Cell Proliferation
Regulation Of Metabolic Process
Regulation Of Gene Expression
Collateral Sprouting
Axon Midline Choice Point Recognition
Axonogenesis
Cellular Component Assembly
Nuclear-transcribed MRNA Catabolic Process
MRNA Metabolic Process
Smooth Endoplasmic Reticulum Calcium Ion Homeostasis
MRNA Catabolic Process
Axon Choice Point Recognition
Axon Development
RNA Processing
Cellular Response To Cytokine Stimulus
Cell Morphogenesis Involved In Neuron Differentiation
Cytoplasmic Translational Initiation
Positive Regulation Of Glucokinase Activity
Positive Regulation Of Activin Receptor Signaling Pathway
Chemotaxis
Adiponectin-activated Signaling Pathway
Tagcloud
?
40s
429c
cdna
cdnas
cloning
deduced
eif3
encodes
eukaryotic
frame
homogeneity
identity
incorporated
initiator
laboratories
lysates
methionyl
mr35
multisubunit
p42
polyhistidine
reading
similarity
tagged
tif35p
transiently
trna
u20s
ydr
Tagcloud (Difference)
?
40s
429c
cdna
cdnas
cloning
deduced
eif3
encodes
eukaryotic
frame
homogeneity
identity
incorporated
initiator
laboratories
lysates
methionyl
mr35
multisubunit
p42
polyhistidine
reading
similarity
tagged
tif35p
transiently
trna
u20s
ydr
Tagcloud (Intersection)
?